[Effects of IAA on physiological response to aluminum stress and DNA damage of ].

To investigate the physiological response of IAA (indoleacetic acid) to under aluminum stress and the mitigation of DNA damage, the effects of IAA (0, 10, 25, 50, 75 μmol·L denoted by I, I, I, I and I, respectively) on antioxidant enzyme activity, malondialdehyde (MDA), photosynthetic characteristics, root activity, chlorophyll content and DNA damage of two varieties of under 300 and 800 μmol·L aluminum environment (denoted by Al and Al, respectively) were examined in hydroponic culture experiments with Hebei Anguo (aluminium tolerant variety) and Zhejiang Puyang (aluminum sensitive variety). The results showed that the activities of superoxide dismutase (SOD), peroxidase (POD) and catalase (CAT), photosynthesis ability, and root activity of both varieties were inhibited to different degrees by aluminum stress, MDA content was significantly increased, and DNA damage was aggravated. The maximum increase of SOD, CAT and POD activities in Anguo and Puyang under aluminum stress by IAA application were 15.

Cyclosporine A improves adhesion and invasion of mouse preimplantation embryos via upregulating integrin β3 and matrix metalloproteinase-9.

Our previous study has demonstrated cyclosporin A (CsA) promotes the migration and invasiveness of human first-trimester trophoblast cells in vitro. Here, we further investigated the effect of CsA on the early implantation in vitro of mouse embryo. Female C57 mice were superovulated and mated, and then two-cell embryos were harvested from the oviducts and sequentially cultured in vitro in G1 and G2 media with 0, 0.