SQSTM1/p62 is a prognostic molecular marker and potential therapeutic target for pancreatic neuroendocrine tumours.

Background: There have been few studies on the role of autophagy in pancreatic neuroendocrine tumours (PNETs). SQSTM1/p62 (also called Sequestosome 1) is a potential autophagy regulator, and its biological roles and clinical significance in PNETs remain poorly understood.

Purpose: The purpose of this study was to evaluate the clinical significance of SQSTM1/p62 in human PNET specimens and to evaluate its potential value as a therapeutic target by studying its biological function in PNET cell lines.

First report of causing leaf spot of in China.

Peanut ( L.), one of the most important oilseed crops in tropical and subtropical regions of the world (Kumar and Kirti 2011), is widely cultivated for its high protein and oil content in seeds. In August 2019, about 30% of plants were found infected by leaf spot in the peanut-growing regions of Shandong Province, China.

[Influence of Rainfall on the Growth of Dominant Algae Species in Xiangxi River].

To understand the influence of rainfall on the growth (in a culture cage) of dominant algae species in the Xiangxi River tributary of the Three Gorges Reservoir, culture experiments were carried out to measure the biomass of , , and before and after rainfall. The results showed that ① during the study period (October 4-18, 2017), there were significant differences in hydrodynamic conditions between the rainfall period and the non-rainfall period (ANOVA, <0.05).

conidia possess antiproliferative and inducing apoptosis properties in gynaecological carcinoma cells.

is an entomogenous fungus that has been used as a traditional Chinese medicinal materials to treat different diseases, including cancer. However, conidia for inhibitory activity against breast cancer cells growth are still not systematically studied. The present aim was to elucidate the phytochemical composition of conidia and to explore relevant anti-cancer potential in gynaecological carcinoma MCF-7 and Hela cells.

[Effects of spraying paclobutrazol at different stages on physiological characteristics, yield and quality of peanut].

To explore the optimum stage of spraying with paclobutrazol (PBZ) for different peanut cultivars under high yield condition, we investigated the effects of spraying PBZ at different stages on chlorophyll content, root activity, protective enzymes, nitrogen and carbon metabolism enzymes of leaves, pod yield and kernel quality of peanut, with Huayu 20 and Huayu 25 as materials. The results showed that spraying PBZ at different stages increased root activity, chlorophyll content, SOD, POD, CAT, SS, SPS, PEPC activities and decreased the MDA content, NR, GS, GDH and GOGAT activities for pod setting stage of two cultivars. These results suggested that the effects would be more obvious at earlier spray time.

[Vertical Stratification Characteristics of Dissolved Oxygen and Phytoplankton in Thousand-Island Lake and Their Influencing Factors].

According to the data collected from the five monitoring sites in front of the dam in Thousand-island Lake in September 2015, the vertical distribution characteristics of dissolved oxygen (DO), water temperature, pH, turbidity, conductivity and phytoplankton were analyzed. The influencing factors of special stratification of DO and vertical distribution of phytoplankton were also discussed. The results showed that:① The vertical distribution of DO presented "the surface is higher than the underlying" mode.

[Effects of exogenous Ca on growth and development, physiology and yield of peanut under salt stress].

Huayu 22, one of the peanut (Arachis hypogaea) cultivars, was used as material in this study. Peanuts, which grew under normal conditions and 100 mmol·L NaCl stress, were treated with 0, 6, 12 mmol·L Ca(NO) respectively to elucidate the effects of exogenous calcium on peanut salt tolerance. The effects of different Ca concentrations on the physiological indices and yield of peanut during the whole growth period under salt stress were investigated in potted plants, with the aim to provide theoretical basis for the growth and production of peanut in saline soil.

[Succession Pattern of Phytoplankton of Daning River in the Three Gorges Reservoir and Its Driving Factors].

To elucidate succession pattern of phytoplankton in the Daning River and its driving factors, multivariate statistical analysis was conducted. By using the monitoring data in different seasons of Daning river during April 2012 to January 2013, this paper analyzed the succession pattern of phytoplankton in the Daning River and its driving factors in typical tributaries of river-style reservoirs. According to the characteristics of water level, the operational period of the TGR was classified into following four stages:stage Ⅰ (pre-November-April), stage Ⅱ (May-July), stage Ⅲ (July-September) and stage Ⅳ (September-November).

[Effects of single-seed sowing on canopy microenvironment, photosynthetic characteristics and pod yield of peanut (Arachis hypogaca)].

The large-seed peanut cultivar of Huayu 22 was used to study the differences of canopy microenvironment, photosynthetic characteristics, and pod yield at three single-seed sowing densities, i.e., 225000 (S₁), 195000 (S₂) and 165000 (S₃) holes per hectare, in field experiments.

[Effects of calcium fertilizer application on peanut growth, physiological characteristics, yield and quality under drought stress].

An experiment was carried out to study the effects of different rates of calcium application on peanut growth, physiological characteristics, yield and quality under drought stress at pegging stage and pod setting stage in pool cultivation with rainproof, using variety 606 as experimental material. The results showed that applying Ca fertilizer under drought stress could promote peanut growth, increase the chlorophyll content, leaf photosynthetic rate and the root vitality, increase the recovery ability of peanut during rewatering after drought stress, alleviate the impact of drought stress on peanut. Applying Ca fertilizer under drought stress increased pod and kernel yields because of the increase of kernel rate and pod number per plant.

