Publications by authors named "Ji-Ling Li"
Objective: This study aimed to identify a DLX3 gene mutation in a family with atypical clinical manifestations of tricho-dento-osseous syndrome (TDO) and its impact on tooth enamel thickness, microhardness, structure and formation.
Design: Whole-exome sequencing detected DLX3 mutations in the family. Micro-CT, Vickers hardness tester, energy dispersive spectrometer and scanning electron microscopy were performed on the deciduous teeth of the proband and controls.
Objective: The aim of this study was to explore the regulatory effect of RUNX2 mutation on dental follicle cells (DFCs) senescence and clarify the underlying mechanism. This study aimed to explore the basis for a novel mechanism of delayed permanent tooth eruption in cleidocranial dysplasia (CCD) patients.
Materials And Methods: Dental follicles were collected from a CCD patient and healthy controls.
Article Synopsis
- The study investigates the use of conditioned medium from placenta-derived mesenchymal stem cells (PMSC-CM) as a storage solution for avulsed teeth to improve the viability of periodontal ligament cells.
- Results showed that PMSC-CM significantly reduced the apoptosis rate of these cells compared to Hank's balanced salt solution (HBSS) after 24 hours, indicating better cell preservation.
- Additionally, PMSC-CM enhanced the proliferation of human periodontal ligament stem cells (PDLSCs) compared to HBSS, suggesting it could be a more effective medium for storing avulsed teeth prior to replantation.
Objective: To characterize the profile of chromosomal imbalances in esophageal cancer (EC) with or without family history in Linzhou, Henan Province of China.
Methods: Comparative genomic hybridization (CGH) was used to examine 13 cases with positive family history of EC and 32 cases with negative family history of EC. RESULTS DNA copy number gains on chromosome 10q was observed only in the cases with postivie family history of EC (30%), and none in cases with a negative family history (P<0.