Effectiveness of a Four-Stage Death Education Model Based on Constructivist Learning Theory for Trainee Nursing Students.

Objective: To explore the effectiveness of the four-step death education model based on constructivist learning theory in enhancing the death coping abilities and attitudes of trainee nurses and improving course satisfaction.

Methods: Sixty-six trainee nurses from a tumour hospital in Shanxi Province were selected as the study subjects, and a class-experimental research design was adopted, in which the nursing students before the course implementation were taken as the control group and those after the course implementation were taken as the experimental group. Death Attitude Profile Revised Scale (DAP) was used to measure the cognitive attitude of nursing students towards death, and a self-made questionnaire was used to test the satisfaction of nursing students with the curriculum design.

LILRB3 genetic variation is associated with kidney transplant failure in African American recipients.

African American (AA) kidney transplant recipients exhibit a higher rate of graft loss compared with other racial and ethnic populations, highlighting the need to identify causative factors. Here, in the Genomics of Chronic Allograft Rejection cohort, pretransplant blood RNA sequencing revealed a cluster of four consecutive missense single-nucelotide polymorphisms (SNPs), within the leukocyte immunoglobulin-like receptor B3 (LILRB3) gene, strongly associated with death-censored graft loss. This SNP cluster (named LILRB3-4SNPs) encodes missense mutations at amino acids 617-618 proximal to a SHP1/2 phosphatase-binding immunoreceptor tyrosine-based inhibitory motif.

A single epidural administration of butorphanol combined with patient-controlled intravenous analgesia relieves postpartum contraction pain after cesarean section: A randomized clinical trial.

Background: Numerous studies have shown that butorphanol exerts an inhibitory effect on visceral pain. The aim of this study was to observe the effects of a single epidural administration of butorphanol combined with patient-controlled intravenous analgesia on postpartum uterine contraction pain after cesarean section.

Methods: We randomly allotted 121 women undergoing cesarean section surgery procedure to 3 groups: 31 cases were excluded; and 90 cases were divided into group S (blank control, n = 30), group I (intravenous butorphanol, n = 30), and group E (butorphanol administered into the epidural cavity, n = 30).

Research on the Enhancement of the Flotation of Low-Rank Coal Slime by Compound Collectors.

High-efficiency flotation of low-rank coal slime is an urgent problem to be solved in the comprehensive recycling and utilization of coal resources. The flotation results presented that the flotation effect of a single collector on low-rank coal slime was poor, which made it difficult to improve its flotation index. When dodecamine was added alone, the yield and ash of cleaned coal were higher at 79.

ATP-CITRATE LYASEB1 supplies materials for sporopollenin biosynthesis and microspore development in Arabidopsis.

Acetyl-CoA is the main substrate of lipid metabolism and functions as an energy source for plant development. In the cytoplasm, acetyl-CoA is mainly produced by ATP-citrate lyase (ACL), which is composed of ACLA and ACLB subunits. In this study, we isolated the restorer-4 (res4) of the thermo-sensitive genic male sterile mutant reversible male sterile-2 (rvms-2) in Arabidopsis (Arabidopsis thaliana).

Performance characterization of x-ray crystal spectroscopy highly oriented pyrolytic graphite reflectors based on x-ray diffractometry experiments.

The use of Highly Oriented Pyrolytic Graphite (HOPG) reflectors is often proposed in the design of X-ray Crystal Spectroscopy (XCS) diagnostic systems for the next-generation tokamak devices, including the ITER project. This study introduces an experimental study based on the X-Ray Diffractometry (XRD) method to evaluate the performance of HOPG reflectors. The experimental method provides both the angular responses and the reflectivities of the HOPG reflectors.

Evaluating the added value of multiparametric functional MRI in predicting renal function response to renal artery stenting in severe atherosclerotic renal artery stenosis.

Objective: To explore the potential of Intravoxel Incoherent Motion Diffusion (IVIM) and Arterial Spin Labeling (ASL) in predicting the short-term effectiveness of post-revascularization for severe atherosclerotic renal artery stenosis.

Material And Methods: A retrospective analysis of 88 cases from October 2018 to February 2023 was conducted. Patients were divided into Responder and Non-Responder groups based on renal function outcomes at their last follow-up.

