SoySNP618K array: A high-resolution single nucleotide polymorphism platform as a valuable genomic resource for soybean genetics and breeding.

Innovations in genomics have enabled the development of low-cost, high-resolution, single nucleotide polymorphism (SNP) genotyping arrays that accelerate breeding progress and support basic research in crop science. Here, we developed and validated the SoySNP618K array (618,888 SNPs) for the important crop soybean. The SNPs were selected from whole-genome resequencing data containing 2,214 diverse soybean accessions; 29.

miR‑195 promotes LPS‑mediated intestinal epithelial cell apoptosis via targeting SIRT1/eIF2a.

A microarray analysis of an animal model with experimental sepsis induced by caecal ligation and puncture revealed that the level of microRNA‑195 (miR‑195) was upregulated. However, to the best of our knowledge, the role of miR‑195 in sepsis remains unknown. The present study investigated the effect of miR‑195 on apoptosis in sepsis and investigated the underlying mechanism.

AMPK alleviates endoplasmic reticulum stress by inducing the ER-chaperone ORP150 via FOXO1 to protect human bronchial cells from apoptosis.

Chronic obstructive pulmonary disease (COPD), is characterized by inflammation of airways accompanied by a progressive destruction of lung parenchyma. This process is initiated in most cases by cigarette smoking. In this study we investigated the role of AMP activated protein kinase (AMPK) in cigarette smoke extract (CSE)-induced airway epithelial cell apoptosis as a consequence of endoplasmic reticulum stress (ER stress).

[Discriminate the Rape Sclerotinia at Early Stage Based on Confocal Raman Spectroscopy].

Oilseed rape(Brassica napus L. ) is a principal source of edible oil for human consumption and it feeds livestock as a by product with high energy and protein. However, oilseed plants often suffer from the invasion of various diseases, which could affect the yield and quality of the rapeseeds.

The synthesis of 4,7-disubstituted-2H-benzo[b][1,4]-oxazin-3(4H)-ones using Smiles rearrangement and their in vitro evaluation as platelet aggregation inhibitors.

A series of novel benzo[b][1,4]oxazin-3(4H)-one derivatives were synthesized as platelet aggregation inhibitors for structure-activity relationships (SAR) analysis. The synthetic pattern, involved Smiles rearrangement for the preparation of benzoxazine, was proven to be more efficient than the conventional methods. Biological evaluation demonstrated that among all the synthesized compounds, compound 9u (IC50=9.

UV spectroscopic studies and charge transfer properties of azobenzene-containing cyclopentadienyliron complexes of arenes: a combined experimental and density functional theoretical study.

This study investigates the UV-Vis absorption and fluorescence emission of newly synthesized (η(6)-4-(4-nitrophenylazo) phenoxyl benzene) (η(5)-cyclopentadienyl) iron hexafluorophosphate (Fc-azo). Quantum chemical calculations of the orbital energy, geometrical structure, absorption spectra, and first hyperpolarizability (β) values of the Fc-azo were carried out using density functional (DFT/B3LYP and TD-DFT) methods. Comparisons between hydroxyl azobenzene compound and Fc-azo were made.

[Effects of exogenous tetracycline on rape soil enzyme activity and rape quality].

This paper studied the effects of applying different concentration (0, 0.30, 0.60, and 0.

Clinical observation on treatment of depression by electro-acupuncture combined with Paroxetine.

Objective: To observe the clinical efficacy and adverse reactions of Paroxetine combined with electro-acupuncture (EA) in treating depression.

Methods: Forty-two patients with depression were randomly assigned to the observation group (22 patients) treated with EA combined with Paroxetine, and the control group (20 patients) treated with Paroxetine alone, and the therapeutic course for both groups was 6 weeks. The therapeutic efficacy and adverse reactions were evaluated with scores by Hamilton depression scale (HAMD) and treatment emergent symptoms scale (TESS), respectively.