Chronic wasting disease (CWD) is a deleterious brain proteinopathy caused by a pathogenic form of prion protein (PrP), which is converted from a benign form of prion protein (PrP) encoded by the prion protein gene (). In elk, the M132L single nucleotide polymorphism (SNP) of the gene likely plays a pivotal role in susceptibility to CWD. However, the association of the M132L SNP with susceptibility to CWD has not been evaluated in Korean elk to date.
View Article and Find Full Text PDFPrion diseases are transmissible spongiform encephalopathies caused by deleterious prion protein (PrP ) derived from normal prion protein (PrP ), which is encoded by the prion protein gene (PRNP). We performed an in-depth examination to detect PrP by using enzyme immunoassay (EIA), real-time quaking-induced conversion reactions (RT-QuIC) and protein misfolding cyclic amplification (PMCA) in nine brain tissues derived from three Holstein cattle carrying the E211K somatic mutation of the bovine PRNP gene. The EIA, RT-QuIC and PMCA analyses were not able to detect the PrP band in any tested samples.
View Article and Find Full Text PDFOrganic material-based solar cell devices such as perovskite solar cells (PSCs) have attracted attention as renewable energy resources with low production cost, lightweight, wearable device applications, and large-area processability. To enhance device performance, many research groups have attempted to develop new materials and structures. Metal electrode materials play an important role in solar energy conversion in PSCs, owing to the ohmic contact and contact resistance between metal negative electrodes and photoactive layers.
View Article and Find Full Text PDFThe perovskite solar cell is capable of energy conversion in a wide range of wavelengths, from 300 nm to 800 nm, which includes the entire visible region and portions of the ultraviolet and infrared regions. To increase light transmittance of perovskite solar cells and reduce manufacturing cost of perovskite solar cells, soda-lime glass and transparent conducting oxides, such as indium tin oxide and fluorine-doped tin oxide are mainly used as substrates and light-transmitting electrodes, respectively. However, it is evident from the transmittance of soda-lime glass and transparent conductive oxides measured via UV-Vis spectrometry that they absorb all light near and below 310 nm.
View Article and Find Full Text PDF(Erxleben, 1777) has been used as a model species of Chronic Wasting Disease (CWD). We completed the mitochondrial genome of , susceptible to the CWD. Its length is 16,428 bp, identical to the previous mitochondrial genome of , and 37 genes (13 protein-coding genes, two rRNAs, and 22 tRNAs) were identified.
View Article and Find Full Text PDF(Merriam, 1905) is one of the subspecies of elk distributed only in California, USA. We completed the first mitogenome of . Its length is 16,428 bp, which is in middle among 24 available mitogenomes.
View Article and Find Full Text PDFBackground/aim: Antimicrobial resistance significantly affects the cure rate of Helicobacter pylori (H. pylori) eradication. We evaluated the risk factor of failure in ultimate H.
View Article and Find Full Text PDFThe power conversion efficiency of perovskite solar cells, which are next-generation photovoltaic cells, has rapidly increased up to 20% through ongoing research and development. Recently, various methods have been employed to increase the active area of the mesoporous layer in perovskite solar cells. In this study, the particle aggregation of the TiO₂ was controlled by adding Ti-diisopropoxide bis to the mesoporous layer solution; thus, the contact area between the mesoporous layer and perovskite layer was increased.
View Article and Find Full Text PDFAfrican swine fever, a fatal haemorrhagic disease of swine, was confirmed in domestic pigs for the first time in South Korea in September 2019. The causative virus belonged to the p72 genotype II and had an additional tandem repeat sequence in the intergenic region (IGR) between the I73R and I329L.
View Article and Find Full Text PDFwas isolated from 25 (11.1%) of 225 sampled horses and from 16 (35.56%) of 45 farms.
View Article and Find Full Text PDFThe number and distribution of Eurasian otters have declined during twentieth century due to human activity and water pollution. The global conservation status of Eurasian otter is presently 'Near Threatened (NT)' and strictly protected by being listed on the international legislation and conventions. A number of studies using the mitochondrial DNA (mtDNA) control region (CR) have been conducted in order to effectively apply conservation and reintroduction programs, especially in Europe.
View Article and Find Full Text PDFLiquid-based cytology (LBC) is being increasingly used for body fluid specimens and has improved diagnostic accuracy when compared to conventional smears. We compared the diagnostic accuracy and cellular morphologic features between CellprepPlus® LBC and ThinPrep® LBC in effusion cytology. One hundred and eighty body fluid specimens, consisting of 119 pleural fluid specimens, 59 peritoneal fluid specimens, and 2 pericardial fluid specimens, were obtained from 166 patients.
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