Publications by authors named "Ji-Hua Zhao"

Two-dimensional (2D) CsPbBr exhibits intriguing functions in enhancing the performance of optoelectronic devices in terms of environmental stability and luminescence properties when composited with other perovskites in different dimensionalities. We built a type I three-dimensional (3D) CsPbBr/2D CsPbBr heterojunction through phase transition where CsPbBr quantum dots in situ grew into 2D CsPbBr. A thorough growth mechanism study in combination with excited state dynamic investigations via femtosecond spectroscopy and first-principles calculations revealed that the type I hierarchy enhanced the stability of the heterojunction and spurred its luminous quantum yield by prolonging the lifetime of photogenerated carriers.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to investigate the changes in MET-related gene expression during the transformation of bone marrow mesenchymal stem cells (MSCs) into neuron-like cells and identify the underlying molecular mechanisms.
  • Researchers used specific chemical agents (BHA and DMSO) to induce this transformation and analyzed the cells' gene expression and proliferation using comparative PCR and flow cytometry.
  • The results showed decreased expression of MET-associated transcription factors, an increase in the mesenchymal marker Vimentin, and a significant reduction in cell proliferation, suggesting that the Wnt/β-catenin pathway plays a role in this trans-differentiation process.
View Article and Find Full Text PDF

Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases responsible for degrading essentially all components of the extracellular matrix (ECM). Accumulating evidence suggests that MMPs might play a critical role in growth, invasion, and metastasis of malignant tumors. A single nucleotide polymorphism (SNP) in the promoter region of MMP-12, MMP-12 82 A/G (rs2276109), has been recognized to play a critical role in regulating the expression of MMP-12, however, its correlation with tumor susceptibility remains controversial.

View Article and Find Full Text PDF

There is growing evidence suggesting that cancer stem cells (CSCs) are playing critical roles in tumor progression, metastasis and drug resistance. However, the role of CSCs in non-small cell lung cancer (NSCLC) remains elusive. In this study, we enriched for stem-like cells from tumor spheres derived from NSCLC cell line A549 cultured in serum-free medium.

View Article and Find Full Text PDF

Neurensin-2 (NRSN2), a small neural membrane protein which localized in small vesicles in neural cells. Recent report suggested that Neurensin-2 might play a suppressive role in tumor. While the biological functions and molecular mechanisms in cancer progression remain unknown.

View Article and Find Full Text PDF

Objective: To analyze defective homologous chromosomal recombination in Han Chinese azoospermic patients.

Methods: Testicular biopsy samples from 7 healthy controls and 7 Han Chinese azoospermic patients including 2 obstructive azoospermia (OA group) and 5 non-obstructive azoospermia (NOA group) were analyzed. Immunofluorescence staining was performed to categorize early stage cells at meiosis prophase and to analyze chromosome pairing and recombination of pachytene spermatocyte.

View Article and Find Full Text PDF

Objective: To investigate the influence on developmental potential of frozen-thawed rabbit oocytes with double assisted activation followed by intracytoplasmic sperm injection (ICSI).

Methods: A total of rabbit oocytes were collected and thawed after vitrification cryopreservation. Among all oocytes were cultured for 1 hour followed by ICSI.

View Article and Find Full Text PDF

Objective: To examine the metaphase II spindle and chromosome configurations of human oocytes cultured for different times after thawing.

Methods: Using slow-cooling and raid-thawing protocol combined with 0.3 mol/L sucrose and 1.

View Article and Find Full Text PDF