Publications by authors named "Ji-Zhang Shen"

Background: The few studies on MR colonography with air enema involved feasibility of bowel distention and imaging quality and lacked detection sensitivity of colorectal neoplasms. The purpose of this prospective study was to assess the detection sensitivity of colorectal neoplasms with the three-dimensional Fourier transform fast spoiled gradient-recalled MR colonography with air enema.

Methods: A total of 30 patients scheduled for optical colonoscopy due to rectal bleeding, positive fecal occult blood test results or altered bowel habits were recruited and successfully underwent entire colorectal examinations with three-dimensional Fourier transform fast spoiled gradient-recalled MR colonography and subsequent optical colonoscopy on the same day.

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Article Synopsis
  • The study evaluated the effects of sublingual nitroglycerin (NTG) on coronary MR angiography (MRA) in 15 volunteers, focusing on timing, artery diameter, and image quality.
  • Post-NTG results showed a significant increase in lumen diameter (average 25.35% increase) and improvements in trigger delay and acquisition window, while scanning time increased.
  • Despite improvements, NTG administration also had some drawbacks, including less effective vasodilation in the left circumflex artery and decreased image quality in certain segments, suggesting the need for further research on mitigating these issues.
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Objective: To evaluate the clinical practical value of apparent diffusion coefficient (ADC) measurements based on diffusion-weighted MR imaging (DWI) for quantification of liver fibrosis and inflammation for hepatitis viral infection.

Methods: Diffusion-weighted MRI with parallel imaging was prospectively performed on 85 patients with chronic hepatitis and on 22 healthy volunteers within a single breath-hold using a single-shot spin-echo echo-planar sequence at b values of 100, 300, 500, 800 and 1000 s/mm2 respectively. ADC values of liver were measured with five different b values.

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Objective: To evaluate the added value of single breath-hold diffusion-weighted imaging (DWI) in detection of small HCC lesions (
Methods: A total of 54 patients with chronic liver diseases underwent abdominal MRI at 1.5 T, including T1-weighted (T1WI), T2-weighted (T2WI), and 2D conventional DCE.

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Article Synopsis
  • The study evaluated parallel-imaging techniques in free-breathing whole-heart 3D coronary magnetic resonance angiography (MRA) and assessed navigator strategies for visualizing major coronary arteries.
  • GRAPPA imaging showed advantages, including higher signal-to-noise and contrast-to-noise ratios, as well as fewer artifacts compared to mSENSE images.
  • Among the navigator techniques, 2D-PACE outperformed 1D-PACE in terms of efficiency, scan time, and image quality, suggesting that the combination of whole-heart 3D coronary MRA and advanced parallel-imaging is a promising clinical approach.
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Objective: To prospectively analyze the correlation of MRI image characteristics with histopathological findings in pancreatic head carcinoma in vivo and ex vivo.

Methods: Sixteen patients with pancreatic head carcinoma were examined by 1.5T MRI.

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Aim: To evaluate the efficacy of ferucarbotran-enhanced MR imaging in the detection of focal hepatic lesions compared to plain and Gd-DTPA-enhanced MR imaging.

Methods: Fifty-nine patients with suspected focal hepatic lesions were admitted to the study. Plain MR imaging (FSE T(2)WI with fat suppression and GRE T(1)WI sequences) and Gd-DTPA dynamic enhanced MR of the liver were initially performed followed by ferucarbotran-enhanced MR imaging 48 h later (including GRE T(1)WI, FSE T(2)WI with fat suppression, and GRE T(2)WI sequences).

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Objectives: To analyze the MRI manifestations and pathological changes of hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE) with lipiodol.

Methods: 23 patients with 31 HCC lesions treated by TACE underwent MRI examination within 1 week before their surgical resections. MRI was performed with SE sequence (T1WI and FSE T2WI) and FMPSPGR sequence dynamic multi-phase contrast scans.

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Objectives: To study prospectively the enhancement features of small hepatocellular carcinoma (SHCC) with multi-phase scanning of dynamic MRI and spiral CT, and discuss the superiority of dynamic MRI to spiral CT.

Methods: Multi-phase dynamic contrast scanning of high field MRI and spiral CT were performed in 53 patients with SHCC. The arterial phase, portal venous phase and delayed phase scanning of spiral CT was done after the pre-contrast scanning of the entire liver.

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Aim: To evaluate the value of superparamagnetic iron oxide (SPIO) enhanced MRI in characterizing focal hepatic lesions.

Methods: Forty-three patients (32 men,11 women, mean age 51 years, age range 25-74 years) with previously identified focal hepatic lesions were enrolled into this study. All the patients underwent plain, Gd-DTPA enhanced MRI and the SPIO enhanced MRI 1-7 d later.

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