Closed-incision negative pressure wound therapy (NPWT) in elderly patients following sacral pressure sore reconstruction.

Background: Pressure sores significantly affect elderly patients, with the sacrum being especially vulnerable, often due to its proximity to the anus and potential for fecal contamination. Despite preventive measures such as frequent repositioning and specialized cushions, some sores still necessitate surgical intervention. Postoperative care focuses on monitoring, hygiene, and pressure alleviation.

Efficacy of Nd:YAG Laser and Intralesional Triamcinolone Injection Combination Therapy in the Postoperative Management of Keloids.

Background: Keloids, characterized by protruding scars that extend beyond the original skin damage site, cause significant emotional stress and reduced quality of life. Their exact pathogenesis remains unclear, with various hypotheses including growth factor imbalances and extracellular matrix changes. No single treatment is universally accepted, but multiple modalities like triamcinolone acetonide injection (TAC), laser therapies, and surgery are commonly used.

sp. nov., a paraoxon-degrading bacterium isolated from red pepper cultivation soil.

A bacterial strain designated MMS21-TAE1-1, capable of degrading paraoxon, was isolated from red pepper soil (36° 25' 26.0″ N, 126° 25' 47.0″ E) and subjected to polyphasic taxonomic characterisation.

Advanced Facial Rejuvenation: Synergistic Effects of Lower Blepharoplasty and Ultrasound Guided Mid-Face Lift Using Polydioxanone (PDO) Threads.

Background: Traditional facial aging surgeries have risks and extended recovery times, leading to a demand for minimally invasive alternatives. PDO (polydioxanone) threads, which are absorbable sutures that stimulate collagen production and tissue contraction, offer improved aesthetic outcomes. This paper evaluates the combined use of PDO thread mid-cheek lift and lower blepharoplasty for facial rejuvenation.

Discovery of N-(1-(2-hydroxyethyl)quinolin-2-one)-N'-(1-phenyl-1H-pyrazol-5-yl)methyl) urea as Mode-Selective TRPV1 antagonist.

To discover mode-selective TRPV1 antagonists as thermoneutral drug candidates, the previous potent antagonist benzopyridone 2 was optimized based on the pharmacophore A- and C-regions. The structure activity relationship was investigated systematically by modifying the A-region by incorporating a polar side chain on the pyridone and then by changing the C-region with a variety of substituted pyridine and pyrazole moieties. The 3-t-butyl and 3-(1-methylcyclopropyl) pyrazole C-region analogs provided high potency as well as mode-selectivity.

sp. nov., exhibiting antimicrobial activity, isolated from mountain soil around a decaying tree.

A Gram-stain-positive, aerobic actinobacterial strain designated MMS17-BM035 isolated from mountain soil around a decaying tree was subjected to taxonomic characterization. The isolate developed extensively branched substrate mycelia and white aerial hyphae on International Project 2 agar. Strain MMS17-BM035 grew at 15-34 °C (optimum, 30 °C), at pH 5.

sp. nov., isolated from bamboo grove soil.

A bacterial strain designated BG109 was isolated from bamboo grove soil, and subjected to polyphasic taxonomic characterization. BG109 is an aerobic, non-motile, Gram-stain-positive and endospore-forming bacterium. BG109 showed growth at 10-40 °C (optimum, 37 °C), at pH 4-10 (optimum, 8), and in the presence of 0-7 % NaCl concentration (optimum, 0-1 %).

sp. nov. and sp. nov., two new endophytic bacterial species isolated from plant roots.

Two Gram-positive, endospore-forming, rod-shaped bacterial strains designated MWE-103 and DLE-14 were isolated from plant roots. The 16S rRNA gene sequence analysis indicated that strain MWE-103 was closely related to SY01 with a sequence similarity of 97.82 %, and strain DLE-14 to IZS3-5 with 99.

sp. nov., exhibiting antimicrobial potential, isolated from riverside soil.

An actinobacterial strain designated MMS20-R1-14 was isolated from a riverside soil sample. Colonies on agar plates were orange to strong orange brown in colour, which later became black. The cells grew at 10-40 °C (optimum, 37 °C), pH 5.

sp. nov. and sp. nov., isolated from soil.

