[Medium and long-term outcomes of laparoscopic right hemicolectomy for colon cancer].

Objective: To evaluate factors associated with postoperative survival after laparoscopic right hemicolectomy for colon cancer.

Methods: Clinical data of patients undergoing laparoscopic right hemicolectomy in the Department of General Surgery, the Peking University Third Hospital from February 2004 to March 2011 were obtained and analyzed. Kaplan-Meier method was used to calculate survival rate and univariate analysis was performed.

[Multi-slice spiral computed tomography angiography for preoperative evaluation of laparoscopic right hemicolectomy].

Objective: To explore the application value of multi-slice spiral CT angiography (MSCTA) for the preoperative evaluation of laparoscopic right hemicolectomy.

Methods: Abdominal CT slice images of 160 patients(group A) were collected for 3-dimensional reconstruction using volume rendering technique. Interpretation and anatomical classification of the major branches and course of the superior mesenteric artery(SMA) in the reconstructed images of the arterial phase were carried out.

Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML.

Arsenic, an ancient drug used in traditional Chinese medicine, has attracted worldwide interest because it shows substantial anticancer activity in patients with acute promyelocytic leukemia (APL). Arsenic trioxide (As2O3) exerts its therapeutic effect by promoting degradation of an oncogenic protein that drives the growth of APL cells, PML-RARalpha (a fusion protein containing sequences from the PML zinc finger protein and retinoic acid receptor alpha). PML and PML-RARalpha degradation is triggered by their SUMOylation, but the mechanism by which As2O3 induces this posttranslational modification is unclear.