Cyclops lesions associated with both bundles and selective bundle repair of the anterior cruciate ligament.

Background: The remnant of a ruptured anterior cruciate ligament (ACL) can increase the risk of impingement or a cyclops lesion, which can increase challenges to proper tunnel placement.

Purpose: To evaluate the prevalence of cyclops lesions after ACL reconstruction and to assess the difference in the incidence of cyclops lesions between single-bundle repair and selective bundle repair of the ACL.

Material And Methods: This retrospective study included 151 patients who were diagnosed with an ACL tear after knee joint magnetic resonance imaging (MRI) who underwent ACL reconstruction surgery.

BAC cloning and heterologous expression of a giant biosynthetic gene cluster encoding antifungal neotetrafibricin in .

Polyene natural products including nystatin A1, amphotericin B, ECO-02301, and mediomycin belong to a large family of valuable antifungal polyketide compounds typically produced by soil actinomycetes. A previous study (Park et al., Front.

BAC Cloning of a Large-Sized Biosynthetic Gene Cluster of NPP B1, a Potential SARS-CoV-2 RdRp Inhibitor.

As valuable antibiotics, microbial natural products have been in use for decades in various fields. Among them are polyene compounds including nystatin, amphotericin, and nystatin-like polyenes (NPPs). Polyene macrolides are known to possess various biological effects, such as antifungal and antiviral activities.

Micro environment data on the Daeungbojeon hall and the Palsangjeon hall of the Beopjusa temple in Republic of Korea.

This article provides long-term environmental change data for wooden buildings; it also reflects environmental data provided by the Korea Meteorological Administration. In the case of field survey, data logger was installed on the left rear and right front sides of the buildings. Datasets on the Beopjusa temple were collected at 1 h intervals in each building.

Protein, Amino Acid, Oil, Fatty Acid, Sugar, Anthocyanin, Isoflavone, Lutein, and Antioxidant Variations in Colored Seed-Coated Soybeans.

Different physiological and genetic studies show that the variations in the accumulation of pigment-stimulating metabolites result in color differences in soybean seed coats. The objective of this study was to analyze the nutrient contents and antioxidant potential in black, brown, and green seed-coated soybeans. Significant variations in protein (38.

Pathological Mechanism of a Constitutively Active Form of Stromal Interaction Molecule 1 in Skeletal Muscle.

Stromal interaction molecule 1 (STIM1) is the main protein that, along with Orai1, mediates store-operated Ca entry (SOCE) in skeletal muscle. Abnormal SOCE due to mutations in STIM1 is one of the causes of human skeletal muscle diseases. STIM1-R304Q (a constitutively active form of STIM1) has been found in human patients with skeletal muscle phenotypes such as muscle weakness, myalgia, muscle stiffness, and contracture.

Calsequestrin: a well-known but curious protein in skeletal muscle.

Calsequestrin (CASQ) was discovered in rabbit skeletal muscle tissues in 1971 and has been considered simply a passive Ca-buffering protein in the sarcoplasmic reticulum (SR) that provides Ca ions for various Ca signals. For the past three decades, physiologists, biochemists, and structural biologists have examined the roles of the skeletal muscle type of CASQ (CASQ1) in skeletal muscle and revealed that CASQ1 has various important functions as (1) a major Ca-buffering protein to maintain the SR with a suitable amount of Ca at each moment, (2) a dynamic Ca sensor in the SR that regulates Ca release from the SR to the cytosol, (3) a structural regulator for the proper formation of terminal cisternae, (4) a reverse-directional regulator of extracellular Ca entries, and (5) a cause of human skeletal muscle diseases. This review is focused on understanding these functions of CASQ1 in the physiological or pathophysiological status of skeletal muscle.

QTL Mapping and Candidate Gene Analysis for Pod Shattering Tolerance in Soybean ().

Pod shattering is an important reproductive process in many wild species. However, pod shattering at the maturing stage can result in severe yield loss. The objectives of this study were to discover quantitative trait loci (QTLs) for pod shattering using two recombinant inbred line (RIL) populations derived from an elite cultivar having pod shattering tolerance, namely "Daewonkong", and to predict novel candidate QTL/genes involved in pod shattering based on their allele patterns.

Study on physical fitness factors affecting race-class of Korea racing cyclists.

The purpose of this study is to compare and analyze the difference of isokinetic muscle functions, anaerobic capabilities, pedaling power and maximum strength according to race-class of Korea racing cyclists. The participants in this study were 57 racing cyclist candidates who graduated from the Korea racing school. One year after graduation, we confirmed race-class of candidates and they were divided into three groups: the first-class racer group (FC, n=14), second-class racer group (SC, n=29), third-class racer group (TC, n=14).

