Reliable performance of composite adhesive joints under low-velocity impact is essential for ensuring the structural durability of composite materials in demanding applications. To address this, the study examines the effects of temperature, surface treatment techniques, and bonding processes on interlaminar fracture toughness, aiming to identify optimal conditions that enhance impact resistance. A Taguchi experimental design and analysis of variance (ANOVA) were used to analyze these factors, and experimentally derived toughness values were applied to low-velocity impact simulations to assess delamination behavior.
View Article and Find Full Text PDFis a rare shrub which grows in Korea and China. Pericarp of has been used as a crude medicine, but there are few researches about the pharmacologic activities. The present study was designed to investigate the anti-allergic inflammatory activities of the essential oil from fruits of ().
View Article and Find Full Text PDFJ Assoc Res Otolaryngol
April 2014
Metformin, an antidiabetic drug with potent anticancer activity, is known to prevent oxidative stress-induced cell death in several cell types through a mechanism dependent on the mitochondria. In the present study, we investigated the influence of metformin on cisplatin ototoxicity in an auditory cell line. Cell viability was determined using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide (Sigma, St.
View Article and Find Full Text PDFBesides their prominent function in cellular energy metabolism, the central role of mitochondria has been focused on control of cellular death in last decades. The mitochondrial permeability transition pore (PTP) is involved in the intrinsic pathway of apoptosis via the release of cytochrome c into cytosol. Metformin, a drug widely used in the treatment of type II diabetes, has recently received attention owing to new findings regarding its effect on apoptosis through mitochondrial permeability transition and cytochrome c release.
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