Antibiotic-impregnated calcium sulfate for the treatment of pediatric hematogenous osteomyelitis.

Background: Antibiotic-impregnated calcium sulfate has excellent curative efficacy in chronic osteomyelitis. However, its curative efficacy in pediatric hematogenous osteomyelitis has not been sufficiently studied. The purpose of this study was to evaluate the curative effects of antibiotic-impregnated calcium sulfate in the treatment of pediatric hematogenous osteomyelitis.

Willingness to pay for and willingness to vaccinate with the COVID-19 vaccine booster dose in China.

The present study aims to assess the willingness to pay (WTP) for and willingness to vaccinate (WTV) with the Coronavirus (COVID-19) vaccine booster dose in China when the pandemic is under adequate control and the majority of the population is vaccinated. This study is also to identify significant factors associated with the WTP. This was a cross-sectional study on adults with no past or present COVID-19 infection.

Cost-effectiveness analysis of glecaprevir/pibrentasvir regimen for treating Chinese patients with chronic hepatitis C genotype 1 and genotype 2 infection.

Background: Hepatitis C virus (HCV) infection is an important health threat in China to which direct acting antivirals (DAAs) are very effective. In 2019, another novel DAA glecaprevir/pibrentasvir (GLE/PIB) was officially approved. Knowledge of its cost-effectiveness would be informative for clinical decision-making but has not been evaluated.

Culture-negative chronic hematogenous osteomyelitis in a two months old girl: a case report.

Background: Previous articles have focused on the diagnosis and treatment of acute hematogenous osteomyelitis. Here, we present a case of chronic hematogenous osteomyelitis in a 2-month-old girl. The diagnostic procedure was unusual and difficult due to negative culture results.

Finite Element Assessment of the Screw and Cement Technique in Total Knee Arthroplasty.

Background: The screw and cement technique is a convenient method used to rebuild medial tibial plateau defects in primary total knee arthroplasty (TKA). The objective of this study was to perform a finite element assessment to determine the effect of different numbers of screws on the stability of TKA and to determine whether differences exist between two different insertion angles.

Method: Six tibial finite element models with defects filled with screws and cement and one model with defects filled only with cement were generated.

Measurement of rotational alignment of the distal femur in total knee arthroplasty.

Objectives: To measure and compare the included angle between the surgical transepicondylar axis (STEA) and the posterior condylar line (PCL) and the included angle between the femoral anteroposterior line (APL) and PCL, and to discuss the value of STEA, APL, and PCL as rotational alignment landmarks of the distal femur in total knee arthroplasty (TKA).

Methods: Seventy-five normal femoral specimens from Chinese adult cadavers were randomly selected. An axial photograph of every femoral specimen was taken with a digital camera and put into a personal computer.

[Evaluation of perioperative blood loss following total knee arthroplasty].

Objective: To evaluate perioperative occult blood loss following total knee arthroplasty (TKA).

Methods: A retrospective analysis of 40 patients undergoing TKA was conducted to calculate the mean blood loss and occult blood loss according to Gross formula.

Results: The mean total blood loss was 1538 ml in these cases with occult blood loss of 791 ml.

[Rotational malalignment causing patellofemoral complications after total knee replacement].

Objective: To study the rotation of femoral component and tibial component with CT and evaluate the relationship between patellofemoral complications and rotational alignment of the components.

Methods: Thirty patients with isolated patellofemoral complications after total knee arthroplasty were compared with 20 patients with well functioning total knee replacements free of patellofemoral complications. The epicondylar axis and tibial tubercle were used as references on CT scans to quantify the rotational alignment of the femoral and tibial components.

[Ultrastructural changes of the skeletal muscle cells of rats subjected to exhausting exercises and the protective effect of vitamin E].

Objective: To investigate the ultrastructural changes of the mitochondria in the skeletal muscle cells of rats subjected to repeated exhausting exercises on treadmill and the protective effect of oral vitamin E.

Methods: Thirty male SD rats were randomized into control group (n=10), exhausting exercise group (n=10) and exhausting exercise group with oral vitamin E treatment (n=10), with the latter two groups taking repeated exhausting running exercises on the treadmill in a course of 4 weeks. At the end of the course of exercises, the rats were sacrificed and the quadriceps femoris muscles isolated for observation the ultrastructures of the skeletal muscle cells by transmission electron microscope (TEM).

[Effect of antioxidant vitamins on the exercise performance of rats].

Objective: To investigate the effect of antioxidant vitamins (vitamin E and vitamin C) on the exercise performance of rats.

Methods: Fifty male SD rats were randomly divided into control group (C), exhausting exercise control group (E), vitamin E group (M1), vitamin C group (M2) and vitamin E plus vitamin C group (M3). The rats in the exercising groups (E, M1, M2, M3) were propelled for repeated exhausting runs on the treadmill for 4 weeks.