Proc Natl Acad Sci U S A
November 2023
The unexpected discovery of hot Jupiters challenged the classical theory of planet formation inspired by our solar system. Until now, the origin and evolution of hot Jupiters are still uncertain. Determining their age distribution and temporal evolution can provide more clues into the mechanism of their formation and subsequent evolution.
View Article and Find Full Text PDFBackground: The prevalence of diabetes mellitus (DM) in China is high, and the base is broad. Diabetic retinopathy (DR) is a critical condition affecting the life and health of a nation and its economic development. DR is a common complication of DM.
View Article and Find Full Text PDFWe discover a population of short-period, Neptune-size planets sharing key similarities with hot Jupiters: both populations are preferentially hosted by metal-rich stars, and both are preferentially found in systems with single-transiting planets. We use accurate Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST) Data Release 4 (DR4) stellar parameters for main-sequence stars to study the distributions of short-period [Formula: see text] planets as a function of host star metallicity. The radius distribution of planets around metal-rich stars is more "puffed up" compared with that around metal-poor hosts.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
October 2016
The nearly circular (mean eccentricity [Formula: see text]) and coplanar (mean mutual inclination [Formula: see text]) orbits of the solar system planets motivated Kant and Laplace to hypothesize that planets are formed in disks, which has developed into the widely accepted theory of planet formation. The first several hundred extrasolar planets (mostly Jovian) discovered using the radial velocity (RV) technique are commonly on eccentric orbits ([Formula: see text]). This raises a fundamental question: Are the solar system and its formation special? The Kepler mission has found thousands of transiting planets dominated by sub-Neptunes, but most of their orbital eccentricities remain unknown.
View Article and Find Full Text PDFConf Proc IEEE Eng Med Biol Soc
September 2008
To study the effects of 4-hydroxy-2-nonenal (HNE) on cultured human aortic endothelial cells and myocardial cells so as to explore the mechanism of the pathogenesis of atherosclerosis. In situ cell death technique, quantitative DNA damage detection and immunohistochemistry were used to identify the cell apoptosis and DNA damage in cultured human aortic endothelial cells and myocardial cells. Tail moment was 32.
View Article and Find Full Text PDFAim: To investigate the mRNA expressions of bFGF and MMP-9 in gastric carcinomas so as to reveal their correlations with tumor microvascular density (MVD), invasion, metastasis, and prognosis.
Methods: In situ hybridization and immunohistochemical techniques were used to detect the expressions of bFGFmRNA and MMP-9mRNA and the proteins of CD34 in 105 specimens of gastric carcinomas.
Results: In situ hybridization study showed that positive rates of bFGF mRNA and MMP-9mRNA expressions were 60.
Chin Med J (Engl)
October 2004
Background: The aim of this study was to investigate DNA content and expression of c-erbB-2, PS2, and prostate-specific antigen (PSA) proteins in breast carcinomas with neuroendocrine (NE) cell differentiation.
Methods: Chromogranin, c-erbB-2, PS2, and PSA in 131 samples of breast cancer were detected immunohistochemically. Classic Feulgen staining image analysis techniques were used to quantify DNA content in 81 of the breast cancer samples.
To evaluate protection of vitamin C on blue light-induced DNA damage of human retinal pigment epithelium (RPE) cells. The cultured RPE cells were divided into 3 groups: Control group (no blue light exposure), blue light exposure group (blue light exposure for 20 minutes) and blue light exposure + vitamin C group (blue light exposure + 100 mumol/L vitamin C). Travigen's comet assay kit and Euclid comet assay software were used to assay the DNA damage levels.
View Article and Find Full Text PDFZhongguo Yi Xue Ke Xue Yuan Xue Bao
April 2003
Objective: To investigate the relationship between diabetes and somatostatin (SOM).
Methods: We established a streptozocin-induced diabetic rats model and studied the changes of SOM mRNA in hippocampi of diabetic and normal rats by using in situ hybridication and computer image analysis. We studied the mechanism of chronic diabetes encephalopathy by observing the changes of somatostatin mRNA in the hippocampus of diabetic rats was studied.
World J Gastroenterol
April 2003
Aim: To investigate the incidence of neuroendocrine (NE) cells and their hormone products in adenocarcinomas and evaluate their significance in clinical pathology and prognosis.
Methods: By using tissue sectioning and immunocyto-chemistry, 356 cases of adenocarcinomas were studied to examine the presence of chromorgranin and polypeptide hormones in adenocarcinoma samples from our hospital.
Results: The positive rate of NE cells and hormone products was 41.
Zhejiang Da Xue Xue Bao Yi Xue Ban
August 2002
OBJECTIVE: To provide the anatomical basis for the repair of the soft tissue defects on the dorsum of the foot. METHODS: Sixty-eight low extremity specimens were taken from fresh cadavers. The arterial distributions of the foot were observed by perfusing red latex, barium sulfate, Chinese ink and 10% gelatin, also studied by X-ray angiography and microdissection.
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