Publications by authors named "Jia-Fa Lu"
Article Synopsis
- * Researchers analyzed data from various studies, focusing on metrics such as overall survival, progression-free survival, response rates, and side effects, using a systematic review approach and statistical models.
- * Findings indicate that while COX-2 inhibitors did not improve overall survival or other key survival metrics, there was a better overall response rate in some cases, although they also led to increased severe side effects like blood toxicity and cardiovascular issues.
Aim: To investigate the association of PNPLA3 polymorphisms with concurrent chronic hepatitis B (CHB) and nonalcoholic fatty liver disease (NAFLD).
Methods: A cohort of Han patients with biopsy-proven CHB, with or without NAFLD (CHB group, n = 51; CHB + NAFLD group, n = 57), and normal controls (normal group, n = 47) were recruited from Northern (Tianjin), Central (Shanghai), and Southern (Zhangzhou) China. Their PNPLA3 polymorphisms were genotyped by gene sequencing.