Use of Evidence-Based Research Approach in RCTs of Acupuncture-Related Therapies for Primary Dysmenorrhea: A Meta-Research.

Objective: To assess the use of evidence-based research (EBR) approach in randomized controlled trials (RCTs) of acupuncture-related therapies for primary dysmenorrhea (PD).

Methods: PubMed, EMBASE, Cochrane Library, China National Knowledge Infrastructure, Wanfang Database, Chinese Biomedical Database, and China Science and Technology Journal Database were searched from January 2013 to December 2022 for RCTs of acupuncture on PD. The full text and references of each RCT were read to assess whether systematic reviews (SRs) or other types of studies with similar research questions and end-users' perspectives were cited to justify and design the trial.

Factors Associated with the Magnitude Of acUpuncture treatment effectS (FAMOUS): a meta-epidemiological study of acupuncture randomised controlled trials.

Objective: To identify factors and assess to what extent they impact the magnitude of the treatment effect of acupuncture therapies across therapeutic areas.

Data Source: Medline, Embase, Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure, Wanfang Database, VIP Database, and China Biology Medicine disc, between 2015 and 2019.

Study Selection: The inclusion criteria were trials with a total number of randomised patients larger than 100, at least one patient-important outcome and one of two sets of comparisons.

[Overview of systematic reviews of acupuncture clinical research published in international journals].

The systematic reviews (SRs) of acupuncture published before December 31 of 2020 in PubMed, Cochrane and EMbase databases were searched, and the publication overview of international acupuncture SRs were analyzed. As a result, a total of 717 SRs were included, and the overall number of published SRs showed a fluctuating upward trend. A total of 15 categories of diseases were involved, of which 113 SRs suggested that acupuncture was effective, and 12 SRs did not support acupuncture, and the remaining SRs showed uncertain conclusions.

Corrigendum: Exercising With a Six Pack in Virtual Reality: Examining the Proteus Effect of Avatar Body Shape and Sex on Self-Efficacy for Core-Muscle Exercise, Self-Concept of Body Shape, and Actual Physical Activity.

[This corrects the article DOI: 10.3389/fpsyg.2021.

[Clinical study on acupuncture and moxibustion for frozen shoulder: an evidence map].

The clinical evidences on acupuncture and moxibustion for the treatment of frozen shoulder were sorted and summarized systematically. The relevant articles of frozen shoulder treated with acupuncture and moxibustion were searched from PubMed, EMbase, Cochrane database of systematic review (CDSR), Cochrane database of controlled trials register (CENTRAL), China national knowledge infrastructure (CNKI), Wanfang, VIP, and Chinese biomedical literature databases (SinoMed), from database inception to May 31, 2021. Using AMSTAR-2, the methodological quality of the included systematic reviews was evaluated.

Effect of Acupuncture on Outcomes of in vitro Fertilisation: A Scoping Review.

Objectives: To identify, examine and summarize the available evidence on the effectiveness and safety of acupuncture for in vitro fertilisation (IVF) outcomes.

Methods: Eight electronic databases, including PubMed, EMBASE, Cochrane Database of Systematic Review, Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure, Wanfang Database, Chinese Biomedical Database and VIP Database, were searched, supplemented by manual searches. Two researchers independently conducted the literature screening, data extraction, and methodological quality assessments.

BRAF V600E mutation is associated with aggressive features in papillary thyroid carcinomas ≤ 1.5 cm.

Background: While some studies suggest that the BRAF V600E mutation correlates with a high-risk phenotype in papillary thyroid microcarcinoma (PTMC), more evidence is necessary before this mutation can be used to help guide decision making in the management of small thyroid nodules. This study investigated whether BRAF V600E mutation is associated with aggressive features in PTMC (≤ 1 cm) and small PTC (1-1.5 cm).

Exercising With a Six Pack in Virtual Reality: Examining the Proteus Effect of Avatar Body Shape and Sex on Self-Efficacy for Core-Muscle Exercise, Self-Concept of Body Shape, and Actual Physical Activity.

