Protective effects of curcumin on acrolein-induced neurotoxicity in HT22 mouse hippocampal cells.

Background: Aging is one of the most important inevitable risk factors of Alzheimer disease (AD). Oxidative stress plays a critical role in the process of aging. Curcumin has been proposed to improve neural damage, especially neurodegenerative injury, through its antioxidant and anti-inflammatory properties.