Publications by authors named "Jia-Dai Liu"
Article Synopsis
- Beige fat activation shifts energy use to fatty acid oxidation after chronic cold exposure, involving a protein called ACSL1 located in mitochondria.
- Sortilin is an endosomal trafficking component that helps direct ACSL1 for degradation, affecting its levels in adipose tissues during beige fat activation.
- Lowering sortilin in fat cells raises mitochondrial ACSL1, boosts AMPK/PGC1α signaling, enhances beige fat activation, and may help combat obesity and insulin resistance linked to high-fat diets.
The Chinese mitten crab is an important economic species in the Chinese aquaculture industry due to its rich nutritional value and distinct flavor. The hepatopancreas is a popular edible part of the Chinese mitten crab, and therefore, hepatopancreatic health directly determines its quality. However, a large-scale outbreak of hepatopancreatic necrosis syndrome ("Shuibiezi" disease in Chinese), which is caused by abiotic agents correlated with cyanobacteria bloom outbreaks, adversely affects the Chinese mitten crab breeding industry.
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- - Eriocheir sinensis, a key aquaculture crab in China, faces health risks due to oxidative stress from poor water conditions, prompting a study on the effects of dietary reduced glutathione (GSH) at varying levels on their growth and immunity.
- - Results indicated that a GSH diet between 600 and 900 mg/kg improved weight gain, survival rates, and antioxidant enzyme activities, while 1200 mg/kg had negative effects.
- - The study found that GSH at optimal levels (600 or 900 mg/kg) significantly boosted the expression of beneficial antioxidant genes and reduced harmful substances, enhancing the overall health and resistance of E. sinensis to environmental stresses.
Eriocheir sinensis (E. sinensis) is an important aquaculture species in China. However, deteriorating water environments lead to oxidative stress in these crabs, which subsequently reduces their quality and yield.
View Article and Find Full Text PDFThis study investigated the effects of restricted feeding on the growth performance, oxidative stress and inflammation of Megalobrama amblycephala fed high-carbohydrate (HC) diets. Fish (46.94 ± 0.
View Article and Find Full Text PDFRegulation of mitochondrial biosynthesis and function by dietary carbohydrate levels and lipid sources in juvenile blunt snout bream Megalobrama amblycephala.
Comp Biochem Physiol A Mol Integr Physiol
January 2019
This study aimed to investigate the effects of dietary non-protein energy adjustments on the mitochondrial biosynthesis and function of juvenile Megalobrama amblycephala. Fish (average weight: 37.98 ± 0.
View Article and Find Full Text PDFUltraviolet-B (UVB) is one of the most cytotoxic and mutagenic stresses that contribute to skin damage and aging through increasing intracellular Ca(2+) and reactive oxygen species (ROS). Derinat (sodium deoxyribonucleate) has been utilized as an immunomodulator for the treatment of ROS-associated diseases in clinics. However, the molecular mechanism by which Derinat protects skin cells from UVB-induced damage is poorly understood.
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