Optimized strategy for schistosomiasis elimination: results from marginal benefit modeling.

Background: Poverty contributes to the transmission of schistosomiasis via multiple pathways, with the insufficiency of appropriate interventions being a crucial factor. The aim of this article is to provide more economical and feasible intervention measures for endemic areas with varying levels of poverty.

Methods: We collected and analyzed the prevalence patterns along with the cost of control measures in 11 counties over the last 20 years in China.

Cost-effectiveness analysis of the integrated control strategy for schistosomiasis japonica in a lake region of China: a case study.

Background: Schistosomiasis japonica remains an important public health concern due to its potential to cause severe outcomes and long-term sequelae. An integrated control strategy implemented in the Peoples' Republic of China has been shown to be effective to control or interrupt the transmission of schistosomiasis. The objective of this study is to estimate the disease burden of schistosomiasis and assess the cost-effectiveness of the integrated control strategy focused on different major interventions at three stages for schistosomiasis control in a lake setting, to provide reference for policy making or planning.

[Epidemiological characteristics of echinococcosis death cases in China from 2008 to 2016].

Objective: To understand the epidemiological characteristics of death cases of echinococcosis in China from 2008 to 2016, so as to provide an important reference for the prevention and control of echinococcosis.

Methods: The death information registration and management system data were selected to analyze the epidemiological characteristics of the death cases of echinococcosis. The data were analyzed by SPSS 21.

[Global burden and challenges of parasitic diseases in Africa].

Parasitic diseases are common infectious diseases closely related to poverty, which are mainly endemic in the tropical and subtropical regions. Africa is the major epidemic area of parasitic diseases, and the global burden of malaria and schistosomiasis is over 85% in Africa. This paper reviews the disease burden, regional distribution and control strategies of the main parasitic diseases in Africa, in order to promote the prevention and control of parasitic diseases in this area.

[Academic influence of institutes in field of schistosomiasis control and research in China].

Objective: To assess the academic influence of schistosomiasis control and research institutions in China.

Methods: The papers (including original articles and reviews) pertaining to schistosomiasis in Science Citation Index Expanded (SCIE) of Web of Science (WOS) during the period from 2002 to 2012 were searched. The number of published papers, h index and citation frequencies of the papers of Chinese institutes and authors were analyzed by a bibliometric method, and the academic influences of the institutes and authors were assessed according to the number of published papers and h index.

[Assessment on the effect of joint effort for schistosomiasis control in Hubei Province].

Objective: To analyze the progress of implementation of integrated strategy with emphasis on the control of infectious sources and effectiveness for joint-project of schistosomiasis control in Hubei province.

Methods: Data on the endemic status and implementation of each integrated intervention in 6 collaborated counties including Gongan, Hanchuan, Honghu, Jiangling, Xiantao and Yangxin during 2009-2013 were collected and analyzed. 18 administrative villages with a history of endemic schistosomisis from 6 counties were selected for field survey.

Eco-social determinants of Schistosoma japonicum infection supported by multi-level modelling in Eryuan county, People's Republic of China.

Schistosomiasis remains of considerable public health concern in many tropical and subtropical regions of the world, including the People's Republic of China (P.R. China).

[Field evaluation of a novel plant molluscicide "Luo-wei" against Oncomelania hupensis IV molluscicidal effect in field of river beach in Dongzhi County, Anhui Province].

Objective: To evaluate the field effect of the plant molluscicide "Luo-wei" (tea-seed distilled saponins, TDS) against the snail Oncomelania hupensis in the river beach in Anhui Province.

Methods: The immersing and spraying experiments were carried out in the river beach in Dongzhi County, Anhui Province, to assess the molluscicidal effect of 4% TDS comparing with 50% wettable powder of niclosamide ethanolamine salt (WPN). The chi(2) test or Fish's exact test was used to examine the differences between or among the molluscicidal effects by different environments, molluscicides, application methods, or days after the intervention.

[Effect of a novel plant molluscicide "Luo-wei" against Oncomelania hupensis in plateau mountain areas].

Objective: To evaluate the effect of a novel plant molluscicide, 4%"Luo-wei" (Tea-seed distilled saponins, TDS) against Oncomelania hupensis snails in plateau mountain areas in Yunnan Province.

Methods: The immersing and spraying experiments were carried out in the ditches and grassland of Xiaolian Administrative Village in Heqing County, Yunnan Province, to assess the molluscicidal effect of 4% TDS comparing with 50% wettable powder of niclosamide ethanolamine salt (WPN) in different environments and time.

Results: After immersion for 24, 48 h and 72 h, the snail death rates were 70.

[Field evaluation of a novel plant molluscicide "Luo-wei" against the snail Oncomelania hupensis III molluscicidal effect by spraying method in hilly regions].

Objective: To evaluate the molluscicidal effect of a novel plant molluscicide "Luo-wei" (Tea-seed distilled saponins, TDS) against Oncomelania httpensis in billy regions.

Methods: The molluscicidal effect of TDS at a dose of 5 g/m2 by the spraying method against Oncomelania snails was assessed in a setting with a high snail density in Husban Village, Jiangning District of Nanjing City, and the effect was compared with that of 50% wettable powder of niclosamide ethanolamine salt (WPN) at a dose of 2 gIm2 at different time after spraying.

Results: Afterl, 3, 7 and 15 day (days) of the spraying experiment, the snail death rates of the TDS group were 56.

