The novel HLA-B*40:536N allele, identified by Sanger dideoxy nucleotide sequencing in a Chinese individual.

HLA-B*40:536N differs from HLA-B*40:03:01:01 by one nucleotide in exon 3.

Suspended particulate matter-associated environmental corticosteroids in the Pearl River, China: Occurrence, distribution, and partitioning.

Suspended particulate matter (SPM) plays an important role in the geochemical behavior and fate of organic micropollutants in aquatic environments. However, the presence of trace emerging endocrine disruptors such as environmental corticosteroids (ECs) in SPM is less well understood. This study focused on the occurrence, distribution, and partitioning of SPM-associated ECs in the Pearl River system, China.

Microbial spectrum and drug resistance of pathogens cultured from gallbladder bile specimens of patients with cholelithiasis: A single-center retrospective study.

Background: Bacterial infection is an important cause of cholelithiasis or gallstones and interferes with its treatment. There is no consensus on bile microbial culture profiles in previous studies, and identified microbial spectrum and drug resistance is helpful for targeted preventive and therapeutic drugs in the perioperative period.

Aim: To analyze the bile microbial spectrum of patients with cholelithiasis and the drug susceptibility patterns in order to establish an empirical antibiotic treatment for cholelithiasis-associated infection.

Impact of Transversus Abdominis Plane Block With Bupivacaine or Ropivacaine Versus Intrathecal Morphine on Opioid-related Side Effects After Cesarean Delivery: A Meta-analysis of Randomized Controlled Trials.

Objectives: Intrathecal morphine (ITM) is frequently associated with side effects such as postoperative nausea and vomiting (PONV) and pruritus. The aim of this meta-analysis was to compare the impact of transversus abdominis plane (TAP) block versus ITM on side effects following cesarean delivery.

Materials And Methods: PubMed, Embase, Web of Science, and CENTRAL were searched for randomized controlled trials that compared TAP with ITM for cesarean delivery.

Rhizoma Bletillae polysaccharide elicits hemostatic effects in platelet-rich plasma by activating adenosine diphosphate receptor signaling pathway.

Rhizoma Bletillae, the tubes of Bletilla striata, has been traditionally used in China as a hemostatic agent. In preliminary studies, the major active fraction responsible for its hemostatic effect have been confirmed to be Rhizoma Bletillae polysaccharide (RBp), but the hemostatic mechanism of action of RBp is still unknown.The main aim of this study was to clarify its mechanism of hemostatic effect.

Low T3 syndrome is a prognostic marker of poor outcomes in secondary hemophagocytic lymphohistiocytosis.

This study aimed to examine the association between low T3 syndrome and overall survival (OS) in patients with secondary hemophagocytic lymphohistiocytosis (sHLH). The study consisted of 111 consecutive patients hospitalized due to newly diagnosed sHLH with detailed thyroid hormone profiles on admission. Low T3 syndrome was found in 75.

Hydrogen bonding and fluorous weak interactions in the non-isomorphous {4,4'-bis[(2,2,3,3-tetrafluoropropoxy)methyl]-2,2'-bipyridine-κN,N'}dibromidopalladium and -platinum complexes.

The polyfluorinated title compounds, [MBr(CHFNO)] or [4,4'-(HCFCFCHOCH)-2,2'-bpy]MBr, (1) (M = Pd and bpy is bipyridine) and (2) (M = Pt), have -CHOCHCFCFH side chains with methylene H-atom donors at the α and β sites, and methine H-atom donors at the terminal sites, in addition to aromatic H-atom donors. In contrast to the original expectation of isomorphous structures, (1) crystallizes in the space group C2/c and (2) in P2/n, with similar unit-cell volumes and Z = 4. The asymmetric unit of (1) is one half of the molecule, which resides on a crystallographic twofold axis.

Signal Amplified Gold Nanoparticles for Cancer Diagnosis on Paper-Based Analytical Devices.

In this work, we report a highly sensitive colorimetric sensing strategy for cancer biomarker diagnosis using gold nanoparticles (AuNPs) labeled with biotinylated poly(adenine) ssDNA sequences and streptavidin-horseradish peroxidase for enzymatic signal enhancement. By adopting this DNA-AuNP nanoconjugate sensing strategy, we were able to eliminate the complicated and costly thiol-binding process typically used to modify AuNP surfaces with ssDNA. In addition, different antibodies can be introduced to the AuNP surfaced via electrostatic interactions to provide highly specific recognition sites for biomolecular sensing.

Complete mitochondrial genome of (Teleostei: Amblycipitidae).

The complete mitochondrial genome of was sequenced by the long and accurate polymerase chain reaction and primer walking sequence method, and each partition was characterized. This genome, with 16,515 bp in length, includes 13 protein-coding genes, 22 tRNA genes, 2rRNA genes, and 2 non-coding regions. Genes encoding on the genome are similar among all vertebrates.

Size-tunable copper nanocluster aggregates and their application in hydrogen sulfide sensing on paper-based devices.

Polystyrene sulfonate (PSS), a strong polyelectrolyte, was used to prepare red photoluminescent PSS-penicillamine (PA) copper (Cu) nanoclusters (NC) aggregates, which displayed high selectivity and sensitivity to the detection of hydrogen sulfide (H2S). The size of the PSS-PA-Cu NC aggregates could be readily controlled from 5.5 μm to 173 nm using different concentrations of PSS, which enabled better dispersity and higher sensitivity towards H2S.

Platelet count and erythrocyte sedimentation rate are good predictors of Kawasaki disease: ROC analysis.

Background And Aims: Kawasaki disease (KD) is the leading cause of acquired pediatric cardiac disease and requires a timely diagnosis. Available effective therapy is ideally administered within 10 days of illness diagnosis. Recent reports of several laboratory tests in KD have been published.

[Changes of dendritic cells and its subsets in peripheral blood of patients with Mycobacterium tuberculosis].

Aim: To analyze the changes of dendritic cells and its subsets in peripheral blood of patients with mycobacterium tuberculosis, and to explore its immune mechanism.

Methods: 32 patients with mycobacterium tuberculosis and 11 healthy controls were selected, who were diagnosed in our hospital from Nov. 2008 to Aug.