Publications by authors named "Jia You Luo"

Article Synopsis
  • The objective of the study was to summarize existing research on genetic variants linked to nonalcoholic fatty liver disease (NAFLD).
  • A systematic search of literature from various databases yielded 399 studies, leading to the identification of 465 genetic variants across many genes.
  • The meta-analysis found 11 significant genetic variants associated with NAFLD, providing moderate to strong evidence for six variants in five genes that could enhance understanding of NAFLD risk.
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Objectives: To investigate the prevalence rate of non-alcoholic fatty liver disease (NAFLD) in overweight/obese children who visit a hospital, and to explore the influencing factors of NAFLD, in order to provide a basis for the prevention of NAFLD in overweight/obese children.

Methods: Overweight/obese children who visited Hunan Children's Hospital from June 2019 to September 2021 were recruited. The prevalence rate of NAFLD was examined.

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Objective: To evaluate the predictive performance of anthropometric indices for metabolic syndrome (MetS) among Chinese adolescents with different nutritional status.

Methods: We recruited 9,513 adolescents aged 10-18 years from seven provinces in China during September 2014. Anthropometric indices and blood pressure were measured at recruitment, and blood samples were collected for determining fasting plasma glucose and lipid profile.

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Background: The prevalence of metabolic syndrome (MetS) rapidly increased over the past decades. However, little evidence exists about the effects of long-term exposure to ambient air pollution on MetS in children and adolescents.

Objective: This study aims to assess the association between long-term ambient air pollution and the prevalence of MetS in a large population of Chinese children and adolescents.

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Article Synopsis
  • Previous research suggests green spaces can positively impact health, but studies on how school greenness affects children's obesity are limited.
  • This study examined the relationship between greenery around schools and body fat in over 56,000 Chinese children aged 6-18 using satellite data.
  • Findings indicated that increased school greenness was linked to lower body mass index (BMI) and waist circumference, with air pollution partially influencing this connection, but physical activity did not show a significant mediating effect.*
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Background: In this research, an meta-analysis was performed for assessment of the associations between O6-methyguanine-DNA methyltransferase (MGMT) promoter hypermethylation possessing low-grade intraepithelial lesion (LSIL), high-grade intraepithelial lesion (HSIL), cervical cancer (CC), and clinicopathological characters of CC.

Methods: Literature selection were conducted through searching PubMed, Web of science, EMBASE, China National Knowledge Infrastructure and Wanfang databases (up to November 2018). An assessment of associations between MGMT methylation and LSIL, HSIL, CC risk and clinicopathological characteristics was performed through pooled odds ratios (ORs) with relevant 95% confidence intervals (CIs).

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Objective: To explore the willingness of care and related influencing factors among caregivers of those 'left at hometown' children under 7 years in Chinese rural areas.

Methods: Questionnaires were used to survey caregivers (n = 7585) who were identified by multi-stage stratified cluster sampling. Multi-factor ordinal logistic regression analysis was used to screen the influencing factors on the willingness of care among them.

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Objective: To explore the influences of guardians on emotion and behavior of rural left-behind children aged 3 to 7 years.

Methods: A self-designed questionnaire of children's condition and Children Strengths and Difficulties Questionnaire (the edition for parents, SDQ) were used to investigate 805 left-behind children aged 3 to 7 years in countryside.

Results: The prevalence of difficulty among left-behind children was 3.

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Objective: To explore the genetic and environmental factors related to the development of polydactyly and syndactyly, and to provide evidence for prevention on birth defects.

Methods: A hospital-based case-control study was conducted. 111 cases and 222 controls were interviewed with standardized questionnaires.

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Objective: To explore knowledge, attitude, practice (KAP) and related determinants on nutrition among caregivers of those rural stranded children under 7 years of age in China and to provide evidence for setting up relevant health education program.

Methods: 1691 caregivers of the stranded children randomly selected were surveyed by a standard questionnaire. Logistic regression models were used to screen the determinants on KAP regarding nutrition.

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Objective: To understand emotional, behavioral problems and related determinants among rural stranded children and to provide evidence for further psychological support.

Methods: A total of 3944 caregivers of children in the rural areas and aged 4 to 7 years but without parents around, were randomly selected. Data were collected through Strengths and Difficulties Questionnaires (the edition for parents, SDQ).

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Objective: To explore the nutritional status and determinants among rural stranded children under 7 years of age.

Methods: The group of stranded children (n=7585) and the children for control (n=7557) were identified by multi-stage stratified cluster sampling. The ascertainment methods mainly included questionnaire, anthropometric measurements and laboratory examination.

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Objective: To provide evidence for setting up violence intervention programs in rural middle schools, through studying the influential factors.

Methods: Taking variables including emotional, physical and sexual violence in the past year as the multi-dependent variables before multivariate multilevel model logistic regression model was adopted to analyze the correlations among the three kinds of violence and the influential factors.

Results: Among 3620 respondents, the incidence rates of emotional, physical and sexual violence weres 21.

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Objective: To understand the dietary nutrients among rural stranded children.

Methods: 2551 children aged 2 to 7, including 1278 stranded children in the rural areas and another 127 children served as controls were selected, using multistage stratified cluster random sampling. Dietary survey was performed with three-day weighing dietary method and questionnaire on food intake.

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Through analyzing the influencing factors of congenital heart disease (CHD), it is aimed to establish CHD risk prediction model in fetus, and simultaneously provide theoretical foundation for CHD prevention. One-factor logistic regression method was used to screen the significant factors regarding CHD, and to separately adopt multiple-factor non-conditional logistic regression method and decision tree to set up model prediction fetus CHD risk and to analyze the advantages and shortcomings. Correct classification rates turned to be 80.

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Objective: To understand the status on care and nutrition of children living in the rural areas (so called 'left-behind' children) while their parents were seeking for jobs in the urban areas.

Methods: Cross-sectional study was employed in this investigation. The group of 'left-behind' children (n = 774) and the comparison group (n = 774) were identified.

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Objective: To evaluate the abilities of population-based birth defects surveillance system (PBBDSS) and hospital-based birth defects surveillance system(HBBDSS).

Methods: We used capture-mark-recapture method(CMR) to analyze the data of the two kinds of birth defects surveillance systems from 1 Oct. 2006 to 31 Dec.

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