Three-dimensional microengineered vascularised endometrium-on-a-chip.

Study Question: Can we reconstitute physiologically relevant 3-dimensional (3D) microengineered endometrium in-vitro model?

Summary Answer: Our representative microengineered vascularised endometrium on-a-chip closely recapitulates the endometrial microenvironment that consists of three distinct layers including epithelial cells, stromal fibroblasts and endothelial cells in a 3D extracellular matrix in a spatiotemporal manner.

What Is Known Already: Organ-on-a-chip, a multi-channel 3D microfluidic cell culture system, is widely used to investigate physiologically relevant responses of organ systems.

Study Design, Size, Duration: The device consists of five microchannels that are arrayed in parallel and partitioned by array of micropost.

CXCL12 enhances pregnancy outcome via improvement of endometrial receptivity in mice.

Successful pregnancy inevitably depends on the implantation of a competent embryo into a receptive endometrium. Although many substances have been suggested to improve the rate of embryo implantation targeting enhancement of endometrial receptivity, currently there rarely are effective evidence-based treatments to prevent or cure this condition. Here we strongly suggest minimally-invasive intra-uterine administration of embryo-secreted chemokine CXCL12 as an effective therapeutic intervention.

Pathological Evaluation of Radiation-Induced Vascular Lesions of the Brain: Distinct from De Novo Cavernous Hemangioma.

Purpose: We aimed to evaluate the histologic and radiologic findings of vascular lesions after stereotactic radiosurgery (SRS) categorized as radiation-induced cavernous hemangioma (RICH).

Materials And Methods: Among 89 patients who underwent neurosurgery for cavernous hemangioma, eight RICHs from 7 patients and 10 de novo CHs from 10 patients were selected for histopathological and radiological comparison.

Results: Histologically, RICHs showed hematoma-like gross appearance.

Analysis of cyclic pyrolysis products formed from amino acid monomer.

Amino acid was mixed with silica and tetramethylammonium hydroxide (TMAH) to favor pyrolysis of amino acid monomer. The pyrolysis products formed from amino acid monomer were using GC/MS and GC. 20 amino acids of alanine, arginine, asparagine, aspartic acid, cysteine, glutamic acid, glutamine, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine, threonine, tryptophan, tyrosine, and valine were analyzed.

Study on the structural and photocatalytic properties for pore size tailored SnO2-pillared layered titanate nanohybrids.

A new mesoporous SnO2-pillared layered titanate is prepared by hybridizing the exfoliated titanate nanosheets with SnO2 nanosol particles. The pore size tailored porous nanohybrids (SBET = 74 approximately 280 m2/g and d = 18 approximately 96 angstroms) are obtained after calcining an as-prepared sample. The mesoporous nanohybrids exhibited different photocatalytic behaviors for salicylic acid and methylene blue depending upon their crystallinity and porous structure.