Publications by authors named "Ji-Fen Fu"
Article Synopsis
- Immune and inflammatory responses play a crucial role in pulmonary hypertension (PH), yet the immune system's response in patients with high-altitude pulmonary hypertension (HAPH) is not well understood.
- * Using single-cell transcriptomics, the study identifies significant changes in monocyte populations in the blood of HAPH patients, particularly increases in non-classical (C1) and intermediate (C2) monocytes.
- * The findings suggest that decreased levels of hypoxia-inducible transcription factor-1α (HIF-1α) in all monocyte types may be linked to the development of HAPH, highlighting a potential immune-related mechanism in this condition.*
