Publications by authors named "Ji-hui Yue"
Article Synopsis
- The study investigates the alterations in functional homotopy architecture in patients with Major Depressive Disorder (MDD), highlighting a significant reduction in functional connectivity between homotopic brain regions.
- Using resting-state fMRI data from over 1,000 MDD patients and nearly 900 healthy controls, researchers found specific areas in the brain, like the posterior cingulate gyrus and precuneus, showed notably decreased connectivity in MDDs, with variations related to age and gender.
- The findings suggest that structural connectivity deficits in MDD may impact how information is exchanged between the brain's hemispheres, correlating with the severity of depressive symptoms and indicating potential areas for further study in treatment.
Previous research characterizes obsessive compulsive disorder (OCD) as a complex neurobehavioral disorder that may have multiple etiologies ( den Braber et al., 2008 ). This study analyzed neurocognitive function and change in regional cerebral blood flow (rCBF) to characterize OCD.
View Article and Find Full Text PDFObjective: To analyze the correlation between the pharmacotherapy response and the characteristics of the pre-treatment regional cerebral blood flow (rCBF) in patients with obsessive-compulsive disorder (OCD).
Methods: Single-photon emission-computed tomography (SPECT) was used to determine the pre-treatment rCBF in 30 OCD patients and 30 normal controls. Based on their clinical remission response, the subjects were divided into two groups: selective serotonin reuptake inhibitors (SSRIs) and SSRIs plus quetiapine.
Objective: To explore the change characteristics of regional cerebral blood flow (rCBF) and its correlation with curative efficacy in patients with obsessive-compulsive disorder (OCD).
Methods: The images of rCBF and computed tomography (CT) were acquired from 30 OCD and 30 normal controls by single photon emission computed tomography (SPECT) and CT. The tomographic data of rCBF were normalized, smoothed and statistically processed with the statistical parametric mapping (SPM) software with two-sample Z-test.