Successful use of remimazolam combined with remifentanil for painless gastroscopy in a patient with morbid obesity: a case report.

Backgroud: In recent years, as the number of people with obesity has surged, the number of morbidly obese patients has also grown. The pathophysiological changes in morbid obesity can lead to combined lung diseases, which may result in hypoventilation, hypoxemia, acute upper airway obstruction, acute respiratory distress syndrome, and sleep apnea syndrome, posing serious challenges to anesthesia management. Here, we describe a case of the administration of remimazolam combined with remifentanil in a patient with morbid obesity undergoing gastroscopy.

Large isolated fibrous tumors in the upper esophagus: A case report.

Background: Solitary fibrous tumors (SFT) are rare spindle cell tumors that are usually benign. A total of 10 cases of SFTs in the upper esophagus have ever been reported. Here, we report the anesthetic management of a patient with a large isolated fibrous tumor of the upper esophagus compressing the tracheal membrane.

Successful remimazolam sedation-epidural block in an older patient with severe chronic obstructive pulmonary disease: A case report.

Background: Chronic obstructive pulmonary disease (COPD) is associated with high morbidity and mortality rates worldwide. Older patients have a degenerative cardiopulmonary function, weak compensatory capacity, and poor surgical tolerance. Therefore, the mode of anesthesia must be optimized.

Hyperlactemia associated with secondary hepatocellular carcinoma resection in relation to circulation stability and quality of recovery: A case report.

Background: Intraoperative hyperlactatemia often affects circulatory stability, vital organ function, and postoperative recovery, poses a serious prognostic risk, and requires considerable attention from anesthesiologists. Here, we describe a case of hyperlactatemia during the postoperative resection of liver metastases after chemotherapy for sigmoid colon cancer. This did not affect the patient's circulatory stability or quality of awakening, which is rarely reported in clinical practice.

The interaction of MC3R and MC4R with MRAP2a in rainbow trout (Oncorhynchus mykiss).

Melanocortin 3 and 4 receptors are two important neural G protein-coupled receptors that regulate energy homeostasis in vertebrates. Melanocortin receptor accessory protein 2 (MRAP2) is also involved in the regulation of food intake and body weight as a variable regulator of melanocortin receptors. Rainbow trout (Oncorhynchus mykiss) is a valuable cold-water fish cultured worldwide.

Numerical Investigation of the Thermal Behavior of Cracked RP-3 in Rectangular Cooling Channels under Different Inclinations.

The pyrolysis effect of aviation kerosene is common in the regenerative cooling process of hypersonic aircraft scramjets. To find out the effect of inclination variation on the characteristics of aviation kerosene RP-3 considering thermal cracking in a regenerative cooling rectangular channel, a detailed chemical mechanism of RP-3 pyrolysis is introduced to construct a numerical model. The results indicate that the pyrolytic reaction begins at the junction of the heating wall and the side walls, and the main products of pyrolysis are light olefins and alkanes.

Molecular cloning, tissue distribution, and pharmacologic function of melanocortin-3 receptor in common carp (Cyprinus carpio).

Melanocortin-3 receptor (MC3R) not only regulates energy homeostasis in animals, but also is an important regulator of inflammation. As one of the most widely farmed freshwater fish, common carp has attracted great interest for its feeding and inflammation regulation. In this study, we cloned the coding sequence (CDS) of common carp Mc3r (ccMc3r), examined its tissue expression profile, and investigated the function of this receptor in mediating downstream signaling pathways.

The functional microbiota of on- and off-year moso bamboo (Phyllostachys edulis) influences the development of the bamboo pest Pantana phyllostachysae.

Background: Development of Pantana phyllostachysae, a moso bamboo pest, is affected by its diet. Understanding the mechanism underlying the different insect-resistant capacities of on- and off-year moso bamboo fed by P. phyllostachysae is crucial for managing pest outbreaks.

Prevalence of strabismus among preschool children in eastern China and comparison at a 5-year interval: a population-based cross-sectional study.

Objective: To update data on strabismus and evaluate the changes in prevalence and patterns among preschoolers in eastern China over a period of 5 years.

Design: Nanjing Eye Study, a longitudinal population-based study.

Setting: Recruitment and testing in kindergartens in Yuhuatai District, Nanjing.

Development of a Chemical-Kinetic Mechanism of a Four-Component Surrogate Fuel for RP-3 Kerosene.

RP-3 kerosene is the most widely used aviation kerosene in China, and research on its chemical-kinetic mechanism is significant for understanding the combustion characteristics. Based on a novel four-component surrogate fuel consisting of -dodecane, 2,5-dimethylhexane, 1,3,5-trimethylbenzene, and decalin (54, 22, 14, and 10% by mole), the detailed chemical-kinetic mechanism of the corresponding RP-3 surrogate fuel with 1333 species and 6803 reactions has been developed and then reduced to 145 species and 818 reactions for high-temperature conditions. After that, the merged surrogate mechanism of surrogate fuel was validated by various experimental data sets for each individual surrogate component.

DMST-H2 Promotes Recovery in Mice with Antibiotic-Associated Diarrhea.

Antibiotic-associated diarrhea (AAD) is the most common side effect of antibiotics and is routinely treated with probiotics in clinical. , extensively utilized for producing dairy foods, has recently been regarded as a new promising probiotic candidate. In this study, the efficacy of DMST-H2 (DMST-H2) for AAD treatment in mice was investigated.

