Statin Use and Delirium Risk: An Updated Systematic Review and Meta-Analysis.

Background: Findings on the association of statin use with delirium risk are inconsistent.

The Study Question: Is statin use associated with delirium risk?

Study Design: We searched PubMed, the Cochrane Library, and the EMBASE database, limiting the search to human patients and articles in English published until December 31, 2021. The effect size and 95% confidence interval (CI) were defined as the odds ratio (OR) and 95% CI, respectively, to indicate the difference in the incidence of delirium between statin use and nonuse groups.