Publications by authors named "Jia-Li Huang"

Background: Our study examines the relationship between gastroesophageal reflux disease (GERD) and small intestinal bacterial overgrowth (SIBO), focusing on the potential impact of acid-suppressive drugs. We also explore changes in gut microbiota and metabolism in patients with both conditions.

Methods: This study included patients from the Department of Gastroenterology, Beijing Shijitan Hospital, between February 2021 and November 2023.

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Article Synopsis
  • Isobavachin (IBA) is a dihydroflavonoid with potential healh benefits, but its hepatotoxic effects need more research.
  • The study evaluated IBA’s impact on liver cell viability, revealing it has dose-dependent toxic effects and induces autophagy in specific liver cells.
  • Findings suggest that IBA inhibits key signaling proteins related to cell survival, but targeting certain pathways could help mitigate its liver toxicity, offering insights for clinical prevention and treatment.
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Objective: Belsky's parenting model provides insight into the relationship between parental psychological status and parenting behaviors. However, little is known about the unique associations of posttraumatic stress disorder (PTSD) symptoms with specific parenting behaviors. This study aimed to assess the associations of PTSD symptoms and three types of parenting behaviors (rejection, emotional warmth, and overprotection) with marital satisfaction, and to examine gender differences in these associations.

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"Preparedness for teaching" refers to the degree of confidence preservice teachers have, and reflects their ability. Developing preparedness for teaching is an important part of preservice teachers' professionalization. A substantial body of literature has documented the critical influence of the motivation to teach on preparedness; however, how this relation is impacted by mediating and moderating mechanisms remains unclear.

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This study aimed to examine the same-sex matching effect of posttraumatic stress disorder (PTSD) symptoms from parents to children and the mediating role of children' sense of security and catastrophization. Longitudinal data from 447 parent-child dyads were acquired using self-report scales. Parents (77.

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The study aimed to examine the indirect factors underlying the association between work-family conflict and posttraumatic stress symptoms (PTSS) in college teachers during the COVID-19 pandemic. Three potential indirect factors were examined: perceived stress, basic psychological needs, and rumination. A total of 274 college teachers were recruited.

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Background: Cerebral palsy (CP) is a neurodevelopmental disorder caused by a brain injury resulting in poor coordination and motor control deficits, which is one of the most common physical disabilities in children. CP brings a heavy burden on families and society and becomes a significant public health issue. In recent years, hydrotherapy, and transcranial direct current stimulation (tDCS) as a physical therapy for CP is developing rapidly.

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We present herein a visible-light-induced [3 + 2] cycloaddition of a hypervalent iodine(III) reagent with α-ketoacids for the construction of 5-CF-1,3,4-oxadiazoles that are of importance in medicinal chemistry. The reaction proceeds smoothly without a photocatalyst, metal, or additive under mild conditions. Different from the well-established trifluorodiazoethane (CFCHN), the diazotrifluoroethyl radical [CFC(·)N], a trifluoroethylcarbyne (CFCĊ:) equivalent and an unusual CF-containing building block, is involved in the present reaction system.

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Aim: To explore the function and mechanism of circular has_circ_PVT1 on laryngeal cancer (LC).

Methods: Microarray chip was performed to screen the differential expression of circRNA. Western blot and qRT-PCR was employed to detect the protein and mRNA level.

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Krüppel-like factor 8 (KLF8) is highly expressed in hepatocellular carcinoma (HCC) and contributes to tumor initiation and progression by promoting HCC cell proliferation and invasion. However, the role of KLF8 in liver cancer stem cells (LCSCs) is not known. In the current study, we investigated the role of KLF8 in LCSCs to determine if KLF8 is a novel marker of these cells.

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