Publications by authors named "Ji San Sun"

Article Synopsis
  • This study compared liver transplantation (LT) and liver resection (LR) in patients with hepatocellular carcinoma (HCC) who had portal vein tumor thrombus (PVTT) to determine which treatment was more effective and to find factors that influence prognosis.
  • A total of 94 patients were analyzed, split evenly between the two treatment options, and their outcomes in terms of recurrence-free survival (RFS) and overall survival (OS) were assessed, particularly focusing on PVTT types I and II.
  • Results indicated that LT generally offered a better prognosis than LR for patients with PVTT type I, especially those with high alpha-fetoprotein (AFP) levels, while no significant differences were found for patients with PVTT type
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Hepatocellular carcinoma (HCC) is the most common primary neoplasm of the liver and is one of the leading causes of cancer-related death worldwide. Liver transplantation (LT) has become one of the best curative therapeutic options for patients with HCC, although tumor recurrence after LT is a major and unaddressed cause of mortality. Furthermore, the factors that are associated with recurrence are not fully understood, and most previous studies have focused on the biological properties of HCC, such as the number and size of the HCC nodules, the degree of differentiation, the presence of hepatic vascular invasion, elevated serum levels of alpha-fetoprotein, and the tumor stage outside of the Milan criteria.

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Use of livers infected with Clonorchis sinensis as donor organs for transplantation is controversial because of the potential associated risks. The low availability of donor livers at Tianjin First Center Hospital since 2003 prompted us to undertake cadaveric liver transplantation in 14 patients using donor livers infected with C. sinensis.

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Background: Ischemic-type biliary lesions (ITBLs) play an extremely important role in influencing the long-term survival and quality of life of recipients after orthotopic liver transplantation (OLT). Some patients can be cured by interventional therapies, however others lose their grafts at last and receive liver retransplantation (re-OLT). The aim of this study was to analyze the data of 66 patients who had received re-OLT at our center because of ITBL and to discuss the treatment of ITBL after OLT.

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Objective: To investigate the long-term complications after liver transplantation.

Methods: Totally 85 living patients who received liver transplantation from December 30th 1998 to May 28th 2002 in Tianjin First Central Hospital were followed up till October 2007. Liver and kidney functions, blood drug levels, blood pressure, blood sugar, and blood fat were recorded and ultrasound imaging was performed during follow-up.

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