The comparison of clinical and biological characteristics between IDH1 and IDH2 mutations in gliomas.

Background: Mutations in isocitrate dehydrogenase 1 (IDH1) and isocitrate dehydrogenase 2 (IDH2) are frequent in low-grade gliomas and secondary glioblastomas (sGBM). Because they yield the same oncometabolite, D-2-hydroxyglutarate, they are often treated as equivalent and pooled. The objective of this study was to provide insight into the differences between IDH1 and IDH2 mutant gliomas.

Responses of benthic foraminifera to the 2011 oil spill in the Bohai Sea, PR China.

The 2011 oil spill in the Bohai Sea was the largest spill event in China. Nine sediment cores were taken near the spill site and environmental factors including Polycyclic Aromatic Hydrocarbon (PAHs), oils, sulfides, organic carbon were measured 6 months later. Benthic foraminifera were separated into >150 μm (large) and 63-150 μm (small) size fractions for 2-cm depth interval of each sediment core.

Use of acellular dermal matrix combined with a component separation technique for repair of contaminated large ventral hernias: a possible ideal solution for this clinical challenge.

Repair of large contaminated ventral hernias is always challenging because of massive loss of muscular and fascial tissues, high risk of surgical infection and recurrence, and contraindication to use of a permanent prosthesis. This study reviewed retrospectively data of 35 patients with contaminated large ventral hernias who received repair using acellular dermal matrix combined with a component separation technique from 2009 to 2011. Twenty-one males and 14 females were identified with a mean age of 45.

[Effect of elemene on reversing chemoresistance to adriamycin in human stomach cancer cell line].

Objective: To investigate the effect of elemene on reversing chemoresistance to adriamycin (ADM) in human stomach cancer cell, and explore its possible mechanism.

Methods: SGC7901/ADM were divided imto two groups: control group and elemene treatment group. The cytotoxicity of ADM on SGC7901/ADM was determined by MTT assay.

Significance of measurements of herniary area and volume and abdominal cavity volume in the treatment of incisional hernia: application of CT 3D reconstruction in 17 cases.

Objective: To investigate the value of CT 3D reconstruction in the diagnosis and treatment of incisional hernia and the related factor of abdominal cavity volume.

Methods: Abdominal wall defect and herniary volume were measured using 3D reconstruction based on plain CT scans in 17 patients with incisional hernias.

Results: The herniary diameter, area and volume could be measured in the 17 patients and the abdominal cavity volume was also measured in 10 patients using the 3D reconstruction technique.

Treatment for incisional parapubic hernia: an experience of 25 cases.

We retrospectively studied the clinical manifestation, diagnosis, treatment, and therapeutic effect in 25 cases of incisional parapubic hernia. We believe that it is necessary for patients with recurrent hernia to undergo CT detection; the mesh patch should be adequately large, and must be doubly fixed before and after the pubic bone. Sublay and intraperitoneal onlay mesh technique both can obtain good therapeutic effects for incisional parapubic hernia.

Image Analysis of Breast Tumors Using Thermal Texture Mapping (TTM).

To explore the characteristics of thermo-source of breast tumors on Thermal Texture Maps. Compared with the histological results, thermo-source characteristics on TTM in 106 cases with breast mass, who would undergo breast surgery, were analyzed according to the parameters such as the depth, morphology, structure, and temperatures of abnormal heat foci in order to find the differences between benign diseases and malignant tumors. The coincidence rates of Thermal Texture Maps with pathological findings and the corresponding thermo-eradiate values in 49 cases with malignancy and 57 cases with benign diseases were 89.

[Clinical study on bacterial translocation in severe multiple trauma patients].

Objective: To investigate bacterial translocation in severe multiple trauma patients using polymerase chain reaction (PCR) to detect the presence of bacteria in the blood.

Methods: Sixteen severe multiple trauma patients [injury severity score (ISS)>20] in surgery intensive care unit (SICU) were selected. Blood samples were collected 2, 24 and 48 hours after trauma for bacterial culture and microbial DNA detection.

[Effects of anticoagulation therapy with low molecular weight heparin in acute pancreatitis].

Objective: To evaluate the effects of anticoagulation therapy with low molecular weight heparin in acute pancreatitis.

Methods: Low molecular weight heparin, in a dose of 40 mg or 0.01 ml/kg, by subcutaneous injection, every 12 hours, was administered to 17 acute pancreatitis patients combined with conventional therapy.

[Expression of a novel human interleukin-13 in E.coli and its biological activity assay].

Aim: To express a novel Gln98-deleted human interleukin-13 in E.coli.

Methods: Total RNA was isolated from Jurkat cells costimulated with PHA and ConA.