Publications by authors named "Jia Y Liang"

Article Synopsis
  • Research on patients with Congestive Heart Failure (CHF) and chronic obstructive pulmonary disease (COPD) in ICU settings has not thoroughly determined the ideal blood pressure (BP) level for these individuals.
  • A study analyzed data from 6,309 ICU patients to explore how systolic blood pressure (SBP) relates to in-hospital mortality, using complex statistical methods.
  • Findings revealed an L-shaped relationship between SBP and mortality risk, with significant implications for care, particularly noting an inflection point at around 99.5 mmHg where risk changes.
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  • Elevated red blood cell distribution width (RDW) is linked to higher in-hospital mortality rates in patients with congestive heart failure (CHF) who also have diabetes mellitus (DM).
  • A study analyzing 7,063 patients found that a 1 g/L rise in RDW correlates with a 9% increase in mortality risk, highlighting the dangerous implications of increased RDW levels.
  • The research supports a clear connection between RDW levels and in-hospital mortality, emphasizing the need for monitoring RDW in ICU patients suffering from both conditions.
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  • Previous research indicated a notable link between serum calcium levels and mortality in ICU patients, particularly those with diabetes and congestive heart failure (CHF).
  • This study evaluated 7,063 patients using the MIMIC-IV database, finding an in-hospital mortality rate of 12.2% and established a U-shaped relationship between serum calcium levels and mortality.
  • The analysis identified a critical inflection point at 9.05 mg/dL, revealing that both low and high serum calcium levels are associated with increased in-hospital mortality in patients with diabetes and CHF.
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Objectives: Mask adherence continues to be a critical public health measure to prevent transmission of aerosol pathogens, such as SARS-CoV-2. We aimed to develop and deploy a computer vision algorithm to provide real-time feedback of mask wearing among staff in a hospital.

Design: Single-site, observational cohort study.

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  • Glycemic control remains crucial for diabetes management, primarily achieved through adjusting insulin doses, using both long-acting for daily needs and short-acting for meal-related spikes.
  • Blood glucose monitoring and carbohydrate counting can be burdensome for users, impacting their adherence to insulin therapy.
  • A new smartphone-based system utilizing computer vision simplifies this process by detecting food carbohydrate loads from images, and combined with blood glucose data, it calculates necessary insulin doses, potentially revolutionizing diabetes care.*
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Implantable and ingestible biomedical electronic devices can be useful tools for detecting physiological and pathophysiological signals, and providing treatments that cannot be done externally. However, one major challenge in the development of these devices is the limited lifetime of their power sources. The state-of-the-art of powering technologies for implantable and ingestible electronics is reviewed here.

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Overactive bladder (OAB) is a common condition that affects a significant patient population. The N-methyl-D-aspartate receptor (NMDAR) has a role in developing bladder overactivity, pharmacological inhibition of which inhibits bladder overactivity. The common pathogenesis of OAB involves bladder smooth muscle (BSM) overactivity.

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Background: We investigated the diversity and behaviour of insects that visit flowers of four native (Family Melastomataceae) species of Taiwan and a horticultural hybrid species at the Fushan Botanical Garden, Taiwan biweekly from May to August 2020. Visits of flower-visiting insects were classified into seven behavioural categories, based on the insects' behaviour and positions on the flower. The data are further assigned into four insect-flower interactions, namely pollination, herbivory, commensalism and neutralism.

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Epithelial adherens junctions (AJs) and tight junctions (TJs) undergo disassembly and reassembly during morphogenesis and pathological states. The membrane-cytoskeleton interface plays a crucial role in junctional reorganization. Protein 4.

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In this work, sodium salicylate and ethylenediamine (EDA) are used as the precursors to synthesize green fluorescent carbon dots (CDs). The CDs have some attractive properties, including better oxidation resistance, good water solubility, and excellent stability in high ionic strength solutions in a pH range of 6.0-10.

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Sensitive and selective determination of mercury ion (Hg) is critical for human health and environmental monitoring. Herein we construct an effective ratiometric fluorescent sensing platform by combining green fluorescent polymer carbon dots (PCDs) and red fluorescent tetraphenylporphyrin tetrasulfonic acid hydrate (TPPS) for specific and visual detection of Hg. The fluorescence of PCDs can be quenched by TPPS through inner filter effect (IEF).

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Hematin is an oxidized form of heme, and the abnormal levels of hematin in the human body can lead to various inflammatory lesions. Hence, there is still a need to establish a rapid, sensitive and efficient method for hematin detection. Herein, the green fluorescent carbon quantum dots (CQDs) are synthesized by using L-cysteine and hydrogen peroxide as precursors.

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The Red-emitting nitrogen-doped carbon dots (N-CDs) are synthesized using o-phenylenediamine by a one-step method, and can serve as a fluorescent probe for "turn off" detection of hematin in human red cells. The red-emitting N-CDs can be obtained only in acidic conditions and the emission of the red-emitting N-CDs is pH-dependent, indicating proton-controlled synthesis and emission. The red-emitting N-CDs are 2.

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Being a common hazardous waste, 4-nitrophenol (4-NP) has caused a serious threat to humans and environment. Therefore, rapid and selective detection of 4-NP, especially using a simple and portable instrument, is highly desired for human health and environmental monitoring. Herein, we develop a novel pH-mediated reversible fluorescence nanoswitch for selectively detecting 4-NP by using water-soluble fluorescent polymer carbon dots (PCDs) as a probe.

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