[Effect of Neodymium-Doped Yttrium Aluminum Garnet Laser Combined With Desensitizing Toothpaste on Dentinal Tubule Occlusion Against Acid Challenge].

Objective To assess the effects of different application sequences of neodymium-doped yttrium aluminum garnet(Nd∶YAG)laser and the desensitizing toothpaste containing stannous fluoride on dentinal tubule occlusion.Methods Twelve intact third molars freshly extracted from human were selected and prepared into dentin slices with a thickness of 0.8 mm.

The Use of 810 and 1064 nm Lasers on Dental Implants: Analysis of Temperature, Surface Alterations, and Biological Behavior in Human Gingival Fibroblasts.

The primary objective of this study was to evaluate the safety of 810 and 1064 nm laser treatment on dental implants. Peri-implantitis is a challenge for clinicians and researchers. A pig mandible model was used to evaluate temperature increases during laser irradiation.

[A Sampling Survey of the Oral Health Status and Awareness among Primary School Students in Lhasa].

Objective To investigate the oral health status and awareness of urban children in Lhasa,aiming to provide a data basis for the prevention and treatment of children's caries and the promotion of oral health education. Methods A total of 504 Tibetan students were selected by cluster sampling from 2 primary schools in Chengguan District of Lhasa.All the participants were required to take oral health examination and complete a questionnaire about oral health awareness and behavior.

Medical Emergencies in Dental Clinics: A Survey of 2013 Dentists in China.

Objective To investigate the feature and frequency of medical emergencies in dental clinics in China and the associated factors for Chinese dentists experiencing medical emergencies.Methods A survey study was conducted among 2408 dentists who attended continuing educational courses held by Society of Sedation and Analgesia of Chinese Stomatological Association in 18 cities from December 2015 to December 2018. Demographic information of the dentists and the characteristics of medical emergencies they encountered were collected and analyzed.

Advance in Functional Restoration of Injured Nerve with Low Level Laser and its Utilization in the Dental and Maxillofacial Region.

The inferior alveolar nerve and facial nerve are the two most important nerves in the dental and maxillofacial region. The injury to them is one of the major postoperative complications after alveolar surgery and orthognathic surgery. However, recovering the nerve function after injury takes a long time and the recovery effect tends to be unsatisfactory.

Multidisciplinary treatment of deep neck infection associated with descending necrotizing mediastinitis: a single-centre experience.

Objective: Deep neck infection (DNI) associated with descending necrotizing mediastinitis (DNM) is a highly lethal condition. This retrospective review was performed to share our experience performing multidisciplinary management of DNI associated with DNM during a 7-year period.

Methods: We reviewed 16 patients who had been surgically treated for DNM at Peking Union Medical College Hospital from April 2010 to July 2017.

Combined overexpression of cadherin 6, cadherin 11 and cluster of differentiation 44 is associated with lymph node metastasis and poor prognosis in oral squamous cell carcinoma.

Oral squamous cell carcinoma (OSCC) is a highly invasive lesion that frequently metastasizes to the cervical lymph nodes and is associated with a poor prognosis. Several adhesion factors, including cadherin 6 (CDH6), cadherin 11 (CDH11) and cluster of differentiation 44 (CD44), have been reported to be involved in the invasion and metastasis of multiple types of cancer. Therefore, the aim of the present study was to determine the expression of CDH6, CDH11 and CD44 in tumor tissues from patients with OSCC, and whether this was associated with the metastasis and survival of OSCC.

Types of Organ Involvement in Patients with Immunoglobulin G4-related Disease.

Background: Immunoglobulin G4-related disease (IgG4-RD) is a newly recognized systemic disease that can involve multiple organs and various clinical phenotypes. The purpose of this study was to analyze different types of organ involvement in IgG4-RD patients in China.

Methods: We conducted a prospective cohort study on IgG4-RD patients to analyze the clinical manifestations and rare features of IgG4-RD.

Efficacy of Topical Tacrolimus for Erosive Oral Lichen Planus: A Meta-analysis.

Objective: To assess the efficacy and safety of topical tacrolimus for erosive oral lichen planus (EOLP).

Methods: Literatures published up to December 2013 were searched from PubMed, Embase, CENTRAL, Chinese BioMedical Literature Database (CBM), and System for Information on Grey Literature in Europe (SIGLE). All randomized controlled trials (RCTs) of topical tacrolimus for EOLP which compared with other interventions or a placebo were considered in this Meta-analysis.

[Advances in Oral Venous Lakes].

New advances have been pioneered in the pathogenesis,clinicopathological features,and treatment of oral venous lakes. It is concluded that oral venous lakes can be classified as a venous malformation,and multidisciplinary approaches (in particular the involvement of department of dermatology and department of ear,nose and throat) may be adopted to achieve better management of this disease.

[Applications of lasers in dental implantology].

With the constant progress of laser physics, medical laser technology has been widely applied in clinical practices and basic researches. In this article, we reviewed the relevant articles on the laser applications in dental implantology and concluded that lasers provides promising solutions in the treatment technology of dental implants and in the treatment of soft and hard tissue conditions.

[The application of free tissue flap in simultaneous reconstruction of defects after tongue cancer].

Objective: To discuss the feasibility of using free tissue flap for simultaneous tongue reconstruction after tongue cancer resection.

