A new aglycone derivative from the saprophytic fungus .

A new aglycone derivative () and five known compounds () have been isolated from a saprophytic fungus for the first time. Their structures and absolute configurations were determined by nuclear magnetic resonance, high resolution mass spectrometry data and electronic circular dichroism. The bioactivities of all compounds were evaluated by cell analysis.

Interesting mycoparasites and gen. et sp. nov. (Hypocreales, Polycephalomycetaceae) from Yunnan Province, China.

A novel genus, was introduced to accommodate , based on a multigene phylogenetic analysis and its distinct morphological characteristics. Maximum likelihood (ML) and Bayesian inference analyses (BI) of ITS, SSU, LSU, , , and sequence data shown that formed an independent lineage nested between and . Morphologically, is distinguished from by the presence of a white subiculum on the stromata of Ophiocordycepscf.

Additions to the genus (Dothideomycetes); Three novel species and a new host record, based on morphology and phylogeny.

During a survey of microfungi associated with forest plants, four specimens related to were collected from decaying wood in Guizhou, Hainan and Yunnan Provinces, China. species have sexual and asexual forms. They are commonly found as saprophytes on decaying wood and have been reported as disease-causing pathogens in humans as well.

Novel drimane-type sesquiterpenoids and nucleosides from the Helicoma septoconstrictum suppress the growth of ovarian cancer cells.

Four new drimane-type sesquiterpenoids and two new nucleoside derivatives (1-6), were isolated from the fungus Helicoma septoconstrictum. Their structures were determined based on the combination of the analysis of their HR-ESI-MS, NMR, ECD calculations data and acid hydrolysis. All the isolated compounds were detected for their bio-activities against MDA-MB-231, A549/DDP, A2780 and HepG2 cell lines.

Morphophylogenetic evidence reveals four new fungal species within Tetraplosphaeriaceae (Pleosporales, Ascomycota) from tropical and subtropical forest in China.

Tetraplosphaeriaceae (Pleosporales, Ascomycota) is a family with many saprobes recorded from various hosts, especially bamboo and grasses. During a taxonomic investigation of microfungi in tropical and subtropical forest regions of Guizhou, Hainan and Yunnan provinces, China, several plant samples were collected and examined for fungi. Four newly discovered species are described based on morphology and evolutionary relationships with their allies inferred from phylogenetic analyses derived from a combined dataset of LSU, ITS, SSU, and DNA sequence data.

AaLaeA targets AaFla1 to mediate the production of antitumor compound in Alternaria alstroemeria.

Endophytic fungi are an important source of novel antitumor substances. Previously, we isolated an endophytic fungus, Alternaria alstroemeria, from the medicinal plant Artemisia artemisia, whose crude extracts strongly inhibited A549 tumor cells. We obtained a transformant, namely AaLaeA , which completely loses its antitumor activity due to overexpression of the global regulator AaLaeA.

Two new fungal genera () found on in Thailand.

is a species-rich order of fungi that includes endophytes, saprobes, and pathogens associated with forest plants and crops. They may also occur as parasites or secondary invaders of plant tissues injured or infected by other organisms or inhabit living animal and human tissues, as well as soil. Meanwhile, some severe pathogens wipe out large-scale cultivations of profitable crops, timber monocultures, and forests.

New Spirostane from a Fungus Neohelicomyces hyalosporus and Its Bioactivity.

A new spirostane, namely neohelicomyine B (1), together with six known steroids (2-7) were isolated from the fermentation of fungus Neohelicomyces hyalosporus. The structures of these compounds were elucidated by extensive analyses of spectroscopic methods including 1D and 2D NMR and HR-ESI-MS. The absolute configuration of 1 was confirmed by single-crystal X-ray diffraction.

New Guaiane-Type Sesquiterpenoids Biscogniauxiaols A-G with Anti-Fungal and Anti-Inflammatory Activities from the Endophytic Fungus .

Seven undescribed guaiane-type sesquiterpenoids named biscogniauxiaols A-G (-) were isolated from the endophytic fungus on Their structures were determined by extensive spectroscopic analyses, electronic circular dichroism (EC) and specific rotation (SR) calculations. Compound represented a new family of guaiane-type sesquiterpenoids featuring an unprecedented [5/6/6/7] tetracyclic system. A plausible biosynthetic pathway for compounds - was proposed.

Diversity, morphology, and molecular phylogeny of from southern China.

During an investigation of from southern China, 10 xylariales-like taxa have been collected. Morphological and multi-gene analyses confirmed that these taxa reside in and represent eight novel taxa and two new records belonging to six genera ., , and gen.

Neogrisphenol A, a Potential Ovarian Cancer Inhibitor from a New Record Fungus .

From the rice fermentation product of a new record fungus, , two new polyketides, neogrisphenol A () and neogrisphenol B (), one new isochroman-1-one, ()-6-hydroxy-7-methoxy-3,5-dimethylisochroman-1-one (), and four known compounds (-) were isolated. Their structures were determined using 1D- and 2D-NMR, mass spectrometry, and chemical calculations. The C-3~C-2' polymerization mode between the two -naphthalenone derivative moieties is uncommon in compounds and .

