Publications by authors named "Jhony A De La Cruz Vargas"

Background: To determine the sociodemographic factors associated with knowledge and adequate attitudes about HIV in women of reproductive age from Peru in 2021.

Materials And Methods: Analytical cross-sectional study. We analyzed a demographic and family health survey (ENDES) 2021 carried out in women of reproductive age (12 to 49 years of age).

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Introduction: Breast cancer is a disease with high global prevalence. Clinical inflammatory biomarkers have been proposed as prognostic indicators in oncology. This research aims to determine the relationship between inflammatory markers and overall survival in breast cancer patients from four representative hospitals in Lima, Peru.

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Objective: To determine the quality of systematic reviews submitted as a thesis in the Medical School of Ricardo Palma University.

Methods: We conducted a systematic review. We included systematic reviews submitted as theses from Ricardo Palma University, and we excluded narrative reviews, editorials, clinical experiments, and those with incomplete data.

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The pan-immune-inflammation value (PIV), calculated as (neutrophil × platelet × monocyte)/lymphocyte count, may be useful for estimating survival in breast cancer patients. To determine the prognostic value of PIV for overall survival in breast cancer patients in Lima, Peru. A retrospective cohort study was conducted.

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Objective: To determine the factors associated with undiagnosed hypertension.

Method: A quantitative, observational, retrospective, cross-sectional and analytical study was carried out in people aged 15 years and over included in the Demographic and Family Health Survey from 2019 to 2021 in Peru. A statistical analysis was carried out using the corrected F test, and crude and adjusted prevalence ratio (aPR), with a 95% confidence interval (95%CI) for inferential analysis, through Poisson regression with robust variance.

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Background: Limited evidence exists on the population attributable fraction (PAF) of cancer cases and deaths in Latin America. In Peru several studies have been published regarding the PAF of various risk factors and their associated diseases. The objective of this study was to estimate the fraction of cancer cases and deaths attributable to potentially modifiable risk factors in Peru in 2018, before the COVID-19 pandemic in the population of 15 years old and older.

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Introduction: Family planning is a right and a tool that offers the possibility of choosing how many children to have. Its importance lies in the possibility of avoiding an unwanted pregnancy and its consequences. Our objective was to determine the factors associated with discontinuing hormonal contraceptives in women of childbearing age who attended the La Libertad Health Center in January 2023.

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Objective: This study aimed to determine how metabolic syndrome is related to benign prostatic enlargement in males under 60 years old in a national military hospital in Peru.

Materials And Methods: We conducted a retrospective, quantitative, case-control study. By simple random sampling, 87 cases with benign prostatic enlargement and 174 controls were included, with a statistical power of 80%.

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Peru was severely affected by COVID-19 with a fatality rate that reached up to 6%. In this study, the relationship between SARS-CoV-2 variants and COVID-19 disease outcome in Amazonas, a region of northeastern Peru, was evaluated. The variants were determined by genomic sequencing, and clinical-epidemiological data were collected from 590 patients between April 2021 and February 2022.

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Background: Endemic pemphigus foliaceus and endemic pemphigus vulgaris are autoimmune dermatologic disorders endemic to the Peruvian Amazon.

Objective: To determine the ultrastructural skin alterations of three healthy subjects with anti DSG-1 antibodies in areas endemic to pemphigus foliaceus and pemphigus vulgaris in the Peruvian Amazon.

Patients And Methods: Case series carried out from data of three clinically healthy subjects positive to anti DSG-1 antibodies, from Peru.

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Purpose: It has been reported that intravitreal Ziv-aflibercept is a safe and effective drug for the treatment of diabetes macular edema (DME). The objective of this study was to evaluate in a real-life setting, the efficacy of intravitreal Ziv-aflibercept in the treatment of DME after the administration of three consecutive monthly doses.

Methods: A single arm, prospective cohort study.

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Due to the increase in obesity worldwide, international organizations have promoted the adoption of a healthy lifestyle, as part of which fruit consumption stands out. However, there are controversies regarding the role of fruit consumption in mitigating this disease. The objective of the present study was to analyze the association between fruit intake and body mass index (BMI) and waist circumference (WC) in a representative sample of Peruvians.

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Background: Research in universities requires systematic and participatory processes that integrate teachers, contents, strategies and tools, and students and their own interests. Therefore, the main objective of this study was to establish the relationship between the perception of the teaching-learning process (TLP) and the attitude toward scientific research among midwifery students.