Method: Radial forearm flaps and anterolateral thigh flaps were used for simultaneous reconstruction of different defects after tongue cancer resection in 47 cases. The functional evaluation was assessed during the follow-up period of 3 months to 9 years.

An extraoral nasoalveolar molding technique in complete unilateral cleft lip and palate.

Although nasoalveolar molding is commonly performed before cleft lip surgery, customized palatal plate availability is limited for patients far from a hospital. This case report describes a preformed extraoral nasoalveolar molding (PENAM) appliance and treatment approach for presurgical nasoalveolar molding in newborns with complete unilateral cleft lip and palate. A 12-day-old boy presented with complete unilateral cleft lip and palate.

Application of a peripheral nerve block technique in laser treatment of the entire facial skin and evaluation of its analgesic effect.

Background: The aim was to develop a technique for peripheral nerve block anesthesia (PNB) for the skin of the entire face and neck, considering the nerves anesthetized, injection sites, use of an injection method assisted by computer-controlled local anesthetic delivery (CCLAD), and to evaluate the analgesic effects of the PNB technique.

Methods: 50 patients who suffered from large nevus of Ota lesions or port-wine stains on their facial and neck skin and who required laser treatment were included. This study was designed as a non-randomized self-control trial.

[Expression of MICA/B protein in esophageal cancer and its clinical significance].

Objective: To explore the expression of MICA/B in human esophageal cancer, and to analyze its correlation with clinicopathological features.

Methods: The expression of MICA/B in 40 cases of esophagus carcinoma and corresponding normal esophageal mucosa tissues were examined by immunohistochemistry.

Results: The positive rate of expression of MICA/B protein in the esophageal carcinoma was 75.

[Effect of Yunnan Baiyao capsules on the socket healing of impacted mandibular third molar extraction].

Objective: To investigate the effect of the traditional Chinese medicine Yunan Baiyao on the socket healing of impacted mandibular third molar extraction.

Methods: A total of 200 patients requiring extractions of impacted mandibular wisdom teeth were randomized into the treatment group and the control group in a double-blinded manner, and Yunan Baiyao capsules or placebo capsules (2 g/d) were orally administered for 28 days after the operation. Dental quantitative CT scan was performed, and the volume and density of new bone at the extraction site were measured two month after operation.

Multiple coatings can improve the bond durability of one-step self-etching adhesive to primary dentin.

Objective: To investigate whether multiple coatings can improve the bond durability of one-step self-etching adhesive to primary dentin.

Methods: Twelve caries-free human primary molars were randomly divided into 2 groups. In group 1, each tooth was hemisected into 2 halves.

Effect of multiple coatings of one-step self-etching adhesive on microtensile bond strength to primary dentin.

Objective: To investigate the effect of multiple coatings of the one-step self-etching adhesive on immediate microtensile bond strength to primary dentin.

Methods: Twelve caries-free human primary molars were randomly divided into 2 groups with 6 teeth each. In group 1, each tooth was hemisected into two halves.

[Effect of combination of pulsed CO2 laser irradiation and diammine silver fluoride treatment on ultrastructure of dentine].

Objective: To explore the effect of combination of pulsed CO2 laser irradiation and diammine silver fluoride treatment on the ultrastructure of dentine.

Methods: Each extracted molars was made into four identical dentinal specimens, which were randomly divided into 4 groups according to the treatment methods: A, control group; B, pulsed CO2 laser irradiation; C, coated with 38%Ag(NH3)2F; and D, laser irradiation plus fluoride. Scanning electron microscope (SEM) analysis was performed.

[Mutation and expression of tumor suppressor gene phosphatase and tensin homolog deleted in chromosome 10 in oral squamous cell carcinoma].

Objective: To investigate the role of mutation and mRNA expression of tumor suppressor gene phosphatase and tensin homolog deleted in chromosome 10 (PTEN) in tumorigenesis and progression of oral squamous cell carcinoma (OSCC).

Methods: The mutation of exon 3, 5, 6 and exon 8 of PTEN gene in 42 oral squamous cell carcinoma tissue and paired normal tissue were detected by polymerase chain reaction (PCR) and DNA sequencing methods. The levels of PTEN mRNA expression in these tissues were assayed using semi-quantitative RT-PCR.

[Reconstruction of large through-and-through palate defects with folded free forearm flap].

Objective: To explore the reconstruction method of large through-and-through palate defects.

Methods: From 2003 to 2006, 7 cases of large through-and-through palate defects were reconstructed with vascularized folded free forearm flap. 8 flaps were used, including 7 free forearm flaps and 1 pectoralis major myocutaneous flap.

[Evaluation of midazolam intravenous sedated patient's comfort degree in mandibular third molar surgery].

Objective: To evaluate the clinical efficacy and safety of continuous low-flow intravenous infusion of midazolam sedation in mandibular third molar surgery.

Methods: Fifty healthy patients with symmetrically placed impacted bilateral mandibular third molars were included in this self controlled, randomized clinical study. Degree of comfort (their actual current anxiety level) was assessed using a visual analogue scale (VAS) of pain and anxiety.

[Continuous intravenous infusion of midazolam: a clinical study of conscious sedation for dental phobia].

Objective: To evaluate the sedative effect of continuous intravenous infusion of midazolam in treating severe dental phobia.

Methods: 31 patients with severe dental phobia were enrolled and all of them had good communication with dentists. Two teeth in each patient were assigned to control group and experiment group seperately.