Genome-Wide Identification and Expression Profiling of the Invertase Genes Involved in Sugar Metabolism and Accumulation in .

Invertase (INV, EC3.2.1.

Effects of different fermentation temperatures on microbiomes of cigar tobacco leaves.

Introduction: Microbiomes of cigar tobacco leaves play a pivotal role during the fermentation, and fermentation temperature is a key factor in shaping the structure and function of the microbial community. This study aimed to investigate the effects of different temperatures (30°C, 35°C, 40°C, 45°C, and 50°C) on the microbiomes of cigar tobacco leaves, providing insights into the complex interactions among temperature, microbes, and physicochemical metabolites.

Methods: Firstly, the physicochemical metabolites of cigar tobacco leaves under various fermentation temperatures were detected by gas chromatography-mass spectrometry.

A Comprehensive Analysis of FGF/FGFR Signaling Alteration in NSCLC: Implications in Prognosis and Microenvironment.

Fibroblast Growth Factor (FGF) ligands and their receptor have been identified as the potent target in non-small cell lung cancer (NSCLC). However, the clinicopathological and microenvironmental characteristics of FGF/FGFR in NSCLC remain poorly elucidated. Here, we summarize 4656 NSCLCs and analyze clinicopathological features in 478 FGF/FGFR altered cases.

Prophylactic cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for low-grade appendiceal mucinous tumors with early and limited disease after completely removed.

The necessity of prophylactic cytoreductive surgery (PCRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for low-grade appendiceal mucinous neoplasms (LAMN) after complete removal is still controversial. This study aims to determine the role of PCRS + HIPEC and identify optimal strategies for managing these patients. One hundred fifty-nine patients who sought medical advice at Aerospace Center Hospital were retrospectively analyzed from January 2011 to December 2021.

Effect of Combined Direct Current Electric Field and Pulsed Magnetic Field on the Transient Melt Pool in Laser Additive Manufacturing Process.

The application of a pulsed magnetic field (PMF) during a metallurgy solidification process has proven to be an effective method in refining the grain size and improving the mechanical performance of the material. However, fewer works were reported in the realm of laser additive manufacturing (LAM) and the mechanism of grain refinement consequent to the PMF is still unclear. In this work, numerical models were developed to study the thermal-fluid characteristics in the Ti-alloy melt pool generated during the laser scanning process under the effect of a combined direct current (DC) electric field and PMF.

The impact of gradient variable temperature fermentation on the quality of cigar tobacco leaves.

Introduction: In order to enhance the quality of cigar tobacco leaves (CTLs), a gradient variable temperature fermentation approach was employed.

Methods: The temperature gradient demonstrated a gradual increase from low temperature (35 ± 2°C) to moderate temperature (45 ± 2°C), and then to high temperature (55 ± 2°C). Each temperature gradient underwent a 10-day fermentation process, resulting in a total duration of 30 days.

Fermentation of cigar tobacco leaves with citrus flavonoids: changes in chemical, microbiological, and sensory properties.

Introduction: Fermentation plays a significant role in improving the quality of cigar tobacco leaves. Particularly, fermentation with characteristic additives has been identified as an effective approach to enhance the fermentation process. The objective of this study was to develop new additives and investigate their influence on cigar tobacco leaves.

Mechanochemically facilitated silver-catalyzed direct H/D exchange on heteroarenes.

Despite recent advances in H/D exchange, the effective deuteration of polyarenes remains challenging, due to their insolubility and hydrophobicity. This study presents a concept proofing of a mechanochemically facilitated direct H/D exchange. The silver-catalyzed deuteration of heteroarenes was promoted smoothly within 99 minutes of grinding, with heavy water as the deuterium source.

Equity analysis of older adult resource allocation in China.

Objective: To evaluate the current status and equity of older adult resource allocation in the 31 provinces (autonomous regions and municipalities) of mainland China, and to offer recommendations for the optimization of these allocations.

Methods: Four key indicators, namely, the number of older adult institutions, employees, professionals, and beds in mainland China in the year 2020, were used and analyzed using various methods and tools, including agglomeration analysis, the Gini coefficient, and the Lorenz Curve. These methods were applied to evaluate the equity of older adult resource allocation across the different provinces (autonomous regions and municipalities) and regions of China, using two dimensions, namely, the geographical area and the older adult population.

The bimolecular reactive transport in heterogeneous porous media: Sub-diffusion in interpretation of laboratory experiment.

This present work consists of investigating the effects of particle size heterogeneity and flow rates on transport-reaction kinetics of CuSO and NaEDTA in porous media, via the combination of a bimolecular reaction experiment and model simulations. In the early stages of transport, a peak is observed in the concentration breakthrough curve of the reactant CuSO, related to the delayed mixing and reaction of the reactants. The numerical results show that an increase in flow rate promotes the mixing processes between the reactants, resulting in a larger peak concentration and a slighter tail of breakthrough curves, while an increase in medium heterogeneity leads to a more significant heavy tail.

H/D Exchange of Aromatic Sulfones via Base Promotion and Silver Catalysis.