This study investigates the Proteus effect from the first-person perspective and during avatar embodiment in actual exercise. In addition to the immediate measurements of the Proteus effect, prolonged effects such as next-day perception and exercise-related outcomes are also explored. We theorized the Proteus effect as altered perceived self-concept and explored the association between virtual reality (VR) avatar manipulation and self-concept in the exercise context.

[Release Risk of Phosphorus by Sediments and Its Influencing Factors in Ponds and Ditches of a New Urban District Park].

This study examined five ponds and three ditches in the Shufengwan Sports Park in a new urban district of Hefei City, from which surface-layer sediments and overlying water samples were collected during autumn, winter, and summer. The equilibrium phosphate concentrations (EPC) of the sediments and its response to exogenous carbon or nitrogen were then measured. The resulting EPCvalues were used to assess the risk of phosphorus release by the sediments.

[Effect of manual acupuncture of "Shuigou" (GV26)"Neiguan" (PC6) on neurological function and expression of apoptosis-related factors in brain tissues surrounding hematoma in intracerebral hemorrhage rats].

Objective: To observe the effect of manual acupuncture stimulation of "Shuigou" (GV26) and "Neiguan" (PC6) on neurological function and expression of Caspase-3 and Caspase-9 in brain tissues around the intracerebral hematoma in rats with acute intracerebral hemorrhage (ICH), so as to explore its possible mechanisms underlying improvement of ICH.

Methods: Ninety-six male SD rats were randomly divided into 4 groups: control, model, acupoint and non-acupoint (24 rats in each group). The ICH model was established by injection of the rat's autologous blood into the caudate nucleus.

Glucocorticoid resistance syndrome caused by a novel NR3C1 point mutation.

Glucocorticoid resistance syndrome (GRS) is a rare genetic disorder caused by inactivating mutations of the NR3C1 gene which encodes the glucocorticoid receptor. The phenotypic spectrum is broad but typically include symptoms of adrenal insufficiency, mineralocorticoid excess and hyperandrogenism. We report a new case associated with a novel NR3C1 mutation.

Lugol's solution-induced painless thyroiditis.

Unlabelled: Lugol's solution is usually employed for a limited period for thyroidectomy preparation in patients with Graves' disease and for the control of severe thyrotoxicosis and thyroid storm. We describe a rare case of Lugol's solution-induced painless thyroiditis. In November 2014, a 59-year-old woman was prescribed Lugol's solution four drops per day for the alleviation of menopausal symptoms.

Hereditary Heterozygous C2 Deficiency: Variable Clinical and Serological Manifestations Among Three Sisters.

The causal link between inherited complement deficiencies and systemic lupus erythematosus (SLE) has been well established, although it remains a rare cause of the disease. We present the case of three biological sisters with hereditary heterozygous C2 deficiency, but who differ widely in their clinical and serological manifestations. Patient 1 is 25 years old and was diagnosed with SLE at the age of 12.

Are There Benefits for Gestational Diabetes Mellitus in Treating Lower Levels of Hyperglycemia Than Standard Recommendations?

Objectives: The new International Association of Diabetes and Pregnancy Study Groups (IADPSG) recommendations for diagnosis of gestational diabetes mellitus (GDM) are generating discussion regarding their universal adoption. Our centre is currently using stricter GDM diagnostic criteria than those proposed by the IADPSG. Evaluation of complication rates and their predictors in our cohort may provide insight for the care of this high-risk population.

Quantification of the External Validity of Randomized Controlled Trials Supporting Clinical Care Guidelines: The Case of Thromboprophylaxis.

Background: Clinical guidelines are based on the results of several randomized controlled trials. However, due to the stringent exclusion criteria of these trials, their external validity may be low. We aimed to evaluate the external validity of the randomized controlled trials cited in the American College of Chest Physicians guidelines for the use of pharmacological thromboprophylaxis in hospitalized medical patients.

[Influence of transient storage on solute transport and the parameter sensitivity analysis in a suburban drainage ditch].

From September to October 2013, five in-stream tracer experiments involving slug additions of chloride were performed in Guanzhenhe Branch, a headwater stream in suburban Hefei. From the perspective of different transport mechanisms such as transient storage, lateral inflow and advection-dispersion, four scenarios were set to analyze the effects of transient storage on solute transport in the drainage ditch. And sensitivity analysis of parameters in OTIS model was conducted.