New species and records of , and (Pezizomycotina, Ascomycota) associated with palm and bamboo from China.

Several micro fungi were gathered from bamboo and palm in Guizhou Province, China. In morphology, these taxa resemble , and . Multi-gene phylogenetic analyses based on combined ITS, LSU, SSU, 2 and 1 loci confirmed that two are new geographical records for China, (, ), while two of them are new to science ( sp.

A new alkaloid derivative from the saprophytic fungus PF11-1.

A new alkaloid, neohelicomyine A (), along with two known alkaloids (-), were isolated from the fermentation of PF11-1. The structures of these compounds were elucidated by extensive analyses of spectroscopic methods including 1 D and 2 D NMR, HRESIMS and ECD. The bioactivities of all compounds were evaluated using cellular assays, and compounds and displayed moderate cytotoxicities against human cancer (A549, TCA, RD) cells with IC values of 26-87 μg/mL.

Four new species and three new records of helicosporous hyphomycetes from China and their multi-gene phylogenies.

Helicosporous hyphomycetes have the potential to produce a variety of bioactive compounds. However, the strain resources of this fungal group are relatively scarce, which limits their further exploitation and utilization. In this study, based on phylogenetic analyses of combined ITS, LSU, RPB2, and TEF1α sequence data and the morphology from 11 isolates, we introduce four new species of helicosporous hyphomycetes, , and , as well as three new records, , and .

Multi-Gene Phylogenetic Analyses Revealed Five New Species and Two New Records of from China.

Eight hyphomycetes were collected as part of an investigation into the diversity of hyphomycetous fungi in China. Based on morphology and multi-loci (LSU, ITS, tef1α, and rpb2) phylogenetic analyses, five new taxa, including a new Aquapteridospora species A. hyalina and four novel Distoseptispora species, viz D.

Morphological and Phylogenetic Analyses Reveal Five New Species in Chaetosphaeriaceae.

Chaetosphaeriaceae is a genera-rich and highly diverse group of fungi with a worldwide distribution in terrestrial and aquatic habitats. Eight fresh collections of Chaetosphaeriaceae were obtained during investigations of hyaline-spored hyphomycetes in China and Thailand. Based on morphological characteristics and phylogenetic analysis of a combined LSU and ITS sequence dataset, , , , and were introduced as new species, was reported as new host record, and and were introduced as new collections.

Morpho-molecular characterisation of , with and sp. nov. and comb. nov.

Three arecophila-like fungal samples were collected on dead culms of gramineous plants in China. Morphological studies of our new collections and the herbarium specimen of (generic type) were conducted and the morphological affinity of our new collections with was confirmed. Maximum likelihood and Bayesian analyses using combined ITS, LSU, 2 and β-tubulin data from our collections revealed the phylogeny of .

Three new species of (Xylariomycetidae): , and .

Three fungal specimens (two sexual and one asexual) were collected during fieldwork conducted in China, Taiwan and Thailand. Both sexual morphs share superficial, black ascomata surrounded by flexuous setae; 8-spored, unitunicate, cylindrical asci, with J+, apical ring, and ellipsoidal to allantoid, aseptate, guttulate ascospores. The asexual morph has ceratosporium-like conidia arising from aerial hyphae with a single arm and are usually attached or with 2-3 arms, brown, often with a subglobose to conical cell at the point of attachment.

A taxonomic study of from China, with six new species.

During an investigation of Xylariaceae from 2019 to 2020, isolates representing eight (Xylariacese) species were collected from Yunnan, Guizhou and Hainan Provinces in China. Morphological and multi-gene phylogenetic analyses, based on combined ITS, α-actin, and β-tubulin sequences, confirmed that six of them are new to science, viz. , , , , and ; one is a new record () for China and one is a known species ().

Morpho-molecular characterization of sp. nov. and a new host record for .

Collections of fungal samples from two dead leaf specimens from Italy were subjected to morphological examination and phylogenetic analyses. Two coelomycetous taxa belonging to two different genera in Xylariomycetidae, Sordariomycetes, namely and , were identified. The taxon is revealed as a new species and is herein introduced as while the taxon is identified as .

gen. et sp. nov. and sp. nov. (Diatrypaceae) from China.

Background: In this study, we introduce a novel genus, , of the family Diatrypaceae comprising three species viz. sp. nov.

A Bilobalide-Producing Endophytic Fungus, Pestalotiopsis uvicola from Medicinal Plant Ginkgo biloba.

For screening bilobalide (BB)-producing endophytic fungi from medicinal plant Ginkgo biloba, a total of 57 fungal isolates were isolated from the internal stem, root, leaf, and bark of the plant G. biloba. Fermentation processes using BB-producing fungi other than G.

Records of Hedotettix and Teredorus in Thailand with the description of three new species (Orthoptera, Tetrigidae).

We are studying the fungi associated with insects in northern Thailand and as a result several rarely collected insect species have been uncovered. The genera Hedotettix with one new species and Teredorus with two new species are reported from Thailand. Hedotettix triangularis Zha & Hyde, sp.