Machine learning for the prediction of postoperative nosocomial pulmonary infection in patients with spinal cord injury.

Purpose: The purpose of this study was to establish the best prediction model for postoperative nosocomial pulmonary infection through machine learning (ML) and assist physicians to make accurate diagnosis and treatment decisions.

Methods: Patients with spinal cord injury (SCI) who admitted to a general hospital between July 2014 and April 2022 were included in this study. The data were segmented according to the ratio of seven to three, 70% were randomly selected to train the model, and the other 30% were used for testing.

Trend of unplanned reoperation rates after lumbar degenerative surgery from 2011 to 2019: a large patient population study.

Background: Unplanned reoperation is commonly performed due to postoperative complications. Previous studies have reported the incidence of unplanned reoperation following lumbar spinal surgery. But few study focused on the trend of reoperation rates, and the reasons of unplanned reoperation were not clear.

LRIG2 regulates cell proliferation, migration and apoptosis of osteosarcoma.

Background: Osteosarcoma (OS) is one of the malignant bone tumors with strong aggressiveness and poor prognosis. Leucine-rich repeats and immunoglobulin-like domains2 (LRIG2) is closely associated with the poor prognosis of a variety of tumors, but the role of LRIG2 in osteosarcoma and the underlying molecular mechanism remains unclear.

Objective: The aim of this study was to determine the function of LRIG2 in OS and the related molecular mechanism on cell proliferation, apoptosis and migration of OS.

Identification of mycobacterial bacterioferritin B for immune screening of tuberculosis and latent tuberculosis infection.

Objectives: It remains necessary and urgent to search for novel mycobacterial antigens to increase the sensitivity and specificity for tuberculosis (TB) diagnosis and latent TB infection (LTBI) screening. Antigens capable of inducing strong immune responses during Mycobacterium tuberculosis (M.tb) infection would be good candidates.

[Role of acetylcholine in gelsenicine-induced death in mice].

The aim of this study was to investigate the relationship between the acetylcholine concentration in the blood and gelsenicine-induced death in mice. Kunming mice were given intraperitoneal injections of normal saline, gelsenicine or different doses of acetylcholine chloride. Atropine was given to the mice which received gelsenicine or medium dose acetylcholine chloride injection.

Overexpression of chloride channel-3 is associated with the increased migration and invasion ability of ectopic endometrial cells from patients with endometriosis.

Study Question: Is chloride channel-3 (ClC-3) involved in regulating the biological behavior of endometrial stromal cells (ESCs)?

Summary Answer: ClC-3 promotes endometriotic cell migration and invasion.

What Is Known Already: ClC-3 plays a significant role in the migration and invasion of various kinds of cells.

Study Design, Size, Duration: An ITALIC! in vitro investigation of the effect of ClC-3 on the migration and invasion of ectopic ESCs from patients with endometriosis.

[Clinical application of alveolar ridge augment of posterior mandible using modified sandwich technique with immediate implantations].

Purpose: To evaluate the clinical values of alveolar ridge augment of atrophic posterior mandible using modified sandwich technique with immediate implantations,

Methods: Three patients with atrophic posterior mandible were enrolled in this study. A sandwich osteotomy was performed using a piezosurgery device, and 2 submerged implants were placed in approximal locations simultaneously to support and stabilize the osteotomy segments. Some xenografts were inserted into sandwich region and a GBR membrane was applied during operations.