Publications by authors named "Jia-Li Qi"
Impact of low-to moderate-intensity exercise training on the mRNA expression of purine receptors across various vessels in SHR.
Clin Hemorheol Microcirc
December 2024
Article Synopsis
- - The study aimed to investigate how exercise training affects blood pressure and mRNA expression levels of purine receptors in vascular tissues of spontaneously hypertensive rats (SHR) compared to control rats (WKY) during physical activity.
- - SHR and WKY rats were divided into sedentary and exercise groups, with the exercise group undergoing a 16-week treadmill regimen while their blood pressure and body weight were monitored along with purine receptor mRNA levels in different arteries.
- - Results showed that exercise led to a significant decrease in blood pressure for SHR rats, aligning their levels closer to WKY rats, while distinct changes in purine receptor mRNA expressions were observed across various blood vessels, indicating exercise's complex impact on vascular health.
Esophageal squamous cell carcinoma (ESCC), a major histologic subtype of esophageal cancer, is increasing in incidence, but the genetic underpinnings of this disease remain unexplored. The aim of this study is to identify the recurrent genetic changes, elucidate their roles and discover new biomarkers for improving clinical management of ESCC. Western blotting and immunohistochemistry were performed to detect the expression level of RHCG.
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