Publications by authors named "Ji-Feng He"
Adv Clin Exp Med
October 2024
Article Synopsis
- Novel treatments have improved survival rates for hepatocellular carcinoma (HCC) patients, but resistance to these therapies is a key challenge, highlighting the need for research into drug resistance mechanisms.
- The study focuses on the tyrosine kinase inhibitor (TKI)-resistant gene ZNF687, examining its role and clinical significance in HCC through various bioinformatics and molecular analysis techniques.
- Results indicate that ZNF687 is overexpressed in HCC and linked to poorer patient outcomes, with histone modification and related pathways identified as significant, alongside the compound chaetocin showing potential against ZNF687.
