Publications by authors named "Jia Li Han"

Article Synopsis
  • Radiotherapy for pelvic cancers relies on accurately defining clinical target volumes (CTV), particularly for the inguinal lymphatic drainage region, to enhance treatment effectiveness.
  • This study utilized F-FDG PET/CT scans to identify the patterns of lymph node metastases (LNM) in the groin area of patients with pelvic malignancies, providing specific measurements for optimal CTV delineation.
  • Results indicated that LNM distribution varies around the femoral artery, leading to specific distance recommendations for CTV margins to cover 95% of LNM, aiming to improve disease control in radiation therapy.
View Article and Find Full Text PDF

This manuscript offers a comprehensive overview of nanotechnology's impact on the solubility and bioavailability of poorly soluble drugs, with a focus on BCS Class II and IV drugs. We explore various nanoscale drug delivery systems (NDDSs), including lipid-based, polymer-based, nanoemulsions, nanogels, and inorganic carriers. These systems offer improved drug efficacy, targeting, and reduced side effects.

View Article and Find Full Text PDF

Objective: Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), shares clinical and immunological features with psoriasis. Genome-wide association studies have found common susceptibility genes. However, epidemiologic data evaluating the association between psoriasis, psoriatic arthritis and risk of IBD are sparse.

View Article and Find Full Text PDF

Objective: To evaluate the expression of galectin-3 and galectin-9 in mice nasal mucosa,and to explore the role of galectin-3 and galectin-9 in allergic rhinitis (AR).

Methods: Twenty mice were randomly divided into AR group and control group, 10 mice in each group. Ten mice of BALB/c were sensitized intraperitoneally with 10 microg of ovalbumin(OVA) adsorbed onto 2 mg Al(OH)3 on day 1 and day 14.

View Article and Find Full Text PDF