Using intravoxel incoherent motion imaging to evaluate uric acid-induced renal injury and efficacy after treatment.

Objectives: To validate the feasibility of intravoxel incoherent motion imaging (IVIM) for monitoring renal injury and uric acid-lowering efficacy in a rat model of hyperuricaemia.

Methods: A total of 92 rats were analysed and categorized into 4 groups: control (CON), hyperuricaemia (HUA), allopurinol intervention (ALL), and combined intervention (COM). Eight rats were randomly selected from each group and underwent IVIM scanning on days 0, 1, 3, 5, 7, and 9.

Finite Beam Element for Curved Steel-Concrete Composite Box Beams Considering Time-Dependent Effect.

Curved steel-concrete composite box beams are widely used in urban overpasses and ramp bridges. In contrast to straight composite beams, curved composite box beams exhibit complex mechanical behavior with bending-torsion coupling, including constrained torsion, distortion, and interfacial biaxial slip. The shear-lag effect and curvature variation in the radial direction should be taken into account when the beam is sufficiently wide.