Two Gram-staining-negative, aerobic, rod-shaped bacteria designated strains SR9 and UL070, were isolated from soil and subjected to taxonomic characterization. Strain SR9 grew at 10-37 °C (optimum 30 °C), at pH 4.0-10.

Algorithmic intraocular lens power calculation formula selection by keratometry, anterior chamber depth and axial length.

Purpose: To compare the prediction accuracy of algorithmic intraocular lens (IOL) power calculation formula selection method using conventional formulas (Haigis, Hoffer Q, Holladay 1, SRK/T and/or Barrett Universal II) based on keratometry (K), anterior chamber depth (ACD) and axial length (AL).

Methods: A total of 1653 patients (1653 eyes) implanted with Tecnis ZCB00 IOL during cataract surgery were enrolled in this study. Intraocular lens (IOL) power calculation formulas with a small absolute value in the sum of the area under the curve measured by K, ACD and AL subgroup were selected to calculate IOL power in the relevant biometry subgroup.

Design of Chemically Stable Organic Perovskite Quantum Dots for Micropatterned Light-Emitting Diodes through Kinetic Control of a Cross-Linkable Ligand System.

Perovskite quantum dot (QD) light-emitting diodes (PeLEDs) are ideal for next-generation display applications because of their excellent color purity, high efficiency, and cost-effective fabrication. However, developing a technology for high-resolution multicolor patterning of perovskite QDs remains challenging, owing to the chemical instability of these materials. To overcome these issues, in this work, the generation of surface defects is prevented by controlling the ligand-binding kinetics using a stable ligand system (Stable LS).

Spermidine Attenuates Oxidative Stress-Induced Apoptosis via Blocking Ca Overload in Retinal Pigment Epithelial Cells Independently of ROS.

Retinal pigment epithelial (RPE) cells occupy the outer layer of the retina and perform various biological functions. Oxidative damage to RPE cells is a major risk factor for retinal degeneration that ultimately leads to vision loss. In this study, we investigated the role of spermidine in a hydrogen peroxide (HO)-induced oxidative stress model using human RPE cells.

Comparison of Nd:YAG Laser Capsulotomy Rates Between Refractive Segmented Multifocal and Multifocal Toric Intraocular Lenses.

Purpose: To investigate the early incidence of neodymium-doped yttrium aluminum garnet (Nd:YAG) laser capsulotomy according to intraocular lens (IOL) type (nontoric vs toric) and surgical techniques (femtosecond laser-assisted cataract surgery vs conventional phacoemulsification) in eyes with refractive multifocal IOLs.

Design: Retrospective case-control study.

Methods: Nine hundred thirteen eyes from 483 patients implanted with Lentis Mplus LS-313 MF20 (767 eyes) or Lentis Mplus Toric LU-313 MF20T (146 eyes) IOLs (Oculentis GmbH, Berlin, Germany) were enrolled.

Application of Silver Nanofluids on Kinetics of Sulfur Hexafluoride Gas Hydrate Formation.

Gas hydrates are nonstoichiometric nano-structured crystalline compounds which are stabilized by gas molecules incorporated in the cages made of hydrogen bonding of water molecules at suitable thermodynamic conditions. The gas hydrate as a technology has been successful for several potential applications in various engineering fields, such as, gas separation, carbon dioxide sequestration, gas storage and transportation, desalination of salt water and wastewater treatment. Recently, metal-based nanofluids are considered as interesting kinetic promoter candidates for accelerating formation of gas hydrates.

Protective effect of diphlorethohydroxycarmalol against oxidative stress-induced DNA damage and apoptosis in retinal pigment epithelial cells.

Reactive oxygen species (ROS) contribute to the onset and progression of disease pathogenesis in a variety of organs, including age-related macular degeneration (AMD). Diphlorethohydroxycarmalol (DPHC), a phlorotannin compound, is one of the major components of the brown alga Yendo, and has been shown to have strong antioxidant capacity. The purpose of this study was to evaluate the protective effects of DPHC against oxidative stress (hydrogen peroxide, HO)-induced DNA damage and apoptosis in cultured ARPE19 retinal pigment epithelial (RPE) cells.