[Effects of paclobutrazol on the yield, quality, and related enzyme activities of different quality type peanut cultivars].

Selecting high-protein peanut cultivar KB008, high-fat cultivar Hual7, and high O/L cultivar Nongda818 as test materials, a field experiment was conducted in 2011 and 2012 to study the effects of foliar spraying paclobutrazol (PBZ) at late flowering stage on the kernel yield and quality and the activities of leaf carbon and nitrogen metabolism enzymes of the cultivars. Spraying PBZ increased the pod yield of the cultivars significantly via increasing the pod number per plant, decreasing the pod number per kilogram, and increasing the percentage of double kernel. Spraying PBZ also increased the kernel fat and soluble sugar contents but decreased the kernel protein content to varying degrees, and increased the O/L ratio of high-fat cultivar Hual7 significantly.

[Differences in seed kernel quality and related enzyme activities of different quality type peanut cultivars].

Taking high-protein peanut cultivar KB008, high-fat peanut cultivar Hual7 (H17), and high-oleic acid/linoleic acid (O/L) peanut cultivar Nongda818 as test materials, a field experiment was conducted in 2010 and 2011 to study the differences in the contents of protein, fat, and their components of the seed kernels, and the differences in the activities of the carbon and nitrogen metabolism enzymes related to the quality synthesis in the blades. As compared with that of H17 and Nongda818, the seed kernel of KB008 had significantly higher protein content but significantly lower soluble sugar content and O/L ratio, and the contents of the amino acid components, especially glutamic acid and lysine, in the seed kernel of KB008 were significantly higher. During the whole growth period, the activities of nitrate reductase (NR) , glutamine.

[Comparison of trophic status analysis of the Daning River within the Three Gorges Reservoir before and after experimental impoundment].

We evaluated 4-year data set to assess the trophic state and limiting factors of the Three Gorges Reservoir (TGR) during the experimental impounding period (September 2005 to September 2007) and the normal operating period (September 2008 to September 2010). The results indicated that there had been appeared new characteristics in spatial and temporal distribution of trophic state indices after impoundment. The trophic state indices (TSI(TP)) showed increased trend after the TGR impoundment during the study area, but TSI(TN) and TSI(SD) had no significant changes after the TGR impoundment.

[Effects of applying calcium on peanut physiological characteristics, its yield and kernel quality under cadmium stress].

Taking high-oil peanut cultivar Yuhua15 and high-protein peanut cultivar XB023 as test materials, a pot experiment was conducted in both 2009 and 2010 to study the effects of applying different concentration calcium (Ca) on the vegetative growth, leaf chlorophyll content, photosynthetic rate, and protective enzyme activities, as well as the yield and kernel quality of the cultivars under cadmium (Cd) stress. Applying Ca alleviated the inhibitory effects of Cd on the height growth of peanut main stem and the length growth of the branches, resulting in the increase of plant dry mass, and mitigated the Cd damage on peanut leaf, manifesting in the increase of leaf chlorophyll content, photosynthetic rate, superoxide dismutase (SOD), peroxidase (POD), and catlase (CAT) activities, and soluble protein content, and the decrease of leaf malondialdeyde (MDA) content. Under the application of Ca, both the pod yield and the kernel yield increased, mainly because of the increase of pod number per plant and of the kernel number per pod.

[Exploration of relationships between phytoplankton and related environmental factors in the Daning River during sensitive period of algal blooms].

To elucidate relationships between phytoplankton and related environmental factors, phytoplankton and environmental parameters of water quality in the Daning River were conducted using multivariate statistical analysis. Most of the investigated physico chemical parameters [water temperature, total nitrogen, nitrate-N (NO3(-) -N), pH and dissolved oxygen concentration (DO)] in Daning River are significantly different among those sampling sites (ANOVA, p < 0.05).

[Soil microbial biomass and respiration rate under effects of different planting patterns of peanut].

A field experiment with randomized design was conducted to study the effects of six planting patterns of peanut, i.e., spring sowing and plastic film mulching, spring sowing and open cultivation, summer sowing and plastic film mulching, summer sowing and open cultivation, intercropped in wheat field, and control of intercropped in wheat field, on soil microbial biomass C, soil active microbial biomass, and soil respiration rate.

[Systematic investigation into winter and spring algal blooms in Daning River of Three Gorges Reservoir].

According to the survey conducted from winter and spring algal blooms, the changes of water quality and characteristics of Daning River of Three Gorges Reservoir (TGR) were studied. The results suggested that during the period of winter algal blooms centered on Tangjia bay in Daning river, chlorophyll a (Chl-a) had a wide range (the rates of (Chl-a)max and (Chl-a)min is 260). The contents of total nitrogen (TN), total phosphorus (TP) and potassium permanganate index were at very high levels because of bioaccumulation from algal blooms, but the values of dissolved oxygen (DO) and pH were very low.

[Analysis of algal blooms in Da-Ning River of Three Gorges Reservoir].

According to the survey conducted from Apr. to Jun. 2007 and from Apr.