Dual Photoswitching of a Diarylethene Ligand-Anchored Hofmann-Type Spin-Crossover Compound.

A diarylethene ligand-anchored two-dimensional Hofmann-type compound [Fe(BTEPy){Pt(CN)}](CHOH) (BTEPy = 1,2-bis[2-methyl-5-(4-pyridyl)-3-thienyl]cyclopentene) is synthesized, which undergoes a two-step spin-state transition and dual photoinduced magnetic switching.

Proton-Induced Reversible Spin-State Switching in Octanuclear Fe Spin-Crossover Metal-Organic Cages.

Responsive spin-crossover (SCO) metal-organic cages (MOCs) are emerging dynamic platforms with potential for advanced applications in magnetic sensing and molecular switching. Among these, Fe-based MOCs are particularly noteworthy for their air stability, yet they remain largely unexplored. Herein, we report the synthesis of two novel Fe MOCs using a bis-bidentate ligand approach, which exhibit SCO activity above room temperature.

Identification of Dynamic Active Sites Among Cu Species Derived from MOFs@CuPc for Electrocatalytic Nitrate Reduction Reaction to Ammonia.

Direct electrochemical nitrate reduction reaction (NITRR) is a promising strategy to alleviate the unbalanced nitrogen cycle while achieving the electrosynthesis of ammonia. However, the restructuration of the high-activity Cu-based electrocatalysts in the NITRR process has hindered the identification of dynamical active sites and in-depth investigation of the catalytic mechanism. Herein, Cu species (single-atom, clusters, and nanoparticles) with tunable loading supported on N-doped TiO/C are successfully manufactured with MOFs@CuPc precursors via the pre-anchor and post-pyrolysis strategy.

One-Step versus Two-Step Valence Tautomeric Transitions in Tetraoxolene-Bridged Dinuclear Cobalt Compounds.

The syntheses of valence tautomeric compounds with multistep transitions using new redox-active ligands are the long-term goal of the field of bistable materials. The redox-active tetraoxolene ligand, 2,7-di--butylpyrene-4,5,9,10-tetraone (pyrene), is now developed to synthesize a pair of dinuclear compounds {[CoL](pyrene)}[Co(CO)]·CHCl·2CHCH (, = 2, L = 1,10-phenanthroline, phen; , = 1.5, L = 2,2'-bipyridine, bpy).

Long non-coding RNA SNHG6 promotes glioma tumorigenesis by sponging miR-101-3p.

Introduction: Glioma is the most common primary brain tumor. The small nucleolar RNA host gene (SNHG) SNHG6 is a potential oncogene in the development of several types of cancers.

Methods: In this study, we investigated the functional role of long non-coding RNA (lncRNA) SNHG6 in the malignancy of glioma in cell lines and transplanted nude mice.

Use of Hydrogen as a Novel Therapeutic Strategy Against Photoreceptor Degeneration in Retinitis Pigmentosa Patients.

Retinitis pigmentosa (RP) is a heterogeneous group of inherited retinal dystrophies characterized by progressive photoreceptor apoptosis. Reactive oxygen species (ROS) have been recognized as critical initiators of the photoreceptor apoptosis in RP. Photoreceptor survival in RP mutants will not only require the inhibition of effectors of apoptotic machinery, but also the elimination of the initiating upstream signals, such as ROS.