Materials And Methods: Descriptive cross-sectional study, conducted on 250 students from second to fourth year of study selected by convenience sampling.

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Introduction: Obesity and depression contribute to the global burden of economic cost, morbidity, and mortality. Nevertheless, not all people with obesity develop depression.

Objective: To determine the factors associated with depressive symptoms among people aged 15 or older with obesity from the National Demographic and Family Health Survey (ENDES in Spanish 2019-2021).

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Background And Aim: Peru is the country with the highest mortality rate from COVID-19 globally, so the analysis of the characteristics of deaths is of national and international interest. The aim was to determine the epidemiological characteristics of deaths from COVID-19 in Peru from 28 March to 21 May 2020.

Methods: Deaths from various sources were investigated, including the COVID-19 Epidemiological Surveillance and the National System of Deaths (SINADEF).

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Background: Peru has some of the worst outcomes worldwide as a result of the SARS-CoV-2 pandemic; it is presumed that this has also affected healthcare workers. This study aimed to establish whether occupation and other non-occupational variables were risk factors for possible reinfection, hospitalization, and mortality from COVID-19 in cohorts of Peruvian healthcare workers infected with SARS-CoV-2.

Methods: Retrospective cohort study.

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Diffuse large B-cell lymphoma (DBLCL) is the most common type of non-Hodgkin's lymphoma (NHL). Triple expressor lymphoma is a subgroup of non-Hodgkin's lymphomas that exhibits simultaneous overexpression of the MYC, BCL2, and BCL6 genes. This entity is characterized by its aggressive behavior and its poor response to chemotherapy regimens traditionally used, such as the standard R-CHOP (rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone) regimen.

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Article Synopsis
  • The study aimed to analyze the effects of chronic arsenic exposure from mine tailings on skin lesions in individuals from two highland mining regions in Peru.
  • A total of 17 people were evaluated, revealing an average exposure duration of 16.5 years and common skin manifestations like plantar and palmar keratosis.
  • Findings indicated that most lesions were mild to moderate, with no cases of skin cancer and a lower urine arsenic clearance compared to other arsenicism forms.
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Article Synopsis
  • * Researchers conducted a cross-sectional study with 594 children under 18, finding a 64.8% prevalence of photodermatoses, notably actinic prurigo and pityriasis alba.
  • * Results indicated that living near a mini hole in the ozone layer and at altitudes above 3500 meters significantly increased the risk of developing skin conditions.
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Background: Stress and unhealthy lifestyle are serious problems in public health and education, particularly due to their significant relevance in the context of the COVID-19 pandemic.

Objectives: To determine the correlation between stress and lifestyle in teachers at some schools in Lima, Peru, during telework in 2020.

Methods: This observational, quantitative, analytical, cross-sectional study was conducted in 217 school teachers from Lima.

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Introduction: COVID-19 has caused great fear on health professionals and could affect their mental health, therefore it is important to determine the association between the perception of risk to COVID-19 and mental health in workers of a Peruvian hospital.

Methods: Analytical cross-sectional study, through virtual survey. The dependent variables were: depression, anxiety and stress; The independent variable was perception of risk to COVID-19 and the covariates: sociodemographic, family, work and clinical data.

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Objective: To determine the factors associated with excessive daytime sleepiness (EDS) in informal interprovincial transport drivers of the Lima-Huancayo central highway (Peru) from January to March 2018.

Methods: Cross-sectional study. The drivers were weighed and measured, then individual, sociodemographic, and occupational data were obtained which were recorded in a data collection form, then the Epworth Sleepiness Scale (ESS) was applied to the drivers.

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Objective: To determine how clinical and laboratory factors were associated with nosocomial pneumonia in adult patients hospitalized in an internal medicine department.

Methods: We conducted a retrospective unmatched case-control study. We recorded clinical and epidemiological data from patients discharged from an internal medicine department of a Peruvian reference hospital, the Hospital Nacional Arzobispo Loayza, between 2016 and 2018.

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Purpose: The purpose of this study is to evaluate the frequency of viral and bacterial respiratory pathogens detected by molecular methods in sputum samples of patients hospitalized for COVID-19 and to evaluate its impact on mortality and unfavorable outcomes (in-hospital death or mechanical ventilation).

Patients And Methods: The prospective cohort included patients with diagnosis of COVID-19 hospitalized at Hospital Nacional Hipólito Unanue. Sociodemographic and clinical data were collected from clinical records.

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