[Field evaluation of a novel plant molluscicide "Luo-wei" against Oncomelania hupensis snails II molluscicidal effect in the field of lake areas in Hanchuan City, Hubei Province].

Objective: To evaluate the effect of a novel plant molluscicide "Luo-wei" (Tea-seed distilled saponins, TDS) against Oncomelania hupensis in the field of lake areas in Hanchuan City, Hubei Province.

Methods: Immersing experiment and spraying experiment were carried out in 5 ditches and a beach land respectively in Hanchuan City, Hubei Province to compare the molluscicidal effects among 4% TDS, 50% wettable powder of niclosamide ethanolamine salt (WPN), and 26% suspension concentrate of metaldehyde and niclosamide (MNSC) by different dosages and time. The chi2 test or Fish's exact test was used to examine the differences of snail death rates among them.

[Establishment and application of rapid assessment system of environment with high transmission risk of schistosomiasis in marshland and lake regions II establishment and application of measures for field survey].

Objective: To establish the measures of schistosomiasis field survey and evaluate the efficacy of their application according to the content of indexes of rapid assessment system to high transmission risks in schistosomiasis endemic areas of lake regions.

Methods: In 2012, based on the analysis of Oncomelania hupensis snail situation, and schistosomiasis epidemic data of human and cattle from 2008-2010, 60 villages from Hunan, Hubei, Jiangxi and Anhui provinces were selected and investigated, and the content of the investigation included the field feces, snail status, and epidemic situation of human and cattle. The systemic sampling was applied for snail investigation; the feces collected from snail investigation field were examined by the hatching test (3 bottles for 1 sample).

[Assessing the correlation between international collaboration and academic influence in parasitic diseases: a case study of National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention].

Objective: To investigate the activity of scientific research and international collaboration in National Institute of Parasitic Diseases (NIPD), Chinese Center for Disease Control and Prevention (China CDC) from 2002 to 2012, and assess the relationship between international collaboration and academic influence at an individual level.

Methods: Non-bibliometric indicators including number and structure of scientific research personnel, number of projects and funds, visiting frequency, etc, were used to assess the activity of scientific research and international collaboration, and bibliometric indicators including publications and h index, were employed to estimate the academic influence of senior professionals in NIPD, China CDC. The relationship between the international collaboration and international academic influence in the control and research of parasitic diseases was evaluated by using analysis of covariance and generalized linear models.

[Field evaluation of a novel plant molluscicide "Luo-Wei" against Oncomelania hupensis I molluscicidal effect by the spraying method in lake and marshland regions].

Objective: To evaluate the field effect of a novel plant molluscicide "Luo-wei" (Tea-seed distilled saponins, TDS) against Oncomelania hupensis in the lake and marshland regions.

Methods: A spraying experiment was carried out in the grassland of two schistosomiasis endemic counties, including Xingzi in Jiangxi Province and the Huarong in Hunan Province, to assess the molluscicidal effect of 4% TDS comparing with 50% wettable powder of niclosamide ethanolamine salt (WPN). The chi2 test was used to examine the differences between regions, molluscicides, or days after spraying.

[Effect of ecological civilized homestead construction on schistosomiasis control].

Objective: To evaluate the effect of Ecological Civilized Homestead Construction on schistosomiasis control.

Methods: The data of ecological civilized homestead construction and schistosomiasis control were collected and analyzed in Meiwan Village, Shuangqiao Town, Danling County, Sichuan Province from 2004 to 2010.

Results: Ecological Civilized Homestead Construction was carried out from 2004 to 2010.

[Establishment and application of spatio-temporal model of schistosomiasis japonica in a county in marshland region].

Objective: To develop a spatio-temporal model of schistosomiasis japonica based on Bayesian model, and to analyze the spatio-temporal pattern of schistosomiasis, as well as to evaluate the impact of environment changes on schistosomiasis endemic.

Methods: Different Bayesian models were established by employing the data of the periodical surveillance on schistosomiasis during 1996-2005 period by taking into account of the uncertainty in sensitivity and specificity of diagnostic test, then the best fitness model was selected to analyze the spatio-temporal pattern of schistosomiasis and evaluate the impact of environment changes on schistosomiasis.

Results: The model with space-time interaction was a better fitting model.

Soil-transmitted helminth reinfection after drug treatment: a systematic review and meta-analysis.

Background: Soil-transmitted helminth (STH) infections (i.e., Ascaris lumbricoides, hookworm, and Trichuris trichiura) affect more than a billion people.

[Risk factors of schistosomiasis transmission in marshland and lake regions in midstream of Yangtze River].

Objective: To study the risk factors of schistosomiasis related to household economic condition and individual behavior in marshland and lake regions, so as to provide evidences for schistosomiasis control.

Methods: Six villages were sampled with the stratified cluster sampling method, 2 339 villagers from 1 247 households were surveyed by a questionnaire and meanwhile their sera were assayed for schistosomiasis by IHA. The Logistic regression was used to analyze the relationship between the results of serological examinations and risk factors.

[Burden of disease in schistosomiasis japonica III household socioeconomic determinants of chronic schistosomiasis].

Objective: To explore the socioeconomic determinants of chronic schistosomiasis japonica at household level.

Methods: The socioeconomic status of case and control families in lake and marsh schistosomiasis endemic areas were investigated by questionnaire, socioeconomic factors were analyzed by the principle components analysis, and the wealth index were calculated to evaluate the economic status at household level. Then the relation between schistosome infection and some influencing factors were analyzed by two-level Logistic regression model.