Aromatic sulfones are the prevailing scaffolds in pharmaceutical and material sciences. However, compared to their widespread application, the selective deuterium labeling of these structures is restricted due to their electron-deficient properties. This study presents two comprehensive strategies for the deuteration of aromatic sulfones.

Engineering the surface roughness of the gold nanoparticles for the modulation of LSPR and SERS.

In this work, we reported that by using a strong thiol ligand as the morphology-directing reagent, a series of Au nanoparticles with plate-like surface sub-structures could be successfully obtained via a one-pot seedless synthesis. The size and the density of the plates on the surface of Au can be readily tuned with the amount of the thiol ligand, resembling different roughness of the surface. Arising from the different surface roughness, the localized surface plasmon resonance (LSPR) of these shape and morphological alike Au nanoparticles can be continuously tuned within the visible-NIR region.

Characteristics of the time processing of adults' strongest sustained attentional bias toward neutral infant faces.

Previous studies have shown that adults exhibit the strongest attentional bias toward neutral infant faces when viewing faces with different expressions at different attentional processing stages due to different stimulus presentation times. However, it is not clear how the characteristics of the temporal processing associated with the strongest effect change over time. Thus, we combined a free-viewing task with eye-tracking technology to measure adults' attentional bias toward infant and adult faces with happy, neutral, and sad expressions of the same face.

Information Needs and Its Association With Depressive Symptoms in People With Type 2 Diabetes.

Purpose: The purpose of this study was to describe the information needs and examine its association with depressive symptoms in people with type 2 diabetes (T2D).

Methods: A descriptive, correlational design was used. People with T2D (N = 358) were recruited from 12 communities in Shanghai, China.

Sensory attributes, chemical and microbiological properties of cigars aged with different media.

Aging is an important process to improve the quality of cigar, but the effect of aging with media on cigar has not been reported.Therefore, this study aimed to prepare different aging media and clarify the influence of media on cigar quality. Effective media were first screened by sensory evaluation, then the effects of aging media on the chemical composition and microbial community of cigar were investigated.

Ultrasonic-pretreated hydrothermal synthesis of less dense zeolite CHA from the transformation of zeolite T.

Because of containing the same double 6-ring (D6R) building unit, the pure zeolite CHA with lower framework density (FD = 15.1 T/1000 Å) has been transformed from zeolite T with higher framework density (FD = 16.1 T/1000 Å) through ultrasonic-pretreated hydrothermal synthesis in MOH (KOH and NaOH) solution without adding organic template or seed crystals.

A critical assessment of the strains isolated from cigar tobacco leaves.

genus plays a crucial role in cigar fermentation, and strains from different sources might have differences in metabolic characteristics. Therefore, this study conducted directional isolation of strains from cigar tobacco leaves and compared their fermentabilities to screen suitable strains for cigar fermentation, thereby improving the cigar quality. First, the strains from cigars tobacco leaves in different production areas were directionally isolated by pure culture.

Effect of processing on aroma intensity and odor characteristic of Shuixian () tea.

Processing is extremely important for the formation of aroma characteristic of tea leaves. In this study, the effects of processing on the content of volatile compounds, aroma intensity and odor characteristic of Shuixian tea were analyzed. The results showed that the content of volatile compounds in Shuixian tea increased significantly after processing, among which terpenoids and esters were the highest.

Development of autochthonous starter for cigar fermentation dissecting the microbiome.

Introduction: The main goal of tobacco fermentation technology is to minimize the alkaloid content while improving flavor substance content.

Methods: This study revealed the microbial community structure and their metabolic functions during cigar leaf fermentation by high-throughput sequencing and correlation analysis, and evaluated the fermentation performance of functional microbes based on in vitro isolation and bioaugmentation fermentation.

Results: The relative abundance of and increased first but then decreased during the fermentation, and would occupy the dominant position of bacterial and fungal communities, respectively, on the 21st day.

MiR-5195-3p functions as a tumor suppressor by targeting RHBDD1 in ovarian cancer.

Background: Recent studies have reported the tumor suppressive role of miR-5195-3p in the progression of several cancers, but the potential roles of miR-5195-3p in ovarian cancer (OC) remain largely unknown.

Methods: We first analyzed the expression levels of miR-5195-3p in 83 pairs of human OC tissues and adjacent specimens by reverse transcription-quantitative PCR. The correlation of miR-5195-3p/rhomboid domain containing 1 (RHBDD1) and clinicopathological parameters was analyzed by chi-square test.

The hybridization origin of the Chinese endemic herb genus Notopterygium (Apiaceae): Evidence from population genomics and ecological niche analysis.

Hybridization is recognized as a major force in species evolution and biodiversity formation, generally leading to the origin and differentiation of new species. Multiple hybridization events cannot easily be reconstructed, yet they offer the potential to study a number of evolutionary processes. Here, we used nuclear expressed sequence tag-simple sequence repeat and large-scale single nucleotide polymorphism variation data, combined with niche analysis, to investigate the putative independent hybridization events in Notopterygium, a group of perennial herb plants endemic to China.