Serine-modified silver nanoparticle porous spray membrane: A novel approach to wound infection prevention and inflammation reduction.

Traditional wound care preparations frequently face challenges such as complex care protocols, poor patient compliance, limited skin permeability, lack of aesthetics, and inconvenience, in addition to the risk of bacterial infection. We developed a spray film preparation containing nanocellulose and L-serine modified nanosilver, capable of rapidly forming a transparent film on the skin within minutes of application. The incorporation of nanocellulose imparted protective, moisturizing, and breathable properties to the film, allowing for easy removal after use.

SiO Induces Iron Overload and Ferroptosis in Cardiomyocytes in a Silicosis Mouse Model.

Objective: The aim of this study was to explore the role and mechanism of ferroptosis in SiO -induced cardiac injury using a mouse model.

Methods: Male C57BL/6 mice were intratracheally instilled with SiO to create a silicosis model. Ferrostatin-1 (Fer-1) and deferoxamine (DFO) were used to suppress ferroptosis.

Adhesive cryogel particles for bridging confined and irregular tissue defects.

Background: Reconstruction of damaged tissues requires both surface hemostasis and tissue bridging. Tissues with damage resulting from physical trauma or surgical treatments may have arbitrary surface topographies, making tissue bridging challenging.

Methods: This study proposes a tissue adhesive in the form of adhesive cryogel particles (ACPs) made from chitosan, acrylic acid, 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) and N-hydroxysuccinimide (NHS).

Pre-operative embolization, surgical resection, and follow-up evaluation of a giant intercostal schwannoma.

Intercostal schwannomas can present incidentally and lead to compressive thoracic symptoms. These slow-growing and benign tumors typically arise from intercostal nerves and are supplied by intercostal arteries, which may increase the risk of hemorrhagic complications with surgical resection. Due to the rarity of intercostal schwannomas, there exists no standardized management algorithms.

Biologic therapy for Crohn's disease over the last 3 decades.

Background: Despite the overload of publications on Crohn's disease (CD), no comprehensive analysis of biologic therapy for CD has been reported.

Aim: To determine knowledge gaps and identify areas of interest of biologic therapy for CD.

Methods: The top 100 highest-cited original articles were identified from January 1991 to December 2020 in the Clarivate Analytics Web of Science Core Collection database.

Artificial intelligence in gastroenterology and hepatology: Status and challenges.

Originally proposed by John McCarthy in 1955, artificial intelligence (AI) has achieved a breakthrough and revolutionized the processing methods of clinical medicine with the increasing workloads of medical records and digital images. Doctors are paying attention to AI technologies for various diseases in the fields of gastroenterology and hepatology. This review will illustrate AI technology procedures for medical image analysis, including data processing, model establishment, and model validation.

Laparoscopic surgery for early gallbladder carcinoma: A systematic review and meta-analysis.

Background: There is a controversy as to whether laparoscopic surgery leads to a poor prognosis compared to the open approach for early gallbladder carcinoma (GBC). We hypothesized that the laparoscopic approach is an alternative for early GBC.

Aim: To identify and evaluate the safety and feasibility of laparoscopic surgery in the treatment of early GBC.

Endovascular transsplenic recanalization with angioplasty and stenting of an occluded main portal vein in an adult liver transplant recipient.

Endovascular transshepatic access has limitations that can be exacerbated in the posttransplantation setting. Although several techniques are available for portal venous system catheterization, the transsplenic approach offers a direct pathway for accessing the portal venous system, as well as associated varices or shunts, while avoiding potential injury to the liver transplant. The purpose of this report is to present the diagnostic and interventional management of main portal vein occlusion in a 56-year-old female after liver transplantation.

Prognostic factors and predictors of postoperative adjuvant transcatheter arterial chemoembolization benefit in patients with resected hepatocellular carcinoma.

Background: Postoperative adjuvant transcatheter arterial chemoembolization (PA-TACE) has improved overall survival (OS) in patients with hepatocellular carcinoma (HCC). However, the prognostic and predictive factors remain unclear.

Aim: To assess the prognostic factors and the predictors of PA-TACE benefit for OS in patients with resected HCC.

Explore the relationship between fish community and environmental factors by machine learning techniques.

In the face of multiple habitat alterations originating from both natural and anthropogenic factors, the fast-changing environments pose significant challenges for maintaining ecosystem integrity. Machine learning is a powerful tool for modeling complex non-linear systems through exploratory data analysis. This study aims at exploring a machine learning-based approach to relate environmental factors with fish community for achieving sustainable riverine ecosystem management.