Regulating Charge Distribution in Porphyrin-Based Polymer for Achieving Photocatalytic CO Conversion to CH or CH.

The photocatalytic conversion of CO into products such as CH and CH poses a significant challenge due to the lengthy reaction steps and the high energy barrier involved. In this study, both benzothiadiazole (BTD) and hydroxyl groups (-OH) are introduced into cobalt-based polymerized porphyrinic network (PPN) through a C-C coupling reaction. This modification of orbital energy levels that strengthens the ability of gain electrons and facilitates the charge transfer in PPN.

Supply chain risk transmission monitoring based on graphic evaluation and review technique.

In the supply chain context, risk events can accumulate, amplify, and mutate as they spread through the supply chain network structure. This can lead to significant losses for supply chains and global businesses. Therefore, monitoring supply chain risk is crucial to ensure the smooth operation of the supply chain.

One-step green synthesis durable flame-retardant, antibacterial and dyeable cellulose fabrics with a recyclable deep eutectic solvent.

The development of cellulose fabrics with good flame retardancy and durability has been a primary concern for in firefighting clothing. A recyclable ternary deep eutectic solvent (TDES) was used to prepare surface ammonium phosphate-modified cellulose fabrics (SACF). The incorporation of ammonium phosphate groups notably enhanced the durable flame retardancy of cellulose fabrics.

Graph pangenome reveals the regulation of malate content in blood-fleshed peach by NAC transcription factors.

Background: Fruit acidity and color are important quality attributes in peaches. Although there are some exceptions, blood-fleshed peaches typically have a sour taste. However, little is known about the genetic variations linking organic acid and color regulation in peaches.

SegRap2023: A benchmark of organs-at-risk and gross tumor volume Segmentation for Radiotherapy Planning of Nasopharyngeal Carcinoma.

Radiation therapy is a primary and effective treatment strategy for NasoPharyngeal Carcinoma (NPC). The precise delineation of Gross Tumor Volumes (GTVs) and Organs-At-Risk (OARs) is crucial in radiation treatment, directly impacting patient prognosis. Despite that deep learning has achieved remarkable performance on various medical image segmentation tasks, its performance on OARs and GTVs of NPC is still limited, and high-quality benchmark datasets on this task are highly desirable for model development and evaluation.

microRNA-875-5p-conjugated gold nanoparticles suppress breast cancer progression through the MTDH/PTEN/AKT signaling pathway.

Objective: A lack of effective delivery methods has hampered the study of therapeutics targeting miR-875-5p for breast cancer (BC).

Methods: The miR-875-5p mimic was conjugated to AuNPs to produce AuNP-miR-875-5p. Then, the effect of AuNP-miR-875-5p on the proliferative, migratory, invasive activities, and apoptosis of BC cells was detected, as well as on tumor growth in animals.

Clinicopathological Features of Epstein-Barr Virus-Positive Neuroendocrine Carcinoma: Analysis of Twenty-Two Cases.

Epstein-Barr Virus (EBV)-positive neuroendocrine carcinoma (NEC) is a rare neoplasm with limited histopathological and therapeutic data. This report presents 22 cases of EBV-positive NEC, analyzing age distribution, morphology, and immunophenotype. The median patient age was 47 years (range: 27-67 years), with a male-to-female ratio of 17:5.

Multi-Center Fetal Brain Tissue Annotation (FeTA) Challenge 2022 Results.

Segmentation is a critical step in analyzing the developing human fetal brain. There have been vast improvements in automatic segmentation methods in the past several years, and the Fetal Brain Tissue Annotation (FeTA) Challenge 2021 helped to establish an excellent standard of fetal brain segmentation. However, FeTA 2021 was a single center study, limiting real-world clinical applicability and acceptance.

Functions and mechanisms of nonstarch polysaccharides in monogastric animal production.

As natural active ingredients, polysaccharides are a class of biological macromolecules that are ubiquitous in living organisms and have antibacterial, antioxidant, antitumor and intestinal flora-regulating functions. Nonstarch polysaccharides (NSPs) are an important class of polysaccharides that include both soluble and insoluble nonstarch polysaccharides. As green feed additives, NSPs play important roles in promoting immunity and disease resistance in the body, regulating the intestinal microbial balance and improving the quality of animal products.