[Characteristics of nitrogen and phosphorus retention in two different channel forms in a typical headwater stream in the suburb of Hefei City, China ].

To investigate the characteristics of ammonium and phosphorus retention in two typical channel forms, deep pool and winding ditch in headwater stream, four field tracer experiments were conducted in a first-order stream of Ershibu River in Hefei suburban, in which a solution of biologically active (NH4Cl and KH2PO4) and conservative (NaCl) tracers was released to the head of each reach at a constant rate. According to the data sets of tracer experiments, mechanisms of ammonium and phosphorus retention were interpreted by using OTIS model code, transient storage metrics and nutrient spiraling theory. Study results showed that: (1) The value of As in deep pool was larger than that in winding ditch, whereas its value of hydrological parameter α was lower by an order of magnitude than that of winding ditch; (2) The value of NH(4)+ -λ in main channel was higher by two to three orders of magnitude than that of NH(4)+ -λs,in transient storage zone in deep pool, but in winding ditch the two parameters were closer in terms of numerical size; (3) In deep pool, the value of NH+(4) -Vf was higher by an order of magnitude than that of SRP-Vf, in winding ditch, however, not only the two values of NH(4)+ -Vf and SRP-Vf were close to each other, but NH(4)+ -Sw was nearly equal to SRP-Sw in numerical size as well; (4) The value of NH(4)+ -U was larger by two to three orders of magnitude than that of SRP-U in deep pool, whereas in winding ditch NH(4)+ -U was just larger by one to two orders of magnitude than SRP-U in size; (5) In general, significant difference existed between deep pool and winding ditch in the effect on ammonium and phosphorus retention, and marked retention efficiency was observed for ammonium rather than SRP in deep pool.

[Nitrogen and phosphate pollution characteristics and eutrophication evaluation for typical urban landscape waters in Hefei City].

To understand the water environment regimes of the city-circling water system in Hefei City, six typical landscape waters were chosen to investigate pollution characteristics of nitrogen and phosphate and evaluate water eutrophication level according to the monitoring data of water physicochemical characteristics and chlorophyll content from September 2012 to July 2013. Study results showed that (1) the six waters mentioned above have been seriously polluted by nitrogen and phosphorus loadings, with the monthly mean values of total nitrogen (TN) and total phosphorus (TP) concentrations far exceeding the universally accepted threshold values of water eutrophication; (2) the nitrogen contents in the waters of Nanfeihe River, Heichiba and Yuhuatang scenic spots exhibited a markedly monthly variation, and both TP and PO(3-)(4)-P in Nanfeihe River showed a fluctuated characteristic with high concentrations while presenting a significant upward trend in Yuhuatang scenic spot; (3) the average values of TN/TP ratios for Yuhuatang and Heichiba scenic spots were 104.7 and 158.

Head and neck cancer patients want us to support them psychologically in the posttreatment period: Survey results.

Objectives: No study systematically has investigated the supportive care needs of general head and neck cancer patients using validated measures. These needs include physical and daily living needs, health system and information needs, patient care and support needs, psychological needs, and sexuality needs. Identifying the unmet needs of head and neck cancer patients is a necessary first step to improving the care we provide to patients seen in our head and neck oncology clinics.

A new RNA-seq method to detect the transcription and non-coding RNA in prostate cancer.

Prostate cancer is a big killer in many regions especially American men, and this year, the diagnosed rate rises rapidly. We aimed to find the biomarker or any changing in prostate cancer patients. With the development of next generation sequencing, much genomic alteration has been found.

Endoscopic expand transnasal approach to the suprasellar region: anatomical study and clinical considerations.

Background: The expanded endonasal approach (EEA) is used sparingly by surgeons for resection of lesions in the ventrocranial base. Herein, we examined the anatomy of the ventrocranial base by endoscopy and comment on the use of EEA in clinical practice.

Methods: Twenty artery-injected adult cadaveric heads were studied under surgical conditions using the endoscopic EEA.