Comparison of maximum muscle strength and isokinetic knee and core muscle functions according to pedaling power difference of racing cyclist candidates.

The purpose of this study was to investigate differences of maximum muscle strength and isokinetic knee and core muscle functions according to pedaling power of racing cyclist candidate. Subjects for this study were 200 racing cyclist candidates and divided into four groups: top 10% peak power group (TPP, n=20), low 10% peak power group (LPP, n=20), top 10% average power group (TAP, n=20), and low 10% average power group (LAP, n=20). The maximum muscle strength was consisted of grip strength, bench press and squat measured by Ariel device, and isokinetic knee and core muscle functions were analyzed by Humac Norm device.

Abrogation of B-Raf induced senescence by FoxM1 expression.

B-Raf oncogene mutation occurs in various cancers and is associated with tumor initiation. However, genetic modification of B-Raf in cells induces MAPK activation and results in oncogene-induced senescence. Overcoming the oncogene-induced senescence by B-Raf requires activation of another oncogene pathway, such as AKT signaling.

Prevalence, toxin gene profile, antibiotic resistance, and molecular characterization of from diarrheic and non-diarrheic dogs in Korea.

causes diarrhea and other diseases in animals and humans. We investigated the prevalence, toxin gene profiles, and antibiotic resistance of isolated from diarrheic dogs (DD) and non-diarrheic dogs (ND) in two animal hospitals in Seoul, Korea. Fecal samples were collected from clinically DD (n = 49) and ND (n = 34).

Evaluation of marginal fit of 2 CAD-CAM anatomic contour zirconia crown systems and lithium disilicate glass-ceramic crown.

Purpose: This study was to evaluate the marginal fit of two CAD-CAM anatomic contour zirconia crown systems compared to lithium disilicate glass-ceramic crowns.

Materials And Methods: Shoulder and deep chamfer margin were formed on each acrylic resin tooth model of a maxillary first premolar. Two CAD-CAM systems (Prettau®Zirconia and ZENOSTAR®ZR translucent) and lithium disilicate glass ceramic (IPS e.

Antagonist wear of three CAD/CAM anatomic contour zirconia ceramics.

Statement Of Problem: Little clinical information exists on the antagonist wear of anatomic contour zirconia crowns.

Purpose: The purpose of this in vitro study was to evaluate the 2-body wear of antagonists for 3 computer-aided design and computer-aided manufacturing (CAD/CAM) anatomic contour zirconia ceramics and veneering porcelain when opposing natural human enamel.

Material And Methods: Zirkonzahn Y-TZP (polished zirconia, zirconia with staining, zirconia with staining and glazing), Acucera Y-TZP, Wieland Y-TZP, and Noritake feldspathic ceramic were tested (6 groups).

Effect of far-infrared irradiation on catechins and nitrite scavenging activity of green tea.

The processed green tea leaves were irradiated by far-infrared (FIR) at eight temperatures (80, 90, 100, 110, 120, 130, 140, and 150 degrees C) for 10 min. After FIR irradiation, green teas were prepared by soaking the leaves in boiling water, and the physicochemical characteristics of the green tea were determined. FIR irradiation at 90 degrees C increased total phenol contents of green tea from 244.

Encapsulated Bifidobacterium bifidum potentiates intestinal IgA production.

We asked whether Bifidobacterium bifidum regulates the synthesis of IgA by mucosal lymphoid cells. B. bifidum alone, but not Clostridium perfringens, significantly induced total IgA and IgM synthesis by both mesenteric lymph nodes (MLN) and Peyer's patch (PP) cells.

Regulation of TNF-alpha-mediated hyperplasia through TNF receptors, TRAFs, and NF-kappaB in synoviocytes obtained from patients with rheumatoid arthritis.

Although the etiology of rheumatoid arthritis (RA) has not been clearly understood to date, the hyperplasia of the synovial membrane imposed by pro-inflammatory cytokines has been suggested to play a crucial role in the progression of this disease. TNF-alpha, a potent pro-inflammatory cytokine, was detected at highly enhanced concentrations in the blood and synovial fluids of patients with RA relative to those of patients with osteoarthritis and normal subjects. To evaluate the role of TNF-alpha in the synovial hyperplasia during the pathogenic state, we investigated cellular outcomes and molecular mechanisms of synoviocytes in response to TNF-alpha.