Publications by authors named "Ji-Hai Shi"
Article Synopsis
- - The study involved 1,688 Chinese patients with metastatic colorectal cancer (mCRC) across 19 hospitals to investigate the use of targeted therapies and the barriers they face in accessing these treatments.
- - About 51.6% of patients began targeted therapy, with varying rates of first-, second-, and third-line treatments; common barriers included high costs and doubts about treatment effectiveness.
- - Factors making patients less likely to start targeted therapy included older age, lower education and income levels, lack of medical insurance, and having more severe health issues; addressing cost and enhancing public education could improve treatment access.
Background: Biomarkers are a key tool in early detection, prognostication, survival, and predicting treatment response of colorectal cancer (CRC). However, little is known about biomarker testing for CRC patients in real-life clinical practice in China. This study aimed to address the usage of biomarker testing and analyze factors related to its acceptance among Chinese patients with advanced CRC.
View Article and Find Full Text PDFBackground: Colorectal cancer (CRC) causes a substantial disease burden in China. Information on the medical expenditure of CRC patients is critical for decision-makers to allocate medical resources reasonably, however, relevant data is limited in China, especially advanced CRC. The aim of this survey was to quantify the out-of-pocket medical expenditure of advanced CRC and explore associated factors.
View Article and Find Full Text PDFBackground: The imbalanced allocation of medical resources leads to the occurrence of cross-regional healthcare-seeking in China. Due to the low cure rate, advanced colorectal cancer (CRC) patients may seek cross-regional healthcare for high-level medical facilities. Investigating status of cross-regional healthcare-seeking and its associated factors among advanced CRC patients is important for policymakers to understand access to health services and improve the quality of oncology services.
View Article and Find Full Text PDFObjective: The aim of this study is to systematically evaluate the clinical efficacy and safety of the traditional Chinese medicine prescription Jade Screen combined with desloratadine in the treatment of chronic urticaria.
Methods: Two researchers independently conducted literature searches. The extracted data were analyzed using Rev Man 5.
[Effects of baicalin and other Chinese herbal monomer on androgen receptor mRNA expression in SZ95 sebocytes].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
April 2007
Objective: To determine the effects of Chinese herbal monomers such as baicalin, berberine, and matrine on the androgen receptor (AR) mRNA expression in SZ95 sebocytes in vitro and to explore the possible mechanism of using traditional Chinese medicines to treat acne.
Methods: SZ95 sebocytes were cultured and then treated with berberine, baicalin, matrine, and 13-cis-retinoic acid for 24 hours. Reverse transcription polymerase chain reaction was applied to detect the changes of AR.