Irregular Bone Defect Repair Using Tissue-Engineered Periosteum in a Rabbit Model.

Background: In previous studies, we succeeded in repairing a long bone defect with tissue-engineered periosteum (TEP), fabricated by incorporating rabbit mesenchymal stem cells with small intestinal submucosa. In this study, we investigated the feasibility of allogeneic irregular bone defect repair using TEP.

Methods: We performed a subtotal resection of the scapula in 36 rabbits to establish a large irregular bone defect model.

Structural characterization of a novel Fr. polysaccharide and its immunity activity in BALB/c mice.

Fr. has been regarded as a great edible medicinal fungal resource in China. In this study, Fr.

Tuberculosis relapse is more common than reinfection in Beijing, China.

Background: Recurrent tuberculosis (TB) is a major health problem in countries with a high TB burden. It is very necessary to elucidate the situation of recurrent TB in Beijing, capital of China.

Objective: To determine the proportion of recurrent tuberculosis (TB) cases and to identify relapsed or reinfected cases, as well as risk factors associated with recurrence in Beijing.

Embedded system for road damage detection by deep convolutional neural network.

Road pavement could be damaged due to various reasons, causing damages such as cracks and pits. These damages cause potential dangers in traffic safety. It is necessary for road maintenance departments to find damages in time before maintenance.

Molecular Dynamics Simulation of Heat Transport through Solid-Liquid Interface during Argon Droplet Evaporation on Heated Substrates.

This paper presents a series of molecular dynamics simulations of the evaporating process of an argon droplet on heated substrates and the energy transport mechanism through the solid-liquid interface. Results indicate that the mass density through the liquid-vapor interface decreases sharply when the evaporation is in the steady state. Meanwhile, there is an adsorption layer in the form of clusters at the solid-liquid interface, which has a higher mass density than the droplet inside.

Apgar score and reduced vision in children aged 3 to 6 years.

Purpose: We aimed to examine the association between the 5-min Apgar score and reduced vision in children 3 to 6 years of age.

Methods: A total of 5834 preschool children aged 3 to 6 years participated in this school-based eye survey. Reduced vision was defined as unaided distance vision of 6/12 or worse in the better-seeing eye.

Epidemiology of Intermittent Exotropia in Preschool Children in China.

Purpose: To determine the prevalence, subtypes, and associated risk factors for intermittent exotropia (IXT) in preschool children aged 3 to 6 years in eastern China.

Methods: A population-based study including 5831 preschool children aged 3 to 6 years was conducted from 2011 to 2012 in Yuhua District, Nanjing, China, using an age-stratified random sampling procedure. Clinical examinations including ocular alignment, ocular motility, visual acuity, prism cover test, cycloplegia refraction, stereopsis screening, slitlamp examination, and fundus examination were performed by trained ophthalmologists and optometrists.

[Study on alkaloids of Corydalis ochotensis and their antitumor bioactivity].

Objective: To investigate the chemical constituents of Corydalis ochotensis and their antitumor bioactivity.

Methods: The compounds were isolated by silica gel column chromatography and recrystallization. Their structures were identified by spectroscopic analysis (NMR) and physicochemical properties.

Association between childhood strabismus and refractive error in Chinese preschool children.

Purpose: To investigate the association between concomitant esotropia or concomitant exotropia and refractive error in preschool children.

Methods: A population-based sample of 5831 children aged 3 to 6 years was selected from all kindergartens in a representative county (Yuhuatai District, Nanjing, Jiangsu Province) of Nanjing, China. Clinical examinations including ocular alignment, ocular motility, visual acuity, optometry, stereopsis screening, slit lamp examination and fundus examination were performed by trained ophthalmologists and optometrists.

[Effect of miR-202 on the growth of multiple myeloma cells via regulating B cell-activating factor and the underlying mechanism].

Objective: To explore the regulating effect of miR-202 on B cell-activating factor, and check whether the regulation influences the growth of multiple myeloma cells.

Methods: The potential binding sites of BAFF for miR-202 were predicted using bioinformatics software. Luciferase reporter gene analysis was used to evaluate the regulatory effect of miR-202 on BAFF.

[Study on early detection of gray mold on tomato leaves using hyperspectral imaging technique].

The present paper put forward the technology route for feature images extraction of grey mold sick on tomato leaves based on SIMCA--combination image extraction based on MLR-grey mold sick information extraction based on minimum distance method. Firstly, through the 680-740 nm band's variance image and the discrimination power parameter, the feature band images was found, then the feature bands information was used as the input of MLR analysis, and under the 0.5 accuracy threshold value, 99% accuracy was obtained, which showed the discrimination power of the features bands for grey mold sick tomato leaf detection, and using the MLR regression coefficient to extract a band combination image, and through the minimum distance method, tomato grey mold sick information was found.

[Early diagnosis of gray mold on tomato stalks based on hyperspectral data].

Early diagnosis of gray mold on tomato stalks based on hyperspectral data was studied in the present paper. A total of 112 samples' hyperspectral data were collected by hyperspectral imaging system. The study spectral region was from 400 to 1,030 nm.

[Improving degradation ability of an aerobic denitrifer by ultraviolet mutagenesis].

An aerobic denitrifier (YS) isolated from swage was mutagenized by UV-irradiation and a high-nitrogen-removal mutant (TB) was obtained. Differences between these two strains in physical and chemical properties and denitrification capacity were studied. The results showed that the denitrification capacity of mutant strains TB was improved.