Publications by authors named "Ji-Yang Jin"
Background: The extracellular volume fraction (ECV) derived from cardiac magnetic resonance imaging (MRI) is extensively used to evaluate myocardial fibrosis. However, due to the limited histological verification in healthy individuals, it remains unclear whether the size of cardiomyocytes may play a potential role in the physiological changes of ECV. The aim of this study was to examine the association between cardiomyocyte size and myocardial ECV by using a healthy porcine model.
View Article and Find Full Text PDFObjectives: To determine the performance of chemical shift signal intensity index (CS-SII) values for distinguishing minimal-fat renal angiomyolipoma (mfAML) from renal cell carcinoma (RCC) and to assess RCC subtype characterisation.
Methods: We identified eligible studies on CS magnetic resonance imaging (CS-MRI) of focal renal lesions via PubMed, Embase, and the Cochrane Library. CS-SII values were extracted by lesion type and evaluated using linear mixed model-based meta-regression.
Article Synopsis
- Platelet-rich plasma (PRP) shows potential for treating intervertebral disc degeneration (IDD), but its short-lived growth factors limit continuous stimulation of damaged discs.
- This study analyzed the combined use of PRP and bone marrow-derived mesenchymal stem cells (BMSCs) in rabbits with induced early IDD, demonstrating enhanced disc repair compared to PRP alone or a control group.
- Results at 8 weeks post-treatment indicated significant restoration of the degenerated discs in the PRP-BMSC group, suggesting a more effective therapeutic strategy for early IDD recovery.
Article Synopsis
- The article investigates how different injection sites (head, arm, leg) affect image quality and radiation exposure in pediatric cardiovascular CT angiography using 64-MDCT technology.
- The study involved 61 children, measuring various metrics like signal-to-noise ratio and effective dose across three different groups based on injection site.
- Results showed no significant differences in overall image quality but noted slight variations in aorta image quality and significant differences in radiation dose, suggesting the need for optimizing prescanning protocols to minimize exposure.
[Diagnostic value of 64 multislice CT in typing of congenital aortic anomaly in neonates and infants].
Zhonghua Yi Xue Za Zhi
August 2010
Article Synopsis
- - The study evaluates the effectiveness of 64-slice multislice CT (MSCT) in diagnosing congenital aortic anomalies in infants, finding it to be highly accurate with diagnostic sensitivity, specificity, and accuracy all at 100%.
- - A total of 120 pediatric patients with congenital heart disease underwent MSCT, revealing 36 congenital aortic anomalies, which included various types such as coarctation of the aorta and different aortic arch configurations.
- - The findings suggest that while MSCT provides detailed anatomical assessments necessary for surgical planning, using 80 kV for CT scans in infants under one year old is recommended to minimize radiation exposure.
Article Synopsis
- The study investigates whether mesenchymal stem cells (MSCs) labeled with magnetic nanoparticles can become liver cells (hepatocytes) when injected into mice with liver damage from carbon tetrachloride (CCl4).
- Researchers created a mouse model to track these MSCs using magnetic resonance imaging (MRI) and found that the labeled cells migrated to the liver, although they showed limited liver function improvement.
- Histological analysis confirmed liver damage and fibrosis in the MSC-injected groups, with a high correlation between labeled MSCs and the presence of liver-specific proteins, indicating some transdifferentiation into functional liver cells.
Article Synopsis
- The Mint protein family consists of three members: Mint1, Mint2, and Mint3, with Mint1 and Mint2 specifically expressed in neurons, while Mint3 is found everywhere.
- Research on rat spinal cord revealed that Mint2 protein levels are higher than Mint1, with Mint2 mRNA widely distributed throughout different spinal cord sections and concentrated in motor neurons.
- Mint2 was localized mainly in the perikaryon and vesicles of motor neurons and showed presence in axons and presynaptic terminals, indicating its potentially significant role in spinal cord functions compared to Mint1.