With the rapid improvement of equipment integration technology, multi-spectrum detectors are integrated into compact volumes and widely used for object detection. Confront with this challenge, it is essential to propose a strategy to design a single-layer metasurface with multi-spectrum responses in microwave and infrared ranges. In this work, we proposed a method of designing meta-atoms, which is capable of achieving functional electromagnetic response at microwave and infrared individually.
View Article and Find Full Text PDFCertain insecticides are known to have estrogenic effects by activating estrogen receptors through genomic transcription. This has led researchers to associate specific insecticide use with an increased breast cancer risk. However, it is unclear if estrogen receptor-dependent pathways are the only way in which these compounds induce carcinogenic effects.
View Article and Find Full Text PDFMicroRNAs (miRNAs) are major players in cellular responses to xenobiotic compounds and toxins. However, the role of miRNAs in pyrethroid pesticide-induced cancer progression remains unclear. This study aimed to investigate the function of miR-96-5p in permethrin-induced proliferation and migration in breast cancer cells.
View Article and Find Full Text PDFThe effect of magnetism on the thermoelectric (TE) transformation efficiency has recently attracted a lot of attention. A CrI monolayer is a two-dimensional (2D) ferromagnetic (FM) semiconductor with a Curie temperature of 45 K. In this work, we employed first-principles calculations within the framework of density functional theory (DFT) combined with the non-equilibrium Green's function (NEGF) method and Landauer-Buttiker theory to study the effect of magnetism on the TE performance of a CrI monolayer.
View Article and Find Full Text PDFJ Environ Sci Health B
February 2021
Micro RNAs (miRNAs) are major players in cellular responses to xenobiotic compounds and toxins. However, their functions in organophosphate-induced cytotoxicity remain unclear. This study investigated the involvement of miR-96-5p in the non-cholinergic toxicity of malathion in normal human kidney cells (HK-2 cells).
View Article and Find Full Text PDFTwo-dimensional (2D) layered TiC MXene has been synthesized experimentally, and the magnetism of monolayer TiC MXene has been predicted theoretically. In this study, based on first-principles calculations, five magnetic configurations of monolayer TiC were constructed to predict the magnetic ground state. We have found that the antiferromagnetic (AFM) state has the lowest energy.
View Article and Find Full Text PDFNanotechnology
December 2019
By means of density functional theory calculations, we successfully predict two stable 2D triangular borophenes, namely BH and BO. Our results indicate that BH is a Dirac material and its cone point is located at the K point of the Brillouin zone (BZ). BO is identified as having a node-line ring and Dirac cones together.
View Article and Find Full Text PDFTwo-dimensional (2D) materials with negative Poisson's ratio (NPR) attract considerable attention because of their exotic mechanical properties. We propose a new 2D material, monolayer GaPS, which shows NPR for both in-plane (-0.033) and out-of-plane (-0.
View Article and Find Full Text PDFTwo-dimensional materials with high carrier mobility and tunable magnetism are in high demand for nanoelectronic and spintronic applications. Herein, we predict a novel two-dimensional monolayer KTlO that possesses an indirect band gap of 2.25 eV (based on HSE06 calculations) and high carrier mobility (450 cm2 V-1 s-1 for electrons and 160 cm2 V-1 s-1 for holes) by means of ab initio calculations.
View Article and Find Full Text PDFBiomed Pharmacother
December 2018
miRNAs are crucially involved in cellular responses to exotic chemical toxins. However, the role of miRNAs in organophosphates induced cytotoxicity is poorly understood. In present study, we investigated the role of miR-513a-5p in dichlorvos induced cytotoxicity in human kidney cell line HK-2.
View Article and Find Full Text PDFAlternative splicing (AS) is an important mechanism for controlling gene expression, which regulates multiple biological processes in higher organisms. Chinese indigenous Xiang pig has distinctive biological characteristics, such as small size, early sexual maturity, lower litter size and not very clear exhibition of estrous behaviors. To further understand how AS responds to estrous cycles in Xiang pig, the genome-wide analysis of AS events was performed by RNA-seq method in Xiang pig ovaries at diestrous and estrous.
