Publications by authors named "Ji-Eun Irene Yum"
Article Synopsis
- Platelet-rich plasma (PRP) is derived from a person's own blood and is thought to aid in the healing of injuries by concentrating platelets, growth factors, and cytokines through a centrifugation process.
- * The paper reviews existing clinical studies on PRP injections specifically targeting the lumbar spine to assess their effectiveness in treating lower back pain, a major cause of disability among patients.
- * Although many studies support the use of PRP in various lumbar injection techniques, some research indicates it may not significantly alleviate back pain, highlighting the need for more rigorous, well-designed clinical trials to determine its true efficacy.
Background: Mutations in PIEZO1 (Piezo type mechanosensitive ion channel component 1) cause human lymphatic malformations. We have previously uncovered an ORAI1 (ORAI calcium release-activated calcium modulator 1)-mediated mechanotransduction pathway that triggers lymphatic sprouting through Notch downregulation in response to fluid flow. However, the identity of its upstream mechanosensor remains unknown.
View Article and Find Full Text PDFVISTA is an up-and-coming immune checkpoint molecule that can become the target of new cancer immunotherapy treatments. Immune cells in the tumor microenvironment can largely influence the progression of cancer through inhibitory and stimulatory pathways. Indeed, VISTA is expressed on many immune cells, including T cells, myeloid-derived suppressor cells, tumor-associated macrophages, and dendritic cells.
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