Publications by authors named "Ji-xun Zhan"
[Progress in biotransformation of triptolides and bufadienolides].
Beijing Da Xue Xue Bao Yi Xue Ban
February 2004
Article Synopsis
- The research group summarized their latest findings on how triptolides and bufadienolides undergo biotransformation.
- They explored the current methodologies and results related to these compounds.
- The discussion included potential future directions for research in biotransformation processes.
Aim: To study the microbial transformation of sinenxan A.
Methods: Choose two strains of Fungi (Mucor spinosus AS 3.3450 and Cunninghamella echinulata AS 3.
Artemisinin (1) was transformed by Mucor polymorphosporus and Aspergillus niger. Five products were identified as 9beta-hydroxyartemisinin (2), 3beta-hydroxyartemisinin (3), deoxyartemisinin (4), 3beta-hydroxydeoxyartemisinin (5), and 1alpha-hydroxydeoxyartemisinin (6). Products 2, 3, and 6 are new compounds.
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