View Article and Find Full Text PDFCopy number variation (CNV) is a major proportion of genetic variation, which changes the gene structure and dosage and affects gene expression and function. To validate the presence and the function of CNV in pig, we used real-time quantitative polymerase chain reaction (qPCR) method to validate a 496 kb CNV region comprising MTHFSD gene on chromosome 6 of Xiang pig detected by single nucleotide polymorphism (SNP) array. Then we investigated the distribution of the MTHFSD CNV in a total of 545 pigs in four breeds.
View Article and Find Full Text PDFResistive patch array incorporating with metallic backplane provided an effective way to achieve broadband metamaterial absorbers (MAs) in microwave frequency, and the outstanding construction contributed more flexible and diversified broadband absorption. In this paper, we attempted to load metallic resonators (MRs) to three-dimensional resistive MA to further enhance the lower-frequency absorption performance. Simulation showed that the partial absorption peak was separated to the lower frequency, while the rest of broadband absorption was unaffected.
View Article and Find Full Text PDFPlatelet hyperactivity plays an important role in arterial thrombosis and atherosclerosis. The present study was aimed to investigate the effects of different extracts of propolis and components of flavonoids on platelet aggregation. Platelet-rich plasma was prepared and incubated in vitro with different concentrations of the tested extracts and components of flavonoids.
View Article and Find Full Text PDFTo further understand the role of microRNA (miRNA) during testicular development, we constructed four small RNA libraries from the testes of the Chinese indigenous Xiang pig at four different ages, which were sequenced using high-throughput Solexa deep sequencing methods. It yielded over 23 million high-quality reads and 1,342,579 unique sequences. At two and three months of age, the proportion which represented miRNAs was the most abundant class of small RNAs, but it was gradually replaced by the category that represented piRNAs in adult testes.
View Article and Find Full Text PDFDichlorvos (DIC) is an organophosphate compound with cholinergic and noncholinergic neurotoxicity as well as non-neuronal cytotoxicity. Little is known about the mechanisms of DIC cytotoxicity in non-neuronal cells. In this study, we established a porcine kidney epithelial cell line (PK15) as a model to explore the mechanisms underlying DIC cytotoxicity based on miRNA and mRNA expression profiling analysis.
View Article and Find Full Text PDFFollicle stimulating hormone (FSH) is a pituitary gonadotropin that plays a key role in the regulation of gonadal function in mammal. The gonadotropic hormones are composed of two subunits, the common alpha subunit and the hormone-specific beta subunit, which determine the binding to specific receptors and induction of biological response. The aim of this study was to investigate the polymorphism of the first intron of FSH-beta gene present in different pig breeds and its influence on the expression of FSH-beta gene.
View Article and Find Full Text PDFTo augment the immunogenicity of the subunit B of Shiga toxin (Stx2e B) produced by Escherichia coli and protect piglets from edema disease in china, a fusion gene was constructed consisting of Stx2e B genetically linked at the N-terminus of the B subunit of heat-labile enterotoxin (LTB) in a translational fusion. After being induced with IPTG, the expressed fusion protein of Stx2e B-LTB was about 8.8% of total proteins, approximately 13 microg/ml of the bacteria culture.
View Article and Find Full Text PDFSheng Li Xue Bao
June 2006
Growth of animal is largely regulated by growth hormone (GH). In this study, the GH gene was isolated and cloned from the genomic DNA library from Rongjiang pig, a Chinese local swine, using polymerase chain reaction technique. The complete nucleotide sequence of a 1.
View Article and Find Full Text PDFMicroRNAs (miRNAs) are present in both plant and animal kingdoms and represents a growing family of non-coding RNAs. These tiny RNAs act as small guides and direct negative regulations usually in the process of development through sequence complementarity to target mRNAs. Although a large number of miRNAs have been identified from various animals, so far plant miRNA studies have focused mainly on Arabidopsis.
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