Publications by authors named "Ji-Xiang Jia"
Article Synopsis
- Congenital disorders of glycosylation (CDGs) are complex genetic diseases linked to issues in glycan production, making diagnosis difficult due to their varied symptoms.
- Recent research focused on developing a liposome-based vaccine that includes specific biomarkers for ALG1-CDG and PMM2-CDG, enhancing immune responses and promoting the production of high-affinity IgG antibodies.
- The study found that the new vaccine platform effectively generated strong IgG responses targeted at CDG biomarkers, indicating potential for rapid diagnostic methods for these disorders.
Congenital disorders of glycosylation (CDG) are a growing group diseases that result from defects in genes involved in glycan biosynthesis pathways. One tetrasaccharide, i.e.
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