The Prediction of Bronchopulmonary Dysplasia in Very Low Birth Weight Infants through Clinical Indicators within 1 Hour of Delivery.

Background: Despite the advances in neonatology, the incidence of bronchopulmonary dysplasia (BPD) is increasing. It is important to prevent the development of BPD in the first place. The online BPD outcome estimator from National Institute of Children Health and Human Development and Neonatal Research Network is available.

Temperature-dependent chirality of cholesteric liquid crystal for terahertz waves.

Recently, the terahertz (THz) chiral field control opens a new window to THz devices and their applications. In this Letter, the active manipulation for THz chiral states based on the cholesteric liquid crystal (CLC) has been demonstrated by THz time domain cross-polarization spectroscopy. The results show that the CLC has strong THz optical activity and circular dichroism (CD) effect, and the strongest THz CD of 22 dB and a polarization rotation angle of 88.

Terahertz birefringence anisotropy and relaxation effects in polymer-dispersed liquid crystal doped with gold nanoparticles.

Terahertz (THz) birefringence anisotropy of the polymer-dispersed liquid crystal (PDLC) doped with gold nanoparticles (Au NPs) is investigated by using terahertz time domain polarization spectroscopy. Controlled by the electric field, the change rate of refractive index for PDLC doped with Au NPs is 0.91% V as the voltage increases, smaller than the pure PDLC, which indicates that the response of the PDLC doped with Au NPs to electric field is more uniform than that of pure PDLC.

Terahertz resonance switch induced by the polarization conversion of liquid crystal in compound metasurface.

We experimentally demonstrate an active terahertz (THz) resonance switch induced by the polarization conversion in a compound metasurface, which is a LC layer sandwiched by a metallic wire grating and resonance metamaterial (LCGM). Here, the liquid crystal (LC) plays the role of polarization conversion, which can induce the TE resonance. Moreover, there exists a localized resonance between metallic grating and metamaterial layers, and then the excited resonance will be greatly enhanced.

Broadband controllable terahertz quarter-wave plate based on graphene gratings with liquid crystals.

Developing the broadband controllable or tunable terahertz (THz) polarization and phase devices are in an urgent need. In this paper, we demonstrate a broadband controllable THz quarter-wave plate (QWP) with double layers of graphene grating and a layer of liquid crystals. The double layer graphene gratings can achieve a switchable QWP to switch between linear-to-linear and linear-to-circular polarization states with over 0.

Prognostic implications of and status in esophageal squamous cell carcinoma.

Aim: To investigate the clinicopathological features and prognostic implications of combined MYC and fibroblast growth factor receptor 1 () status in esophageal squamous cell carcinomas (ESCCs).

Methods: All patients with ESCC ( = 180) underwent surgical resection at Seoul National University Hospital sometime between 2000 and 2013. A tissue microarray was constructed using cores obtained from representative tumor areas of formalin-fixed, paraffin-embedded tissue blocks.

PELI1 expression is correlated with MYC and BCL6 expression and associated with poor prognosis in diffuse large B-cell lymphoma.

PELI is a family of E3 ubiquitin ligases that regulate protein activity through a post-translational modification, ubiquitination. While PELI1 has been found to play a pivotal role in inflammatory processes through the activation of Toll-like receptor signaling and the NF-kB pathway, the role of PELI1 in oncogenesis has not been the subject of much investigation. We aimed to explore PELI1 expression in various malignant lymphomas and identify clinicopathologic significance.

MYC overexpression correlates with MYC amplification or translocation, and is associated with poor prognosis in mantle cell lymphoma.

Aims: We aimed to investigate MYC expression and chromosomal aberration in mantle cell lymphoma (MCL), and the clinical significance of these factors.

Methods And Results: Sixty-five patients with MCL, including 54 classic, nine blastoid and two pleomorphic variants, were enrolled. Expression of MYC, Ki67 and p53 was assessed by immunohistochemistry.

Sonic hedgehog signalling proteins are frequently expressed in retinoblastoma and are associated with aggressive clinicopathological features.

Aims: This study aimed to examine the expression of Sonic hedgehog (SHH) signalling proteins in retinoblastoma and to evaluate its clinical significance.

Methods: Seventy-nine enucleated retinoblastoma tumours were investigated immunohistochemically using antibodies against SHH pathway proteins, such as SHH, glioma-associated oncogene homologue (GLI) 1, GLI2, GLI3 and ABC binding cassette G2 (ABCG2). Western blotting of SHH signalling proteins was performed in two retinoblastoma cell lines.

Indoleamine 2,3-dioxygenase (IDO) is frequently expressed in stromal cells of Hodgkin lymphoma and is associated with adverse clinical features: a retrospective cohort study.

Background: Regulation of tumor microenvironment is closely involved in the prognosis of Hodgkin lymphoma (HL). Indoleamine 2,3-dioxygenase (IDO) is an enzyme acting as immune modulator through suppression of T-cell immunity. This study aims to investigate role of IDO in the microenvironment of HL.

Expression of cancer stem cell markers is more frequent in anaplastic thyroid carcinoma compared to papillary thyroid carcinoma and is related to adverse clinical outcome.

Background: Thyroid cancer is one of the most commonly detected cancers worldwide, and papillary thyroidal carcinoma (PTC) accounts for the majority of thyroid cancers. In contrast to the indolent nature of PTC, anaplastic thyroid carcinoma (ATC) shows an extremely poor prognosis and has not responded to any therapeutic modalities. Many researchers postulate that the dedifferentiation of thyroid follicular cells into primitive cells might be related to the pathogenesis of ATC because several cases of ATC have revealed pre-existing PTC lesions.

Inflammatory pseudotumor-like follicular dendritic cell sarcoma of the spleen: a report of six cases with increased IgG4-positive plasma cells.

Inflammatory pseudotumor (IPT)-like follicular dendritic cell (FDC) sarcoma is a rare neoplasm typically occurring in the spleen or liver. We present six cases of EBV(+) IPT-like FDC sarcoma of the spleen among Koreans along with their clinicopathologic features and IHC results. Most patients presented with an asymptomatic, incidentally detected single splenic mass and were successfully managed by splenectomy alone.

Expression of c-Met Is Different along the Location and Associated with Lymph Node Metastasis of Head and Neck Carcinoma.

Background: Activation of the c-Met pathway is involved in cancer progression and the prognosis. We aimed to identify any association of c-Met protein expression with a number of clinicopathologic variables including infection of human papillomavirus and Epstein-Barr virus (EBV) in head and neck carcinomas (HNCa).

Methods: Eighty-two cases were enrolled in this study.