Publications by authors named "Ji-Xun Lin"
Front Immunol
December 2023
Article Synopsis
- The paper examines the effectiveness of using chemotherapy along with CD19 and CD20 monoclonal antibodies to treat minimal residual disease (MRD) in children with refractory acute B-lymphoblastic leukemia (B-ALL) and discusses relevant research.
- A 4-year-old boy with B-ALL was treated according to the SCCLG-ALL-2016 protocol but initially had persistent MRD until he was given a combination of consolidation chemotherapy and monoclonal antibodies, leading to a negative MRD result and successful stem cell transplantation.
- The study concludes that this treatment approach significantly improves remission rates in refractory B-ALL, showing no adverse effects and suggesting its potential as a viable treatment option for these patients.
