Publications by authors named "Ji-Yoon Guk"
Haplotype-level allelic characterization facilitates research on the functional, evolutionary and breeding-related features of extremely large and complex plant genomes. We report a 21.7-Gb chromosome-level haplotype-resolved assembly in Pinus densiflora.
View Article and Find Full Text PDFBackground: The plant homeodomain (PHD)-finger gene family that belongs to zinc-finger genes, plays an important role in epigenetics by regulating gene expression in eukaryotes. However, inaccurate annotation of PHD-finger genes hinders further downstream comparative, evolutionary, and functional studies.
Results: We performed genome-wide re-annotation in Arabidopsis thaliana (Arabidopsis), Oryza sativa (rice), Capsicum annuum (pepper), Solanum tuberosum (potato), and Solanum lycopersicum (tomato) to better understand the role of PHD-finger genes in these species.
Article Synopsis
- - Genome phasing is a new method that creates detailed genetic assemblies by distinguishing between different versions of genes (haplotypes), which traditional methods often ignore, leading to mixed genomic results.
- - This review examines popular phasing tools like TrioCanu, FALCON-Phase, and ALLHiC and highlights the significant genetic differences revealed by haplotype-resolved assemblies, which can affect plant characteristics such as gene expression and chromosomal arrangements.
- - The authors also discuss the current limitations of genome phasing techniques and propose future research directions to enhance their effectiveness, making it easier for scientists to study complex plant genomes.